PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26139123-1 2015 AIMS: To develop salinomycin-loaded poly(lactic-co-glycolic acid) nanoparticles conjugated with both CD133 aptamers A15 and EGFR aptamers CL4 (CESN), to target hepatocellular carcinoma (HCC) cells simultaneously expressing EGFR and CD133. salinomycin 17-28 carboxylesterase 1C Mus musculus 143-147 26139123-3 2015 RESULTS & CONCLUSION: The cytotoxicity of CESN in HCC cells and CD133(+) HCC cells was superior to that of A15 or CL4-conjugted or nontargeted salinomycin-loaded nanoparticles. salinomycin 147-158 carboxylesterase 1C Mus musculus 46-50 26139123-5 2015 We speculated that the improved therapeutic effect of CESN may be attributed to both targeting a higher percentage of HCC cells and increased delivery of salinomycin to HCC cells. salinomycin 154-165 carboxylesterase 1C Mus musculus 54-58