PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17230533-7 2007 The frequencies of apoptotic cells induced by the catechol estrogens were modified by the COMT inhibition in a manner similar to those observed with the chromosome aberrations assay and the cell transformation assay, indicating that each effect by the catechol estrogens at the three measured endpoints might be caused by a mechanism similar to the others. catechol 50-58 catechol O-methyltransferase Mesocricetus auratus 90-94 17230533-8 2007 Our findings indicate that COMT activity has an influence on cell transforming activity and its related genetic effects of catechol estrogens in SHE cells, which implies that an individual activity of COMT may be one of the etiological factors in endogenous estrogen-induced carcinogenesis. catechol 123-131 catechol O-methyltransferase Mesocricetus auratus 27-31 17230533-8 2007 Our findings indicate that COMT activity has an influence on cell transforming activity and its related genetic effects of catechol estrogens in SHE cells, which implies that an individual activity of COMT may be one of the etiological factors in endogenous estrogen-induced carcinogenesis. catechol 123-131 catechol O-methyltransferase Mesocricetus auratus 201-205