PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8031317-3 1994 In this paper we followed the ability of benzene and its metabolites, phenol, catechol, hydroquinone and benzoquinone to destroy CYP in liver microsomes from PB rats in vitro. catechol 78-86 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 129-132 10462055-4 1999 This study followed the ability of quinonic benzene metabolites (catechol, hydroquinone, and benzoquinone) to destroy CYP in liver microsomes from rats pretreated with various inducers and in human liver microsomes. catechol 65-73 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 118-121 8031317-5 1994 (2) Quinonic metabolites of benzene cause CYP destruction with different potency (30% CYP was destroyed by 3 mM catechol, 0.3 mM hydroquinone and 0.03 mM benzoquinone). catechol 112-120 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 42-45 8031317-5 1994 (2) Quinonic metabolites of benzene cause CYP destruction with different potency (30% CYP was destroyed by 3 mM catechol, 0.3 mM hydroquinone and 0.03 mM benzoquinone). catechol 112-120 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 86-89 1974641-10 1990 These results indicate that MDMA is oxidized by cytochrome P-450 to the catechol and the catecholamine oxidized by superoxide to a quinone to which GSH or other thiol functions add. catechol 72-80 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 48-64 25989628-3 1990 The major pathway of metabolism I involved cytochrome P-450-mediated cleavage of the methylenedioxy ring to yield catechol derivatives. catechol 114-122 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 43-59 2848987-7 1988 The differential effect of these metal ions on estrogen metabolism gives additional support for two different mechanisms in the cytochrome P-450-catalyzed formation of catechol estrogens and their further activation to form protein conjugates. catechol 168-176 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 128-144 6311216-0 1983 Regulation of cytochrome P-450-dependent catechol estrogen formation in rat liver microsomes. catechol 41-49 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 14-30 410418-0 1977 Cytochrome P-450 and NADPH cytochrome c reductase in rat brain: formation of catechols and reactive catechol metabolites. catechol 77-85 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 0-16