PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10433224-5 1999 Almost 90% of accumulated DHAA was present as ascorbic acid within 2 h. Preculture of cells for 24 h with FSH (50 ng/ml) and IGF-I (30 ng/ml) significantly stimulated DHAA uptake compared with the control (158 +/- 16 vs. 43 +/- 8 pmol/10(6) cells, respectively). Dehydroascorbic Acid 26-30 insulin-like growth factor 1 Rattus norvegicus 125-130 10433224-5 1999 Almost 90% of accumulated DHAA was present as ascorbic acid within 2 h. Preculture of cells for 24 h with FSH (50 ng/ml) and IGF-I (30 ng/ml) significantly stimulated DHAA uptake compared with the control (158 +/- 16 vs. 43 +/- 8 pmol/10(6) cells, respectively). Dehydroascorbic Acid 167-171 insulin-like growth factor 1 Rattus norvegicus 125-130 10433224-7 1999 Northern and Western analysis of GLUT1 in granulosa cells following 24 h coincubation with FSH and IGF-I revealed up-regulation of GLUT1 at both the messenger RNA and protein levels (1.6- and 1.3-fold of control, respectively), suggesting that the stimulatory effects of FSH and IGF-I on DHAA transport are mediated by the induction of GLUT1. Dehydroascorbic Acid 288-292 insulin-like growth factor 1 Rattus norvegicus 99-104 9475396-13 1998 However, 24-h preincubation with insulin-like growth factor (IGF)-I dose-dependently (10-100 ng/ml) stimulated DHAA uptake; similar concentrations of IGF-II had no effect. Dehydroascorbic Acid 111-115 insulin-like growth factor 1 Rattus norvegicus 33-67 9421397-8 1998 We conclude that insulin and IGF-I stimulate osteoblastic uptake of DHAA through facilitative hexose transporters. Dehydroascorbic Acid 68-72 insulin-like growth factor 1 Rattus norvegicus 29-34