PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32712713-4	2020	Several case reports have reported that flucloxacillin appeared to decrease levels of drugs metabolized by CYP3A4 and P-gp.	Floxacillin	40-54	ATP binding cassette subfamily B member 1	Homo sapiens	118-122	
32712713-11	2020	CONCLUSIONS: Flucloxacillin decreases tacrolimus trough levels, possibly through a CYP3A4 and/or P-gp-inducing effect.	Floxacillin	13-27	ATP binding cassette subfamily B member 1	Homo sapiens	97-101	
16472102-0	2006	Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin.	Floxacillin	92-106	ATP binding cassette subfamily B member 1	Homo sapiens	37-51	
16472102-4	2006	However, incubation of human LS 180 colorectal adenocarcinoma cells with flucloxacillin led to a dose-dependent induction of MDR1 as well as of CYP3A4 mRNA, which was also confirmed in primary human hepatocytes.	Floxacillin	73-87	ATP binding cassette subfamily B member 1	Homo sapiens	125-129	
16472102-9	2006	These findings indicate that flucloxacillin has the potential to induce expression of both CYP3A4 as well as P-glycoprotein, most likely through activation of the nuclear hormone receptor PXR.	Floxacillin	29-43	ATP binding cassette subfamily B member 1	Homo sapiens	109-123