PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29251736-10	2018	Amiloride (ENaC) and hydrochlorothiazide (pendrin inhibitor) equally attenuated the effect of PGE2 on sodium transport.	Hydrochlorothiazide	21-40	solute carrier family 26, member 4	Mus musculus	42-49	
16825334-6	2006	Moreover, in response to hydrochlorothiazide administration, pendrin was downregulated despite a marked secondary hyperaldosteronism.	Hydrochlorothiazide	25-44	solute carrier family 26, member 4	Mus musculus	61-68	
28750403-0	2017	Ablation of the Cl-/HCO3- Exchanger Pendrin Enhances Hydrochlorothiazide-Induced Diuresis.	Hydrochlorothiazide	53-72	solute carrier family 26, member 4	Mus musculus	36-43	
28750403-2	2017	We hypothesized that deletion of pendrin leaves NCC as the major salt absorbing transporter in the distal nephron and therefore enhances salt excretion by hydrochlorothiazide (HCTZ).	Hydrochlorothiazide	155-174	solute carrier family 26, member 4	Mus musculus	33-40	
28750403-2	2017	We hypothesized that deletion of pendrin leaves NCC as the major salt absorbing transporter in the distal nephron and therefore enhances salt excretion by hydrochlorothiazide (HCTZ).	Hydrochlorothiazide	176-180	solute carrier family 26, member 4	Mus musculus	33-40	
28750403-6	2017	Urine output and water intake increased significantly only in pendrin KO mice in response to HCTZ, but not in WT or NCC KO mice.	Hydrochlorothiazide	93-97	solute carrier family 26, member 4	Mus musculus	62-69	
28750403-7	2017	Sodium and chloride excretion increased in HCTZ-treated pendrin KO mice, but they remained unchanged in WT or NCC KO mice.	Hydrochlorothiazide	43-47	solute carrier family 26, member 4	Mus musculus	56-63	
28750403-8	2017	Pendrin KO mice treated with HCTZ developed volume depletion, as determined by increased expression of renin mRNA and protein.	Hydrochlorothiazide	29-33	solute carrier family 26, member 4	Mus musculus	0-7	
28750403-9	2017	The expression of ENaC and pendrin increased in HCTZ-treated WT mice.	Hydrochlorothiazide	48-52	solute carrier family 26, member 4	Mus musculus	27-34	
28750403-11	2017	CONCLUSION: The ablation of the Cl-/HCO3- exchanger Pendrin enhances the magnitude of salt wasting by HCTZ.	Hydrochlorothiazide	102-106	solute carrier family 26, member 4	Mus musculus	52-59