PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31327267-6 2019 A relatively small number of gene variants related to loci associated with drug-signaling pathways (KCNK3, SULT1C3, AMH, PDE3A, PLCE1, PRKAG2) with large effect size (-3.5 to +3.5 mm Hg difference in response per allele) and differing allele frequencies in black versus white individuals explained a large proportion of the difference in response to candesartan and hydrochlorothiazide between these groups. Hydrochlorothiazide 366-385 potassium two pore domain channel subfamily K member 3 Homo sapiens 100-105