PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22248668-5 2011 p53 negatively regulates glycolysis through activation of TIGAR (an inhibitor of the fructose-2,6-bisphosphate). fructose 2,6-diphosphate 85-110 tumor protein p53 Homo sapiens 0-3 28092678-4 2017 Depletion of PFKFB4 from p53-deficient cancer cells increased levels of the allosteric regulator fructose-2,6-bisphosphate, leading to increased glycolytic activity but decreased routing of metabolites through the oxidative arm of the pentose-phosphate pathway. fructose 2,6-diphosphate 97-122 tumor protein p53 Homo sapiens 25-28