PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12573485-2	2003	The core of the PBRU contains two nuclear receptor sites, NR-1 and NR-2, and a nuclear factor-1 (NF 1) binding site, which are required for PB responsiveness, but the importance of sequences flanking the core is not clear.	Phenobarbital	16-18	neurofibromin 1	Mus musculus	97-101	
10072770-5	1999	DNA affinity enrichment techniques and immunoblotting and electromobility shift assays were used to determine that nuclear factor 1 (NF-1) interacts strongly with a site centered at -2200bp in the PB responsive unit (PBRU) of CYP2B2.	Phenobarbital	197-199	neurofibromin 1	Mus musculus	133-137	
10072770-6	1999	To test the functional contribution of NF-1 in PB activation, we introduced specific mutations within the PBRU NF-1 element and demonstrated that these mutations completely ablate the binding interaction.	Phenobarbital	47-49	neurofibromin 1	Mus musculus	39-43	
10072770-7	1999	However, transgenic mice incorporating the mutant NF-1 sequence within an otherwise wild-type -2500/CYP2B2 transgene maintained full PB responsiveness.	Phenobarbital	133-135	neurofibromin 1	Mus musculus	50-54