PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25301449-6 2014 Mechanistically, SKLB316 could decrease the activities of cdc2/cyclin B1 complex, including decreasing the synthesis of cyclin B1, cdc2 and cdc25c, while accumulating the levels of phosphorylated cdc2 (Tyr15) and checkpoint kinase 2. sklb316 17-24 cell division cycle 25C Homo sapiens 140-146