PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34861585-9 2022 The circulating level of IL-6 but not TNF-alpha was significantly decreased by AL. alantolactone 79-81 interleukin 6 Mus musculus 25-29 34861585-12 2022 AL also ameliorated C2C12 myotube atrophy induced by IL-6 and inhibited IL-6-mediated STAT3 activation. alantolactone 0-2 interleukin 6 Mus musculus 53-57 34861585-12 2022 AL also ameliorated C2C12 myotube atrophy induced by IL-6 and inhibited IL-6-mediated STAT3 activation. alantolactone 0-2 interleukin 6 Mus musculus 72-76 33556301-7 2021 RESULTS: In CIA mice, alantolactone at 50 mg/kg attenuated RA symptoms, including high arthritis scores, infiltrating inflammatory cells, synovial hyperplasia, bone erosion and levels of the proinflammatory cytokines TNF-alpha, IL-6 and IL-17A, but not IL-10 in paw tissues. alantolactone 22-35 interleukin 6 Mus musculus 228-232 34202301-8 2021 Furthermore, alantolactone treatment in mice significantly alleviated the severity of skin lesions (erythema, scaling and epidermal thickness, and inflammatory cell infiltration) and decreased the mRNA expression of inflammatory cytokines (e.g., TNF-alpha, IL-6, IL-1beta, IL-8, IL-17A, and IL-23) in an IMQ-induced-like mouse model. alantolactone 13-26 interleukin 6 Mus musculus 257-261