PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8576635-4 1995 Incubation of cafestol with CaCo-2 cells induced a 3-fold up-regulation of LDL receptor mRNA, as compared to control cells. cafestol 14-22 low density lipoprotein receptor Homo sapiens 75-87 8576635-10 1995 We conclude that cafestol promotes an enhanced rate of uptake and degradation of LDL, probably due to an increase in transcription of LDL receptor mRNA and a reduced secretion of cholesteryl ester and triacylglycerol in CaCo-2 cells. cafestol 17-25 low density lipoprotein receptor Homo sapiens 134-146