PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2951469-7 1987 ApoB isolated by this procedure was essentially identical to apoB from autologous LDL with respect to molecular weight, secondary structure, amino acid composition, and sialic acid content. N-Acetylneuraminic Acid 169-180 apolipoprotein B Homo sapiens 0-4 17368571-1 2007 The function of gangliosides, sialic acid-containing glycolipids, on the secretion and assembly of apoB-containing lipoproteins is poorly understood. N-Acetylneuraminic Acid 30-41 apolipoprotein B Homo sapiens 99-103 3014270-8 1986 Other known apolipoprotein modifications include the modification of apoB, apoC-III, and apoD with carbohydrate chains that contain sialic acid and the proteolytic cleavage of the proapoA-II segment. N-Acetylneuraminic Acid 132-143 apolipoprotein B Homo sapiens 69-73 27468569-0 2016 Serum Sialic Acid Concentration and Content in ApoB-Containing Lipoproteins in Liver Diseases. N-Acetylneuraminic Acid 6-17 apolipoprotein B Homo sapiens 47-51 27468569-2 2016 In VILDL and LDL sialic acid is attached to apolipoprotein B. N-Acetylneuraminic Acid 17-28 apolipoprotein B Homo sapiens 44-60 27468569-4 2016 Therefore, the aim of this study was to assess the effect of liver diseases on the concentration and content of SA in ApoB-containing lipoproteins. N-Acetylneuraminic Acid 112-114 apolipoprotein B Homo sapiens 118-122 27468569-6 2016 ApoB-containing lipoproteins were isolated by a turbidimetric procedure and SA concentration was measured according to an enzymatic method. N-Acetylneuraminic Acid 76-78 apolipoprotein B Homo sapiens 0-4 27468569-7 2016 RESULTS: There was a significant increase in the serum concentration of SA in ApoB-containing lipoproteins in viral hepatitis. N-Acetylneuraminic Acid 72-74 apolipoprotein B Homo sapiens 78-82 27468569-8 2016 Although the serum concentration of ApoB was not significantly different between specific liver diseases, the serum levels of SA in ApoB-containing lipoproteins appeared to be different. N-Acetylneuraminic Acid 126-128 apolipoprotein B Homo sapiens 132-136 27468569-11 2016 The content of SA in ApoB-containing lipoproteins in alcoholic cirrhosis and viral hepatitis was significantly higher than that in the control group, but did not differ between diseases. N-Acetylneuraminic Acid 15-17 apolipoprotein B Homo sapiens 21-25 27468569-13 2016 It seems that the reason for these abnormalities is the changes in the concentration of sialic acid in ApoB-containing lipoproteins. N-Acetylneuraminic Acid 88-99 apolipoprotein B Homo sapiens 103-107 18633759-9 2008 Correlation analysis revealed a significant association between the protein bound sialic acid with hsCRP, LDL cholesterol, and LDL-C/Apo-B. N-Acetylneuraminic Acid 82-93 apolipoprotein B Homo sapiens 133-138 20663853-2 2010 METHODS: The level of SA in apolipoprotein B (apoB)-containing lipoproteins was determined by using enzymatic assay followed by the precipitation step in 126 alcohol-dependent men. N-Acetylneuraminic Acid 22-24 apolipoprotein B Homo sapiens 28-44 20663853-2 2010 METHODS: The level of SA in apolipoprotein B (apoB)-containing lipoproteins was determined by using enzymatic assay followed by the precipitation step in 126 alcohol-dependent men. N-Acetylneuraminic Acid 22-24 apolipoprotein B Homo sapiens 46-50 20663853-3 2010 RESULTS: Increased level and content of SA in apoB-containing lipoproteins was found not only in the hyperlipidemic alcoholic subjects but also in normolipidemic subjects. N-Acetylneuraminic Acid 40-42 apolipoprotein B Homo sapiens 46-50 20663853-5 2010 The increase of SA level in apoB-containing lipoproteins in type IIb hyperlipidemia is accompanied by an increase of serum apoB concentration. N-Acetylneuraminic Acid 16-18 apolipoprotein B Homo sapiens 28-32 20663853-5 2010 The increase of SA level in apoB-containing lipoproteins in type IIb hyperlipidemia is accompanied by an increase of serum apoB concentration. N-Acetylneuraminic Acid 16-18 apolipoprotein B Homo sapiens 123-127 20663853-6 2010 Increased level and content of SA in apoB-containing lipoproteins did not correlate with any markers of alcohol abuse and lipid status. N-Acetylneuraminic Acid 31-33 apolipoprotein B Homo sapiens 37-41 20663853-7 2010 CONCLUSIONS: There are changes in the structure of atherogenic lipoproteins in alcoholics, which consist of increasing SA concentration in apoB-containing lipoproteins. N-Acetylneuraminic Acid 119-121 apolipoprotein B Homo sapiens 139-143 11079462-8 2000 These results indicate that sialic acid residues of apo B- 100 play an important role in cellular uptake and degradation of LDL. N-Acetylneuraminic Acid 28-39 apolipoprotein B Homo sapiens 52-62 15989730-1 2005 BACKGROUND: A convenient method for the measurement of sialic acid in plasma apoB-containing lipoproteins is described. N-Acetylneuraminic Acid 55-66 apolipoprotein B Homo sapiens 77-81 15989730-4 2005 The contents of sialic acid in apoB were 2.03+/-0.41%, 2.09+/-0.35% (no significance versus normal), 1.86+/-0.27% (P<0.0001), 1.97+/-0.26% (P<0.02), and 2.28+/-0.41% (P<0.002), for normal, all types of hyperlipidaemia, types IIa, IIb, and IV, respectively. N-Acetylneuraminic Acid 16-27 apolipoprotein B Homo sapiens 31-35 15989730-5 2005 CONCLUSION: The content of sialic acid in apoB decreased significantly in type IIa but increased in type IV hyperlipidaemia, which may reflect the presence of sialic acid in very low-density lipoprotein apolipoproteins other than apoB. N-Acetylneuraminic Acid 27-38 apolipoprotein B Homo sapiens 42-46 15989730-5 2005 CONCLUSION: The content of sialic acid in apoB decreased significantly in type IIa but increased in type IV hyperlipidaemia, which may reflect the presence of sialic acid in very low-density lipoprotein apolipoproteins other than apoB. N-Acetylneuraminic Acid 27-38 apolipoprotein B Homo sapiens 230-234 15989730-5 2005 CONCLUSION: The content of sialic acid in apoB decreased significantly in type IIa but increased in type IV hyperlipidaemia, which may reflect the presence of sialic acid in very low-density lipoprotein apolipoproteins other than apoB. N-Acetylneuraminic Acid 159-170 apolipoprotein B Homo sapiens 42-46 15989730-5 2005 CONCLUSION: The content of sialic acid in apoB decreased significantly in type IIa but increased in type IV hyperlipidaemia, which may reflect the presence of sialic acid in very low-density lipoprotein apolipoproteins other than apoB. N-Acetylneuraminic Acid 159-170 apolipoprotein B Homo sapiens 230-234 12927863-2 2003 Although apoB modification (cross-link and fragmentation) increases in atherosclerosis, the change in apoB-bound sialic acid in atherosclerosis is controversial. N-Acetylneuraminic Acid 113-124 apolipoprotein B Homo sapiens 102-106 12927863-5 2003 When human LDL was oxidized with Cu(2+) at 37 degrees C, apoB and apoB-attached sialic acid decreased simultaneously. N-Acetylneuraminic Acid 80-91 apolipoprotein B Homo sapiens 66-70 12927863-7 2003 In addition, human plasma was oxidized with 400 microM of Cu(2+) at 37 degrees C. Similar analysis indicates that the decrease in sialic acid attached to apoB also results from the fragmentation of apoB. N-Acetylneuraminic Acid 130-141 apolipoprotein B Homo sapiens 154-158 12927863-7 2003 In addition, human plasma was oxidized with 400 microM of Cu(2+) at 37 degrees C. Similar analysis indicates that the decrease in sialic acid attached to apoB also results from the fragmentation of apoB. N-Acetylneuraminic Acid 130-141 apolipoprotein B Homo sapiens 198-202 8864946-7 1996 These results suggest that in this population the sialic acid content of LDL was not associated with clinical signs of atherosclerosis, but the catabolic rate of dense LDL apoB was positively related to the sialic acid content of the respective lipoproteins. N-Acetylneuraminic Acid 207-218 apolipoprotein B Homo sapiens 172-176 10884293-4 2000 The LDL sialic acid ratio was inversely associated with respective lipid and apoB concentrations and positively with lipid-to-apoB ratios of LDL. N-Acetylneuraminic Acid 8-19 apolipoprotein B Homo sapiens 77-81 10884293-4 2000 The LDL sialic acid ratio was inversely associated with respective lipid and apoB concentrations and positively with lipid-to-apoB ratios of LDL. N-Acetylneuraminic Acid 8-19 apolipoprotein B Homo sapiens 126-130 10884293-5 2000 The transport rates (TRs) for total and dense LDL apoB were negatively associated with their sialic acid ratios. N-Acetylneuraminic Acid 93-104 apolipoprotein B Homo sapiens 50-54 10884293-8 2000 In conclusion, a low LDL sialic acid ratio was associated with CAD, high numbers of small LDL particles, and a high TR for LDL apoB, and in dense LDL also with high synthesis and low absorption of cholesterol. N-Acetylneuraminic Acid 25-36 apolipoprotein B Homo sapiens 127-131 10936670-10 2000 Significant correlations were found between serum total sialic acid concentrations and such cardiovascular risk factors as plasma levels of apolipoprotein B, low density lipoprotein cholesterol, triglycerides and uric acid in the diabetic subjects. N-Acetylneuraminic Acid 56-67 apolipoprotein B Homo sapiens 140-156 8864946-4 1996 Fractional catabolic rate (FCR) for LDL apoB was significantly faster in the diabetics than in the non-diabetics, and was positively associated with the sialic acid ratio in the total and dense LDL. N-Acetylneuraminic Acid 153-164 apolipoprotein B Homo sapiens 40-44 7507325-4 1993 Total sialic acid concentration correlated significantly with apolipoprotein B (r = 0.48), number of cigarettes smoked daily (r = 0.32), and leisure time physical activity (r = -0.23) after adjustment for age and other cardiovascular risk markers. N-Acetylneuraminic Acid 6-17 apolipoprotein B Homo sapiens 62-78