PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9013560-4	1997	However, PAH induction of ALDH-3 activity, protein, and mRNA was potentiated 2-4-fold by addition of the protein kinase A (PKA) inhibitors, N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide di-HCl (H8) and N-(2-guanidinoethyl)-5-isoquinolinesulfonamide HCl (HA1004).	Polycyclic Aromatic Hydrocarbons	9-12	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	105-121	
9013560-4	1997	However, PAH induction of ALDH-3 activity, protein, and mRNA was potentiated 2-4-fold by addition of the protein kinase A (PKA) inhibitors, N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide di-HCl (H8) and N-(2-guanidinoethyl)-5-isoquinolinesulfonamide HCl (HA1004).	Polycyclic Aromatic Hydrocarbons	9-12	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	123-126	
9013560-6	1997	Protein kinase A activity of cultured hepatocytes was specifically inhibited by H8 and HA1004 in a concentration-dependent manner, but not by H7, and there was an inverse correlation observed between potentiation of PAH-induced aldh3 gene expression and inhibition of specific PKA activity by the PKA inhibitors.	Polycyclic Aromatic Hydrocarbons	216-219	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	0-16	
9013560-6	1997	Protein kinase A activity of cultured hepatocytes was specifically inhibited by H8 and HA1004 in a concentration-dependent manner, but not by H7, and there was an inverse correlation observed between potentiation of PAH-induced aldh3 gene expression and inhibition of specific PKA activity by the PKA inhibitors.	Polycyclic Aromatic Hydrocarbons	216-219	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	277-280	
9013560-6	1997	Protein kinase A activity of cultured hepatocytes was specifically inhibited by H8 and HA1004 in a concentration-dependent manner, but not by H7, and there was an inverse correlation observed between potentiation of PAH-induced aldh3 gene expression and inhibition of specific PKA activity by the PKA inhibitors.	Polycyclic Aromatic Hydrocarbons	216-219	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	297-300