PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22167199-9	2012	This beta2ADR-dependent signaling pathway activated by PAHs may likely be crucial for PAH-mediated up-regulation of AhR target genes, thus suggesting a contribution of beta2ADR to the health-threatening effects of these environmental pollutants.	Polycyclic Aromatic Hydrocarbons	55-58	adrenoceptor beta 2	Homo sapiens	5-13	
22167199-9	2012	This beta2ADR-dependent signaling pathway activated by PAHs may likely be crucial for PAH-mediated up-regulation of AhR target genes, thus suggesting a contribution of beta2ADR to the health-threatening effects of these environmental pollutants.	Polycyclic Aromatic Hydrocarbons	55-58	adrenoceptor beta 2	Homo sapiens	168-176	
21617201-5	2011	We hypothesized that exposure to PAH might similarly interfere with the function of beta(2)AR in airway epithelial or smooth muscle cells, reducing the efficacy of a medication important for the treatment of asthma symptoms.	Polycyclic Aromatic Hydrocarbons	33-36	adrenoceptor beta 2	Homo sapiens	84-93	
21617201-8	2011	Murine tracheal epithelial cells and human airway smooth muscle cells, after exposure to a PAH mixture, exhibited reduced expression and function of beta(2)AR.	Polycyclic Aromatic Hydrocarbons	91-94	adrenoceptor beta 2	Homo sapiens	149-158	
21617201-9	2011	These findings support our hypothesis that environmentally relevant PAHs can impede beta(2)AR-mediated airway relaxation, and suggest a new paradigm where air pollutants not only contribute to the pathogenesis of childhood asthma, but also diminish responsiveness to standard therapy.	Polycyclic Aromatic Hydrocarbons	68-72	adrenoceptor beta 2	Homo sapiens	84-93