PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24837322-3 2014 The BaP played a dominant role for carcinogenic and mutagenic potencies of PAHs, although the IND showed the highest concentration level. Polycyclic Aromatic Hydrocarbons 75-79 prohibitin 2 Homo sapiens 4-7 25411724-1 2014 Cigarette smoke is a known source of exposure to carcinogenic polycyclic aromatic hydrocarbons (PAHs), especially benzo[a]pyrene (BaP). Polycyclic Aromatic Hydrocarbons 62-94 prohibitin 2 Homo sapiens 130-133 25411724-1 2014 Cigarette smoke is a known source of exposure to carcinogenic polycyclic aromatic hydrocarbons (PAHs), especially benzo[a]pyrene (BaP). Polycyclic Aromatic Hydrocarbons 96-100 prohibitin 2 Homo sapiens 130-133 24601014-2 2013 We report here a study of the effect of bulk diffusivity of polycyclic aromatic hydrocarbons (PAHs) in secondary organic aerosol (SOA) on the kinetics of the heterogeneous reaction of particle-borne benzo[a]pyrene (BaP) with ozone. Polycyclic Aromatic Hydrocarbons 60-92 prohibitin 2 Homo sapiens 215-218 24892667-1 2013 OBJECTIVE: Quantifying polycyclic aromatic hydrocarbon levels in urine samples taken from a population of traffic police working in the metropolitan area of Bogota who were occupationally exposed to 1-hydroxypyrene (1-OHP) and 3-hydroxy-benzo[a]pyrene (3-BaP) metabolites from polycyclic aromatic hydrocarbons (PAH) having toxicological interest, related to their detection, and a degree of exposure to particulate material having a size less than 10 micrometres (PM10) and/or other factors. Polycyclic Aromatic Hydrocarbons 23-54 prohibitin 2 Homo sapiens 255-258 22661331-0 2013 Promoting the use of BaP as a marker for PAH exposure in UK soils. Polycyclic Aromatic Hydrocarbons 41-44 prohibitin 2 Homo sapiens 21-24 22661331-11 2013 Using all data, highly significant correlations were seen between BaP and other carcinogenic PAH with the majority of r (2) values > 0.8. Polycyclic Aromatic Hydrocarbons 93-96 prohibitin 2 Homo sapiens 66-69 22661331-13 2013 We therefore conclude that BaP is a suitable surrogate marker to represent mixtures of PAH in soil during risk assessments. Polycyclic Aromatic Hydrocarbons 87-90 prohibitin 2 Homo sapiens 27-30 24601014-2 2013 We report here a study of the effect of bulk diffusivity of polycyclic aromatic hydrocarbons (PAHs) in secondary organic aerosol (SOA) on the kinetics of the heterogeneous reaction of particle-borne benzo[a]pyrene (BaP) with ozone. Polycyclic Aromatic Hydrocarbons 94-98 prohibitin 2 Homo sapiens 215-218 22805987-2 2013 Exposure to carcinogenic polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP), may have a role in this increased risk. Polycyclic Aromatic Hydrocarbons 25-57 prohibitin 2 Homo sapiens 90-93 22805987-2 2013 Exposure to carcinogenic polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP), may have a role in this increased risk. Polycyclic Aromatic Hydrocarbons 59-63 prohibitin 2 Homo sapiens 90-93 21452393-1 2012 Polycyclic aromatic hydrocarbons (PAHs) such as benzo(a)pyrene (B(a)P) constitute a major family of widely-distributed environmental toxic contaminants, known as potent ligands of the aryl hydrocarbon receptor (AhR). Polycyclic Aromatic Hydrocarbons 0-32 prohibitin 2 Homo sapiens 64-69 21452393-1 2012 Polycyclic aromatic hydrocarbons (PAHs) such as benzo(a)pyrene (B(a)P) constitute a major family of widely-distributed environmental toxic contaminants, known as potent ligands of the aryl hydrocarbon receptor (AhR). Polycyclic Aromatic Hydrocarbons 34-38 prohibitin 2 Homo sapiens 64-69 23019814-2 2012 The study permitted to identify the coke oven as the main PAH source in Genoa, causing constant exceeding of benzo(a)pyrene (BaP) air quality target (1.0 ng/m3) in the urban area till 1,900 meters distance downwind the plant. Polycyclic Aromatic Hydrocarbons 58-61 prohibitin 2 Homo sapiens 125-128 21645723-1 2011 Benzo[a]pyrene (BaP), a member of the polycyclic aromatic hydrocarbon (PAH) class, is one of the most potent PAH carcinogens. Polycyclic Aromatic Hydrocarbons 38-69 prohibitin 2 Homo sapiens 16-19 21897389-6 2011 RESULTS: The risk of RCC increased with intake of barbecued meat (P(trend)=0.04) and the PAH, benzo(a)pyrene (BaP) (multivariable-adjusted odds ratio and 95% confidence interval, highest vs lowest quartile: 1.50 (1.14, 1.95), P(trend)=0.001). Polycyclic Aromatic Hydrocarbons 89-92 prohibitin 2 Homo sapiens 110-113 21897389-9 2011 CONCLUSION: BaP intake, a PAH in barbecued meat, was positively associated with RCC. Polycyclic Aromatic Hydrocarbons 26-29 prohibitin 2 Homo sapiens 12-15 22139300-9 2012 Since Tibetan women typically spend longer time within the tents, they were exposed to PAHs (BaP exposure = 1.81 mug/m(3)) about two times of other family members. Polycyclic Aromatic Hydrocarbons 87-91 prohibitin 2 Homo sapiens 93-96 22139300-10 2012 Among all the PAHs, Bap contributed the most (82.6%) of the total carcinogenicity. Polycyclic Aromatic Hydrocarbons 14-18 prohibitin 2 Homo sapiens 20-23 22120587-2 2012 Benzo[a]pyrene (BaP) is genotoxic and is a prototype of PAH carcinogens. Polycyclic Aromatic Hydrocarbons 56-59 prohibitin 2 Homo sapiens 16-19 22225155-3 2011 Similar to pyrene, another peri-condensed polycyclic aromatic hydrocarbon we have investigated, the first two electronically excited states of BaP exhibit extensive configuration interactions. Polycyclic Aromatic Hydrocarbons 42-73 prohibitin 2 Homo sapiens 143-146 22202470-3 2011 Because some PAHs such as Benzo[a]pyrene (BaP) are proven carcinogens and mutagens, it is necessary to continuously monitor their concentrations in the air, water, and soil. Polycyclic Aromatic Hydrocarbons 13-17 prohibitin 2 Homo sapiens 42-45 21911031-1 2011 Polycyclic aromatic hydrocarbons (PAHs), such as benzo(a)pyrene (BaP), are widely distributed toxic environmental contaminants well known to regulate gene expression through activation of the aryl hydrocarbon receptor (AhR). Polycyclic Aromatic Hydrocarbons 0-32 prohibitin 2 Homo sapiens 65-68 21911031-1 2011 Polycyclic aromatic hydrocarbons (PAHs), such as benzo(a)pyrene (BaP), are widely distributed toxic environmental contaminants well known to regulate gene expression through activation of the aryl hydrocarbon receptor (AhR). Polycyclic Aromatic Hydrocarbons 34-38 prohibitin 2 Homo sapiens 65-68 21911031-5 2011 Three-methylcholanthrene, a PAH known to activate AhR like BaP, induced FcalphaRI expression, in contrast to benzo(e)pyrene, a PAH known to poorly interact with AhR. Polycyclic Aromatic Hydrocarbons 28-31 prohibitin 2 Homo sapiens 59-62 21478082-6 2011 We used toxic equivalence factors to calculate benzo[a]pyrene (BaP) equivalents (BaP-eq) for individual PAHs and applied the World Health Organization unit risk (UR) for BaP (UR = 8.7 x 10-5) to estimate lifetime cancer risks due to PAH exposures. Polycyclic Aromatic Hydrocarbons 104-108 prohibitin 2 Homo sapiens 63-66 21478082-6 2011 We used toxic equivalence factors to calculate benzo[a]pyrene (BaP) equivalents (BaP-eq) for individual PAHs and applied the World Health Organization unit risk (UR) for BaP (UR = 8.7 x 10-5) to estimate lifetime cancer risks due to PAH exposures. Polycyclic Aromatic Hydrocarbons 104-107 prohibitin 2 Homo sapiens 63-66 21478082-8 2011 The contribution of gas-phase PAHs to the total BaP-eq value was between 34% and 86%. Polycyclic Aromatic Hydrocarbons 30-34 prohibitin 2 Homo sapiens 48-51 21645723-1 2011 Benzo[a]pyrene (BaP), a member of the polycyclic aromatic hydrocarbon (PAH) class, is one of the most potent PAH carcinogens. Polycyclic Aromatic Hydrocarbons 71-74 prohibitin 2 Homo sapiens 16-19 21645723-1 2011 Benzo[a]pyrene (BaP), a member of the polycyclic aromatic hydrocarbon (PAH) class, is one of the most potent PAH carcinogens. Polycyclic Aromatic Hydrocarbons 109-112 prohibitin 2 Homo sapiens 16-19 21146218-1 2011 Both the World Health Organization and the UK Expert Panel on Air Quality Standards (EPAQS) have considered benzo(a)pyrene (BaP) as a marker of the carcinogenic potency of the polycyclic aromatic hydrocarbons (PAH) mixture, when recommending their respective guidelines for PAHs in outdoor air. Polycyclic Aromatic Hydrocarbons 210-213 prohibitin 2 Homo sapiens 124-127 21146218-1 2011 Both the World Health Organization and the UK Expert Panel on Air Quality Standards (EPAQS) have considered benzo(a)pyrene (BaP) as a marker of the carcinogenic potency of the polycyclic aromatic hydrocarbons (PAH) mixture, when recommending their respective guidelines for PAHs in outdoor air. Polycyclic Aromatic Hydrocarbons 274-278 prohibitin 2 Homo sapiens 124-127 21146218-7 2011 The relative contribution of BaP to the PAH overall carcinogenic potency is similar indoors (49%), outdoors (54%) and in the smelter environment (48%) used by EPAQS to derive the UK Air Quality Standard for ambient air. Polycyclic Aromatic Hydrocarbons 40-43 prohibitin 2 Homo sapiens 29-32 21146218-8 2011 These results suggest the suitability of BaP as a marker for the carcinogenic potential of the PAH mixture irrespective of the environment. Polycyclic Aromatic Hydrocarbons 95-98 prohibitin 2 Homo sapiens 41-44 21286013-1 2011 Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is easily introduced to humans via consumption of grilled or smoked meat. Polycyclic Aromatic Hydrocarbons 26-57 prohibitin 2 Homo sapiens 16-19 21286013-1 2011 Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is easily introduced to humans via consumption of grilled or smoked meat. Polycyclic Aromatic Hydrocarbons 59-62 prohibitin 2 Homo sapiens 16-19 20674550-4 2010 In a genome-wide P450 microarray screen, we identified six PAH-responsive P450 genes (Pc-pah1-Pc-pah6) inducible by PAHs of varying ring size, namely naphthalene, phenanthrene, pyrene, and benzo(a)pyrene (BaP). Polycyclic Aromatic Hydrocarbons 59-62 prohibitin 2 Homo sapiens 205-208 20674550-4 2010 In a genome-wide P450 microarray screen, we identified six PAH-responsive P450 genes (Pc-pah1-Pc-pah6) inducible by PAHs of varying ring size, namely naphthalene, phenanthrene, pyrene, and benzo(a)pyrene (BaP). Polycyclic Aromatic Hydrocarbons 116-120 prohibitin 2 Homo sapiens 205-208 20064835-7 2010 AhR and p53 implications were moreover fully confirmed by the prevention of BaP-related upregulation of some selected target genes by AhR silencing or the use of pifithrin-alpha, an inhibitor of PAH bioactivation-related DNA damage/p53 pathways. Polycyclic Aromatic Hydrocarbons 195-198 prohibitin 2 Homo sapiens 76-79 20064835-2 2010 In order to identify their molecular targets in such cells, we have analyzed gene expression profile of primary human macrophages treated by the prototypical PAH benzo(a)pyrene (BaP), using pangenomic oligonucleotides microarrays. Polycyclic Aromatic Hydrocarbons 158-161 prohibitin 2 Homo sapiens 178-181 20064835-6 2010 Their bioinformatic analysis indicated that biological functions linked to immunity, inflammation, and cell death were among the most affected by BaP in human macrophages and that the AhR and p53 signaling pathways were the most significant canonical pathways activated by the PAH. Polycyclic Aromatic Hydrocarbons 277-280 prohibitin 2 Homo sapiens 146-149 24031437-1 2009 Benzo [a] Pyrene (BaP) is a highly recalcitrant, polycyclic aromatic hydrocarbon (PAH) with high genotoxicity and carcinogenicity. Polycyclic Aromatic Hydrocarbons 49-80 prohibitin 2 Homo sapiens 18-21 19950922-3 2010 Accumulation of the polycyclic aromatic hydrocarbons (PAHs) naphthalene (Nap), phenanthrene (Phe), pyrene (Pyr), and benz(a)pyrene (Bap) by PECAM was compared with their uptake by plants. Polycyclic Aromatic Hydrocarbons 20-52 prohibitin 2 Homo sapiens 132-135 24031437-1 2009 Benzo [a] Pyrene (BaP) is a highly recalcitrant, polycyclic aromatic hydrocarbon (PAH) with high genotoxicity and carcinogenicity. Polycyclic Aromatic Hydrocarbons 82-85 prohibitin 2 Homo sapiens 18-21 19463884-1 2009 Pyrene, benzo[a]pyrene (BaP), and indeno[1,2,3-cd]pyrene (IND) are poly cyclic aromatic hydrocarbons (PAHs) with four to six annealed phenyl rings. Polycyclic Aromatic Hydrocarbons 67-100 prohibitin 2 Homo sapiens 24-27 19463884-1 2009 Pyrene, benzo[a]pyrene (BaP), and indeno[1,2,3-cd]pyrene (IND) are poly cyclic aromatic hydrocarbons (PAHs) with four to six annealed phenyl rings. Polycyclic Aromatic Hydrocarbons 102-106 prohibitin 2 Homo sapiens 24-27 18204078-1 2008 Many studies using mammalian cellular and subcellular systems have demonstrated that polycyclic aromatic hydrocarbons, including benzo[a]pyrene (BaP), are metabolically activated by cytochrome P450s (CYPs). Polycyclic Aromatic Hydrocarbons 85-117 prohibitin 2 Homo sapiens 145-148 22063352-5 2008 BaP comprises in general 4.6% of the total sum of the 16 EU priority PAHs and 15.2% of the total sum of the 12 IARC PAH compounds. Polycyclic Aromatic Hydrocarbons 69-72 prohibitin 2 Homo sapiens 0-3 18839584-8 2008 The concentration of BaP, a strong carcinogenic PAH, was found in sludge with 0-2.20 mg x kg(-1) and the average of 0.15 mg x kg(-1), which was much less than 3.0 mg x kg(-1) of the control standard of sludge land application. Polycyclic Aromatic Hydrocarbons 48-51 prohibitin 2 Homo sapiens 21-24 18754350-5 2008 The total PAH cancer potency (sum of BaP equivalents) was significantly higher (about 4 times) in the wood-burning homes compared with the reference homes, with BaP being the largest contributor, while phenanthrene made the largest contribution to the total PAH concentration in indoor and outdoor air. Polycyclic Aromatic Hydrocarbons 10-13 prohibitin 2 Homo sapiens 37-40 17449565-2 2008 In this context, the analytical and diagnostical reliability of 3-hydroxybenzo[a]pyrene (3OH-BaP) as a biomarker of internal exposure to PAHs was established. Polycyclic Aromatic Hydrocarbons 137-141 prohibitin 2 Homo sapiens 93-96 18560987-9 2009 The BaP and relative BaP amount calculated from the measurements suggested that photo-oxidation may also be responsible for the variation in PAH concentrations during winter and summer. Polycyclic Aromatic Hydrocarbons 141-144 prohibitin 2 Homo sapiens 21-24 18255148-10 2008 Although annual averages for BaP did not exceed the limit value, autumn and winter BaP mass concentrations did, which calls for measures for reducing PAH emissions in the autumn and winter. Polycyclic Aromatic Hydrocarbons 150-153 prohibitin 2 Homo sapiens 83-86 16906435-15 2007 Hence, human exposure to PAH mixtures with high content of BaP-type hydrocarbons confers a potentially higher health risk than PAH mixtures with low content of procarcinogens. Polycyclic Aromatic Hydrocarbons 25-28 prohibitin 2 Homo sapiens 59-62 17253627-1 2007 Benzo[a]pyrene (BaP) is listed as a priority pollutant by the U.S. Environmental Protection Agency because it is one of the most potent carcinogens of all known polycyclic aromatic hydrocarbons (PAHs). Polycyclic Aromatic Hydrocarbons 161-193 prohibitin 2 Homo sapiens 16-19 17253627-1 2007 Benzo[a]pyrene (BaP) is listed as a priority pollutant by the U.S. Environmental Protection Agency because it is one of the most potent carcinogens of all known polycyclic aromatic hydrocarbons (PAHs). Polycyclic Aromatic Hydrocarbons 195-199 prohibitin 2 Homo sapiens 16-19 15740759-8 2005 A virtually safe oral dose of BaP, as a marker of the carcinogenic PAH, was suggested by a European expert commission to be below 4.2 to 35 ng per person and day. Polycyclic Aromatic Hydrocarbons 67-70 prohibitin 2 Homo sapiens 30-33 17308111-9 2007 Taken together, our findings suggest that, on BaP exposure, MKK4/JNK targets NHE1 with consequences on HKII protein, which might thus be a key protein during carcinogenic PAH apoptosis. Polycyclic Aromatic Hydrocarbons 171-174 prohibitin 2 Homo sapiens 46-49 17285163-6 2007 Toxic potency assessment of soil PAHs presented a good relationship with benzo(a)pyrene (BaP) levels, toxic equivalent concentrations based on BaP (TEQ(BaP)) and dioxin-like toxic equivalent concentrations (TEQ(TCDD)). Polycyclic Aromatic Hydrocarbons 33-37 prohibitin 2 Homo sapiens 89-92 17285163-6 2007 Toxic potency assessment of soil PAHs presented a good relationship with benzo(a)pyrene (BaP) levels, toxic equivalent concentrations based on BaP (TEQ(BaP)) and dioxin-like toxic equivalent concentrations (TEQ(TCDD)). Polycyclic Aromatic Hydrocarbons 33-37 prohibitin 2 Homo sapiens 143-146 17285163-6 2007 Toxic potency assessment of soil PAHs presented a good relationship with benzo(a)pyrene (BaP) levels, toxic equivalent concentrations based on BaP (TEQ(BaP)) and dioxin-like toxic equivalent concentrations (TEQ(TCDD)). Polycyclic Aromatic Hydrocarbons 33-37 prohibitin 2 Homo sapiens 143-146 17285163-7 2007 The study highlights that BaP is a good indicator for assessing the potential toxicity of PAHs, and presents a promising toxicity assessment method for soil PAHs. Polycyclic Aromatic Hydrocarbons 90-94 prohibitin 2 Homo sapiens 26-29 16751148-2 2006 BaP is often taken as an indicator of the presence of polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons 54-86 prohibitin 2 Homo sapiens 0-3 16551675-8 2006 Airborne benzo(a)pyrene (BaP) correlated well (r(2) = 0.971) with levels of carcinogenic 4-6 ring PAHs and was an effective marker of exposure for all industries where significant particle bound PAH levels were found and, in particular, for CTPV exposure. Polycyclic Aromatic Hydrocarbons 98-102 prohibitin 2 Homo sapiens 25-28 16551675-8 2006 Airborne benzo(a)pyrene (BaP) correlated well (r(2) = 0.971) with levels of carcinogenic 4-6 ring PAHs and was an effective marker of exposure for all industries where significant particle bound PAH levels were found and, in particular, for CTPV exposure. Polycyclic Aromatic Hydrocarbons 98-101 prohibitin 2 Homo sapiens 25-28 16392842-7 2006 The geometrical distortions of the BaP structure upon nitro group substitution and correlations between structural parameters and vibrational data as well as structure-function relationships related to the mutagenicity of this important class of polycyclic aromatic hydrocarbons are discussed. Polycyclic Aromatic Hydrocarbons 246-278 prohibitin 2 Homo sapiens 35-38 15856074-11 2005 Detectable PAH-DNA adducts were inversely associated with increased BaP levels in dust in the home, but positively associated with BaP levels in soil outside of the home, although CIs were wide. Polycyclic Aromatic Hydrocarbons 11-14 prohibitin 2 Homo sapiens 68-71 15856074-11 2005 Detectable PAH-DNA adducts were inversely associated with increased BaP levels in dust in the home, but positively associated with BaP levels in soil outside of the home, although CIs were wide. Polycyclic Aromatic Hydrocarbons 11-14 prohibitin 2 Homo sapiens 131-134 15548639-1 2005 Polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP), are carcinogens suggested to be involved in development of human cancer. Polycyclic Aromatic Hydrocarbons 0-32 prohibitin 2 Homo sapiens 65-68 15548639-1 2005 Polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP), are carcinogens suggested to be involved in development of human cancer. Polycyclic Aromatic Hydrocarbons 34-38 prohibitin 2 Homo sapiens 65-68 15548639-4 2005 In the present study, we found that two PAHs, benz[a]anthracene (BaA) and BaP, can stimulate proliferation of human breast carcinoma MCF-7 cells at concentrations 100 nM and higher. Polycyclic Aromatic Hydrocarbons 40-44 prohibitin 2 Homo sapiens 74-77 7508716-3 1993 Taking 1.5 as a borderline value for the BghiPer/BaP ratio, a significant influence of car traffic on air pollution by polycyclic aromatic hydrocarbons was noticed at a site close to a petrol station. Polycyclic Aromatic Hydrocarbons 119-151 prohibitin 2 Homo sapiens 49-52 15315710-1 2004 BACKGROUND: Benzo(a)pyrene (BaP), anthracene (ANTH) and chrysene (CHRY) are polynuclear aromatic hydrocarbons (PAHs) implicated in renal toxicity and carcinogenesis. Polycyclic Aromatic Hydrocarbons 76-109 prohibitin 2 Homo sapiens 28-31 15315710-1 2004 BACKGROUND: Benzo(a)pyrene (BaP), anthracene (ANTH) and chrysene (CHRY) are polynuclear aromatic hydrocarbons (PAHs) implicated in renal toxicity and carcinogenesis. Polycyclic Aromatic Hydrocarbons 111-115 prohibitin 2 Homo sapiens 28-31 14740720-6 2004 Inhalation risk associated with carcinogenic PAHs was estimated by using toxic equivalency factors based on the potency of benzo[a]pyrene (BaP). Polycyclic Aromatic Hydrocarbons 45-49 prohibitin 2 Homo sapiens 139-142 14740720-7 2004 The carcinogenicity of the indoor PAH mixture was dominated by naphthalene followed by BaP and dibenz[a,h]anthracene. Polycyclic Aromatic Hydrocarbons 34-37 prohibitin 2 Homo sapiens 87-90 11448646-9 2001 The results of the present study show that MK amplifies the genotoxic effects of B(a)P in human derived cells and indicate that exposure of humans to MK might increase their susceptibility to the health hazards of B(a)P and other polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons 230-262 prohibitin 2 Homo sapiens 81-86 11408366-4 2001 Cells rapidly took up PAHs (BAP, BKF) from medium; by 24 h only 14% remained in the medium, and no detectable PAH bound to well walls. Polycyclic Aromatic Hydrocarbons 22-26 prohibitin 2 Homo sapiens 28-31 9920462-9 1998 This study further confirms the usefulness of BPDE-DNA adduct levels determination in the lungs from autopsy samples for monitoring long-term human exposure to BaP, a representative PAH. Polycyclic Aromatic Hydrocarbons 182-185 prohibitin 2 Homo sapiens 160-163 15563282-2 2004 Because compounds with the highest toxicity, such as dibenz(a,h)anthracene and benzo(a)pyrene (BAP), also tended to be the least rapidly and least extensively desorbed, the U.S. Environmental Protection Agency (EPA) default guidance may dramatically overestimate risk from exposure to PAH-contaminated soils or sediments. Polycyclic Aromatic Hydrocarbons 285-288 prohibitin 2 Homo sapiens 95-98 12619281-2 2002 This paper dealed with the effects of some polycyclic aromatic hydrocarbons (PAHs) and two kinds of monoaromatics on the degradation of BaP. Polycyclic Aromatic Hydrocarbons 43-75 prohibitin 2 Homo sapiens 136-139 12619281-2 2002 This paper dealed with the effects of some polycyclic aromatic hydrocarbons (PAHs) and two kinds of monoaromatics on the degradation of BaP. Polycyclic Aromatic Hydrocarbons 77-81 prohibitin 2 Homo sapiens 136-139 11965528-12 2002 These results confirm the common practice to use BaP as marker compound for the PAH exposure in ambient air. Polycyclic Aromatic Hydrocarbons 80-83 prohibitin 2 Homo sapiens 49-52 9920462-1 1998 Benzo[a]pyrene (BaP) and other polycyclic aromatic hydrocarbons (PAHs) which are present in cigarette smoke, are common air and food genotoxic contaminants and possible human carcinogens. Polycyclic Aromatic Hydrocarbons 31-63 prohibitin 2 Homo sapiens 16-19 9920462-1 1998 Benzo[a]pyrene (BaP) and other polycyclic aromatic hydrocarbons (PAHs) which are present in cigarette smoke, are common air and food genotoxic contaminants and possible human carcinogens. Polycyclic Aromatic Hydrocarbons 65-69 prohibitin 2 Homo sapiens 16-19 8806850-5 1996 Our results using human lymphocytes differed from previous studies in rodents, in that BaP and 3-MC were the most immunotoxic PAHs in the human mitogenesis assay, while DMBA has long been regarded as the PAH that is most potently toxic to rodent T cell responses. Polycyclic Aromatic Hydrocarbons 126-130 prohibitin 2 Homo sapiens 87-90 8806850-5 1996 Our results using human lymphocytes differed from previous studies in rodents, in that BaP and 3-MC were the most immunotoxic PAHs in the human mitogenesis assay, while DMBA has long been regarded as the PAH that is most potently toxic to rodent T cell responses. Polycyclic Aromatic Hydrocarbons 126-129 prohibitin 2 Homo sapiens 87-90 35209168-1 2022 Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) primarily formed by burning of fossil fuels, wood and other organic materials. Polycyclic Aromatic Hydrocarbons 26-57 prohibitin 2 Homo sapiens 16-19 35199223-1 2022 Benzo(a)pyrene (BaP) is a high molecular weight polycyclic aromatic hydrocarbon produced as a result of incomplete combustion of organic substances. Polycyclic Aromatic Hydrocarbons 48-79 prohibitin 2 Homo sapiens 16-19 35209168-1 2022 Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) primarily formed by burning of fossil fuels, wood and other organic materials. Polycyclic Aromatic Hydrocarbons 59-62 prohibitin 2 Homo sapiens 16-19 32265041-1 2020 Diet is a major source of human exposure to polycyclic aromatic hydrocarbons (PAHs), of which benzo[a]pyrene (BaP) is the most commonly studied and measured. Polycyclic Aromatic Hydrocarbons 44-76 prohibitin 2 Homo sapiens 110-113 3415236-9 1988 Photolysis of BaP and similar PAH compounds represents a useful treatment option that could be applied to certain PAH-containing petroleum refinery sludge and to coal tar residues in order to facilitate their detoxification and environmentally safe disposal. Polycyclic Aromatic Hydrocarbons 114-117 prohibitin 2 Homo sapiens 14-17 32265041-1 2020 Diet is a major source of human exposure to polycyclic aromatic hydrocarbons (PAHs), of which benzo[a]pyrene (BaP) is the most commonly studied and measured. Polycyclic Aromatic Hydrocarbons 78-82 prohibitin 2 Homo sapiens 110-113 32841893-1 2020 Environmental carcinogen benzo(a)pyrene (BaP) is a representative compound of polycyclic aromatic hydrocarbons (PAHs). Polycyclic Aromatic Hydrocarbons 78-110 prohibitin 2 Homo sapiens 41-44 32841893-1 2020 Environmental carcinogen benzo(a)pyrene (BaP) is a representative compound of polycyclic aromatic hydrocarbons (PAHs). Polycyclic Aromatic Hydrocarbons 112-116 prohibitin 2 Homo sapiens 41-44 29750188-1 2018 Polycyclic aromatic hydrocarbons like benzo(a)pyrene (BaP) in atmospheric particulate matter pose a threat to human health because of their high carcinogenicity. Polycyclic Aromatic Hydrocarbons 0-32 prohibitin 2 Homo sapiens 54-57 30553920-7 2019 Our results indicate that the combined effect of pairwise PAHs of BaP with Benzo[b]fluoranthene (BbF) and Benz[a]anthracene (BaA) is synergistic on p53 pathway, and that the health risk of the such mixtures increases compared to that of the individual ones. Polycyclic Aromatic Hydrocarbons 58-62 prohibitin 2 Homo sapiens 66-69 29471073-1 2018 Polycyclic aromatic hydrocarbons such as benzo[a]pyrene (BaP) can induce cytochrome P450 1A1 (CYP1A1) via a p53-dependent mechanism. Polycyclic Aromatic Hydrocarbons 0-32 prohibitin 2 Homo sapiens 57-60 31763181-10 2019 These data suggest that the mixture of PAHs is more toxic and perturbing to DNA synthesis than BaP alone in cultured cells, and the toxicity is accompanied by NOX2 activation. Polycyclic Aromatic Hydrocarbons 39-43 prohibitin 2 Homo sapiens 95-98 31142653-1 2019 Benzo[a]pyrene (BaP), a key polycyclic aromatic hydrocarbon (PAH) often associated with soot particles coated by organic compounds, is a known carcinogen and mutagen. Polycyclic Aromatic Hydrocarbons 28-59 prohibitin 2 Homo sapiens 16-19 31142653-1 2019 Benzo[a]pyrene (BaP), a key polycyclic aromatic hydrocarbon (PAH) often associated with soot particles coated by organic compounds, is a known carcinogen and mutagen. Polycyclic Aromatic Hydrocarbons 61-64 prohibitin 2 Homo sapiens 16-19 31142653-4 2019 Kinetic multilayer modeling demonstrates that the slow decay of BaP over long times can be simulated if there is slow diffusion of BaP from the film interior to the surface, resolving long-standing unresolved observations of incomplete PAH decay upon prolonged ozone exposure. Polycyclic Aromatic Hydrocarbons 236-239 prohibitin 2 Homo sapiens 64-67 31142653-4 2019 Kinetic multilayer modeling demonstrates that the slow decay of BaP over long times can be simulated if there is slow diffusion of BaP from the film interior to the surface, resolving long-standing unresolved observations of incomplete PAH decay upon prolonged ozone exposure. Polycyclic Aromatic Hydrocarbons 236-239 prohibitin 2 Homo sapiens 131-134 30419384-9 2019 Importantly, a decreasing trend of PAHs was observed in multimedia from 2012 to 2020 and the transfer flux from the air to vegetation to soil was the dominant pathways of BaP intermedia circulation processes. Polycyclic Aromatic Hydrocarbons 35-39 prohibitin 2 Homo sapiens 171-174 30142607-3 2018 Fluoranthene (Flt) was the most commonly occurring among the 16 priority PAHs, and benzo(a)pyrene (BaP) accounted for the largest portion of the total carcinogenic potency of PAHs in PM2.5. Polycyclic Aromatic Hydrocarbons 175-179 prohibitin 2 Homo sapiens 99-102 29758891-1 2018 The involvement of benzo[a]pyrene (BaP) one of the most toxic polycyclic aromatic hydrocarbons (PAHs) in the soil-plant system causes its potential carcinogenicity and mutagenicity for human health. Polycyclic Aromatic Hydrocarbons 62-94 prohibitin 2 Homo sapiens 35-38 29758891-1 2018 The involvement of benzo[a]pyrene (BaP) one of the most toxic polycyclic aromatic hydrocarbons (PAHs) in the soil-plant system causes its potential carcinogenicity and mutagenicity for human health. Polycyclic Aromatic Hydrocarbons 96-100 prohibitin 2 Homo sapiens 35-38 29486658-4 2018 The mean dietary exposure to PAHs was estimated at the levels of 5.4 ng BaP/kg bw/day and 36 ng PAH4/kg bw/day. Polycyclic Aromatic Hydrocarbons 29-33 prohibitin 2 Homo sapiens 72-75 27396317-3 2016 Naphthalene and BaP, were the dominant PAH species and potentially carcinogenic PAH species in the shallow groundwater of the study area, and they account for 89.97% of PAHs and 82.62% of PAHC7, respectively. Polycyclic Aromatic Hydrocarbons 39-42 prohibitin 2 Homo sapiens 16-19 28801749-2 2017 Published monitoring data of polycyclic aromatic hydrocarbons present in soils and sediments at different study points across India were collected and converted to their corresponding BaP equivalent concentrations. Polycyclic Aromatic Hydrocarbons 29-61 prohibitin 2 Homo sapiens 184-187 28115713-2 2017 One of the most carcinogenic PAHs, benzo(a)pyrene (BaP), is efficiently bound to and transported with atmospheric particles. Polycyclic Aromatic Hydrocarbons 29-33 prohibitin 2 Homo sapiens 51-54 29111668-1 2017 Benzo[a]pyrene (BaP), an archetypical polycyclic aromatic hydrocarbon, is classified as "carcinogenic to humans" and is ubiquitous in the environment, as evident by the measurable levels of BaP metabolites in virtually all human urine samples examined. Polycyclic Aromatic Hydrocarbons 38-69 prohibitin 2 Homo sapiens 16-19 27396317-3 2016 Naphthalene and BaP, were the dominant PAH species and potentially carcinogenic PAH species in the shallow groundwater of the study area, and they account for 89.97% of PAHs and 82.62% of PAHC7, respectively. Polycyclic Aromatic Hydrocarbons 80-83 prohibitin 2 Homo sapiens 16-19 27396317-3 2016 Naphthalene and BaP, were the dominant PAH species and potentially carcinogenic PAH species in the shallow groundwater of the study area, and they account for 89.97% of PAHs and 82.62% of PAHC7, respectively. Polycyclic Aromatic Hydrocarbons 170-174 prohibitin 2 Homo sapiens 16-19 27107589-6 2016 The results showed that concentrations of BaP, a PAH that serves as an indicator of PAH pollution, exceeded the Chinese national standard by 4-12 times. Polycyclic Aromatic Hydrocarbons 49-52 prohibitin 2 Homo sapiens 42-45 27107589-6 2016 The results showed that concentrations of BaP, a PAH that serves as an indicator of PAH pollution, exceeded the Chinese national standard by 4-12 times. Polycyclic Aromatic Hydrocarbons 84-87 prohibitin 2 Homo sapiens 42-45 27107589-8 2016 The toxic equivalents quantity (i.e., quantity of total PAHs with an equivalent toxicity to BaP) ranged from 13.35 to 22.54 ng/m(3) during the central heating period of winter and spring. Polycyclic Aromatic Hydrocarbons 56-60 prohibitin 2 Homo sapiens 92-95 25616380-8 2015 Estimated carcinogenicity of PAHs in terms of BaPeq indicated that BaP was the principal PAH contributor in CC (70%). Polycyclic Aromatic Hydrocarbons 29-32 prohibitin 2 Homo sapiens 46-49 25863370-9 2015 Because all other priority polycyclic aromatic hydrocarbons could not be electrochemically oxidized at 0.98 V, the electrochemical assay showed very high selectivity to BaP. Polycyclic Aromatic Hydrocarbons 27-59 prohibitin 2 Homo sapiens 169-172 26731659-2 2016 Benzo[a]pyrene (BaP), the most carcinogenic polycyclic aromatic hydrocarbon (PAH), is classified as a group 1 carcinogen by International Agency for Research on Cancer. Polycyclic Aromatic Hydrocarbons 44-75 prohibitin 2 Homo sapiens 16-19 26731659-2 2016 Benzo[a]pyrene (BaP), the most carcinogenic polycyclic aromatic hydrocarbon (PAH), is classified as a group 1 carcinogen by International Agency for Research on Cancer. Polycyclic Aromatic Hydrocarbons 77-80 prohibitin 2 Homo sapiens 16-19 30090347-2 2016 BaP is a polycyclic aromatic hydrocarbon generated by incomplete combustion of organic substances, thus contaminating numerous foodstuffs, and PhIP is a heterocyclic amine formed when meat is cooked. Polycyclic Aromatic Hydrocarbons 9-40 prohibitin 2 Homo sapiens 0-3