PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22028397-0	2012	CpG site-specific hypermethylation of p16INK4alpha in peripheral blood lymphocytes of PAH-exposed workers.	Polycyclic Aromatic Hydrocarbons	86-89	cyclin dependent kinase inhibitor 2A	Homo sapiens	38-50	
22028397-4	2012	Using bisulfite sequencing, we examined the methylation status of p16(INK4alpha) promoter in peripheral blood lymphocytes (PBL) from PAH-exposed workers and in benzo(a)pyrene (BaP)-transformed human bronchial epithelial (HBE) cells.	Polycyclic Aromatic Hydrocarbons	133-136	cyclin dependent kinase inhibitor 2A	Homo sapiens	66-69	
22028397-4	2012	Using bisulfite sequencing, we examined the methylation status of p16(INK4alpha) promoter in peripheral blood lymphocytes (PBL) from PAH-exposed workers and in benzo(a)pyrene (BaP)-transformed human bronchial epithelial (HBE) cells.	Polycyclic Aromatic Hydrocarbons	133-136	cyclin dependent kinase inhibitor 2A	Homo sapiens	70-79	
22028397-6	2012	RESULTS: Compared with the control group, PAH-exposed workers exhibited higher levels of urinary 1-OHP (10.62 vs. 2.52 mug/L), p16(INK4alpha) methylation (7.95% vs. 1.14% for 22 "hot" CpG sites), and CBMN (7.28% vs. 2.92%) in PBLs.	Polycyclic Aromatic Hydrocarbons	42-45	cyclin dependent kinase inhibitor 2A	Homo sapiens	127-130	
22028397-6	2012	RESULTS: Compared with the control group, PAH-exposed workers exhibited higher levels of urinary 1-OHP (10.62 vs. 2.52 mug/L), p16(INK4alpha) methylation (7.95% vs. 1.14% for 22 "hot" CpG sites), and CBMN (7.28% vs. 2.92%) in PBLs.	Polycyclic Aromatic Hydrocarbons	42-45	cyclin dependent kinase inhibitor 2A	Homo sapiens	131-140	
22028397-7	2012	p16(INK4alpha) hypermethylation in PAH-exposed workers exhibited CpG site specificity.	Polycyclic Aromatic Hydrocarbons	35-38	cyclin dependent kinase inhibitor 2A	Homo sapiens	0-3	
22028397-7	2012	p16(INK4alpha) hypermethylation in PAH-exposed workers exhibited CpG site specificity.	Polycyclic Aromatic Hydrocarbons	35-38	cyclin dependent kinase inhibitor 2A	Homo sapiens	4-13	
22028397-11	2012	CONCLUSION: PAH exposure induced CpG site-specific hypermethylation of p16(INK4alpha) gene.	Polycyclic Aromatic Hydrocarbons	12-15	cyclin dependent kinase inhibitor 2A	Homo sapiens	71-74	
22028397-11	2012	CONCLUSION: PAH exposure induced CpG site-specific hypermethylation of p16(INK4alpha) gene.	Polycyclic Aromatic Hydrocarbons	12-15	cyclin dependent kinase inhibitor 2A	Homo sapiens	75-84