PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24639079-4 2014 Pparbeta/delta-null keratinocytes exhibited decreased AHR occupancy and histone acetylation on the Cyp1a1 promoter in response to a PAH compared with wild-type keratinocytes. Polycyclic Aromatic Hydrocarbons 132-135 peroxisome proliferator activator receptor delta Mus musculus 0-8 24639079-9 2014 The mechanisms underlying this PPARbeta/delta-dependent reduction of AHR signaling by PAH are not due to alterations in the expression of AHR auxiliary proteins, ligand binding or AHR nuclear translocation between genotypes, but are likely influenced by PPARbeta/delta-dependent demethylation of AHR target gene promoters including Cyp1a1 that reduces AHR accessibility as shown by reduced promoter occupancy. Polycyclic Aromatic Hydrocarbons 86-89 peroxisome proliferator activator receptor delta Mus musculus 31-39 24639079-9 2014 The mechanisms underlying this PPARbeta/delta-dependent reduction of AHR signaling by PAH are not due to alterations in the expression of AHR auxiliary proteins, ligand binding or AHR nuclear translocation between genotypes, but are likely influenced by PPARbeta/delta-dependent demethylation of AHR target gene promoters including Cyp1a1 that reduces AHR accessibility as shown by reduced promoter occupancy. Polycyclic Aromatic Hydrocarbons 86-89 peroxisome proliferator activator receptor delta Mus musculus 254-262