PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31926616-3	2020	NO2-FA have been postulated as partial agonists of the Peroxisome Proliferator-Activated Receptor gamma (PPARgamma), which is predominantly expressed in adipocytes and myeloid cells.	Fluocinolone Acetonide	0-6	peroxisome proliferator activated receptor gamma	Homo sapiens	55-103	
31926616-3	2020	NO2-FA have been postulated as partial agonists of the Peroxisome Proliferator-Activated Receptor gamma (PPARgamma), which is predominantly expressed in adipocytes and myeloid cells.	Fluocinolone Acetonide	0-6	peroxisome proliferator activated receptor gamma	Homo sapiens	105-114	
31926616-4	2020	Herein, we explored molecular and cellular events associated with PPARgamma activation by NO2-FA in monocytes and macrophages.	Fluocinolone Acetonide	90-96	peroxisome proliferator activated receptor gamma	Homo sapiens	66-75	
31926616-5	2020	NO2-FA induced the expression of two PPARgamma reporter genes, Fatty Acid Binding Protein 4 (FABP4) and the scavenger receptor CD36, at early stages of monocyte differentiation into macrophages.	Fluocinolone Acetonide	0-6	peroxisome proliferator activated receptor gamma	Homo sapiens	37-46	
31926616-7	2020	Attenuated NO2-FA effects on PPARgamma signaling were observed once cells were differentiated into macrophages, with a significant but lower FABP4 upregulation, and no induction of CD36.	Fluocinolone Acetonide	11-17	peroxisome proliferator activated receptor gamma	Homo sapiens	29-38	
31926616-9	2020	Furthermore, the inhibition of monocyte FA binding by FABP4 diminished NO2-FA-induced upregulation of reporter genes that are transcriptionally regulated by PPARgamma, Keap1/Nrf2 and HSF1, indicating that FABP4 inhibition mitigates NO2-FA signaling actions.	Fluocinolone Acetonide	71-77	peroxisome proliferator activated receptor gamma	Homo sapiens	157-166	
31926616-9	2020	Furthermore, the inhibition of monocyte FA binding by FABP4 diminished NO2-FA-induced upregulation of reporter genes that are transcriptionally regulated by PPARgamma, Keap1/Nrf2 and HSF1, indicating that FABP4 inhibition mitigates NO2-FA signaling actions.	Fluocinolone Acetonide	232-238	peroxisome proliferator activated receptor gamma	Homo sapiens	157-166	
31926616-10	2020	Overall, our results affirm that NO2-FA activate PPARgamma in monocytes and upregulate FABP4 expression, thus promoting a positive amplification loop for the downstream signaling actions of this mediator.	Fluocinolone Acetonide	33-39	peroxisome proliferator activated receptor gamma	Homo sapiens	49-58