PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11553589-1 2001 Variable-region-identical mouse immunoglobulin G1 (IgG1), IgG2b, and IgG2a monoclonal antibodies to the capsular polysaccharide of Cryptococcus neoformans prolong the lives of mice infected with this fungus, while IgG3 is either not protective or enhances infection. Polysaccharides 113-127 immunoglobulin heavy variable V1-9 Mus musculus 69-74 28165193-2 2017 In vivo, both polysaccharides reduced the levels of OVA-specific IgE, IgE-dependent basophil degranulation and IgG2a antibodies, but had no effect on the levels of OVA-specific IgA or IgG1. Polysaccharides 14-29 immunoglobulin heavy variable V1-9 Mus musculus 111-116 9820529-2 1998 Even when converted to T-dependent forms through conjugation to foreign proteins, polysaccharides induce responses that are deficient in many respects, such as induction of murine IgG2a Ab, the isotype that mediates optimal complement fixation and opsonization. Polysaccharides 82-97 immunoglobulin heavy variable V1-9 Mus musculus 180-185 3919387-2 1985 This system, which is based on the autoimmune NZB mouse strain, has been used to produce a monoclonal IgG2a antibody against the meningococcus group B and Escherichia coli K1 polysaccharides, identical homopolymers of alpha (2----8)-linked units of N-acetylneuraminic acid that are extremely poor immunogens. Polysaccharides 175-190 immunoglobulin heavy variable V1-9 Mus musculus 102-107 6811862-1 1982 A murine BALB/c IgG2a (lambda 3) myeloma immunoglobulin SAPC-15 with binding activity for negatively charged polysaccharides has been purified by affinity chromatography, and its interaction with heparin and various other polyanionic antigens has been studied. Polysaccharides 109-124 immunoglobulin heavy variable V1-9 Mus musculus 16-21