PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9614650-1 1998 Apolipoprotein B (apoB) mRNA editing involves a cytidine-to-uridine transition at a select site catalyzed by a cytidine deaminase known as APOBEC-1. Uridine 60-67 apolipoprotein B Homo sapiens 0-16 10403781-1 1999 APOBEC-1, which mediates the editing of apolipoprotein (apo) B mRNA, is the only known member of the C (cytidine)-->U (uridine) editing enzyme subfamily of the cytidine deaminase supergene family. Uridine 122-129 apolipoprotein B Homo sapiens 40-62 9614650-1 1998 Apolipoprotein B (apoB) mRNA editing involves a cytidine-to-uridine transition at a select site catalyzed by a cytidine deaminase known as APOBEC-1. Uridine 60-67 apolipoprotein B Homo sapiens 18-22 7773570-1 1995 A site-specific cytidine deamination (cytidine to uridine) in nuclear apolipoprotein B messenger RNA creates a translational stop codon that produces apolipoprotein B48. Uridine 50-57 apolipoprotein B Homo sapiens 70-86 9512534-1 1998 Apolipoprotein B (apoB) RNA editing involves a cytidine to uridine transition at nucleotide 6666 (C6666) 5" of an essential cis -acting 11 nucleotide motif known as the mooring sequence. Uridine 59-66 apolipoprotein B Homo sapiens 0-16 9512534-1 1998 Apolipoprotein B (apoB) RNA editing involves a cytidine to uridine transition at nucleotide 6666 (C6666) 5" of an essential cis -acting 11 nucleotide motif known as the mooring sequence. Uridine 59-66 apolipoprotein B Homo sapiens 18-22 8767453-3 1996 In the presence of other proteins of the editing enzyme complex, it will deaminate nucleotide 6666 in apoB mRNA, a cytidine residue, converting it to uridine. Uridine 150-157 apolipoprotein B Homo sapiens 102-106 7773570-1 1995 A site-specific cytidine deamination (cytidine to uridine) in nuclear apolipoprotein B messenger RNA creates a translational stop codon that produces apolipoprotein B48. Uridine 50-57 apolipoprotein B Homo sapiens 150-168 8286418-1 1994 Apolipoprotein B (apoB) mRNA in mammalian intestine undergoes direct conversion of cytidine to uridine at nucleotide 6666, generating a UAA stop codon which defines the carboxyl-terminus of apoB48. Uridine 95-102 apolipoprotein B Homo sapiens 0-16 8286418-1 1994 Apolipoprotein B (apoB) mRNA in mammalian intestine undergoes direct conversion of cytidine to uridine at nucleotide 6666, generating a UAA stop codon which defines the carboxyl-terminus of apoB48. Uridine 95-102 apolipoprotein B Homo sapiens 18-22 8286418-1 1994 Apolipoprotein B (apoB) mRNA in mammalian intestine undergoes direct conversion of cytidine to uridine at nucleotide 6666, generating a UAA stop codon which defines the carboxyl-terminus of apoB48. Uridine 95-102 apolipoprotein B Homo sapiens 190-196 2552326-4 1989 2 for review) include the insertion and deletion of uridine residues in mitochondrial messenger RNAs in kinetoplastid protozoa, the conversion of a cytidine to uridine in mammalian apolipoprotein-B mRNA, and the appearance of two non-templated guanosine residues in a paramyxovirus transcript. Uridine 160-167 apolipoprotein B Homo sapiens 181-197 8216250-1 1993 Apolipoprotein (apo-) B mRNA editing at nucleotide 6666 converts cytidine to uridine, transforming the codon for glutamine-2153 to a termination codon. Uridine 77-84 apolipoprotein B Homo sapiens 0-23 8216250-4 1993 The uridine-6666 resulting from the editing reaction had the same ratio of 3H to 32P as did the cytidine-6666, demonstrating that deamination rather than base exchange or nucleotide replacement is the mechanism for apo-B mRNA editing. Uridine 4-11 apolipoprotein B Homo sapiens 215-220 8241469-1 1993 Editing of the mRNA coding for apolipoprotein B involves a cytidine to uridine transition at nucleotide 6666 and enables translation of two protein variants. Uridine 71-78 apolipoprotein B Homo sapiens 31-47 2030940-0 1991 Site-specific creation of uridine from cytidine in apolipoprotein B mRNA editing. Uridine 26-33 apolipoprotein B Homo sapiens 51-67 2030940-5 1991 We conclude that apo B mRNA editing specifically creates a uridine from a cytidine. Uridine 59-66 apolipoprotein B Homo sapiens 17-22 2254300-2 1990 ApoB-48 is generated by a novel RNA editing mechanism which post-transcriptionally modifies apoB mRNA in the intestine by converting cytidine at nucleotide 6666 to uridine. Uridine 164-171 apolipoprotein B Homo sapiens 0-7 2606364-1 1989 Human apolipoprotein (apo)-B mRNA undergoes a novel tissue specific editing reaction which replaces a genomically templated cytidine with uridine. Uridine 138-145 apolipoprotein B Homo sapiens 6-28 23431045-7 2013 Furthermore, APOBEC1 from a variety of mammalian species, which mediates the cytidine (C) to uridine (U) deamination of apolipoprotein B (apoB) mRNA, a protein involved in lipid transport, also plays a role in controlling mobile elements. Uridine 93-100 apolipoprotein B Homo sapiens 120-136 25722083-3 2015 The apolipoprotein B mRNA editing enzymes, catalytic polypeptide-like (APOBECs) are potent restriction factors that can inhibit retroelements by cytosine-to-uridine editing of retroelement DNA after reverse transcription. Uridine 157-164 apolipoprotein B Homo sapiens 4-20 25585043-1 2014 Cytidine (C) to Uridine (U) RNA editing is a post-trancriptional modification that until recently was known to only affect Apolipoprotein b (Apob) RNA and minimally require 2 components of the C to U editosome, the deaminase APOBEC1 and the RNA-binding protein A1CF. Uridine 16-23 apolipoprotein B Homo sapiens 123-139 25585043-1 2014 Cytidine (C) to Uridine (U) RNA editing is a post-trancriptional modification that until recently was known to only affect Apolipoprotein b (Apob) RNA and minimally require 2 components of the C to U editosome, the deaminase APOBEC1 and the RNA-binding protein A1CF. Uridine 16-23 apolipoprotein B Homo sapiens 141-145 2677202-6 1989 Kinetic analysis of the decay of [3H]uridine-labeled apoB mRNA showed that the half-life of apoB mRNA was 16 h. We conclude from these studies that the apoB gene is constitutively expressed in HepG2 cells and that the mechanism of acute regulation of apoB production by these cells must involve co- or post-translational processes. Uridine 37-44 apolipoprotein B Homo sapiens 53-57 2677202-6 1989 Kinetic analysis of the decay of [3H]uridine-labeled apoB mRNA showed that the half-life of apoB mRNA was 16 h. We conclude from these studies that the apoB gene is constitutively expressed in HepG2 cells and that the mechanism of acute regulation of apoB production by these cells must involve co- or post-translational processes. Uridine 37-44 apolipoprotein B Homo sapiens 92-96 2677202-6 1989 Kinetic analysis of the decay of [3H]uridine-labeled apoB mRNA showed that the half-life of apoB mRNA was 16 h. We conclude from these studies that the apoB gene is constitutively expressed in HepG2 cells and that the mechanism of acute regulation of apoB production by these cells must involve co- or post-translational processes. Uridine 37-44 apolipoprotein B Homo sapiens 92-96 2677202-6 1989 Kinetic analysis of the decay of [3H]uridine-labeled apoB mRNA showed that the half-life of apoB mRNA was 16 h. We conclude from these studies that the apoB gene is constitutively expressed in HepG2 cells and that the mechanism of acute regulation of apoB production by these cells must involve co- or post-translational processes. Uridine 37-44 apolipoprotein B Homo sapiens 92-96 27869537-1 2017 Apolipoprotein B mRNA Editing Catalytic Polypeptide-like 1 or APOBEC1 was discovered in 1993 as the zinc-dependent cytidine deaminase responsible for the production of an in frame stop codon in apoB mRNA through modification of cytidine at nucleotide position 6666 to uridine. Uridine 268-275 apolipoprotein B Homo sapiens 0-16 27869537-1 2017 Apolipoprotein B mRNA Editing Catalytic Polypeptide-like 1 or APOBEC1 was discovered in 1993 as the zinc-dependent cytidine deaminase responsible for the production of an in frame stop codon in apoB mRNA through modification of cytidine at nucleotide position 6666 to uridine. Uridine 268-275 apolipoprotein B Homo sapiens 194-198 23431045-7 2013 Furthermore, APOBEC1 from a variety of mammalian species, which mediates the cytidine (C) to uridine (U) deamination of apolipoprotein B (apoB) mRNA, a protein involved in lipid transport, also plays a role in controlling mobile elements. Uridine 93-100 apolipoprotein B Homo sapiens 138-142 10833526-0 2000 Induction of cytidine to uridine editing on cytoplasmic apolipoprotein B mRNA by overexpressing APOBEC-1. Uridine 25-32 apolipoprotein B Homo sapiens 56-72 11672445-0 2001 Commitment of apolipoprotein B RNA to the splicing pathway regulates cytidine-to-uridine editing-site utilization. Uridine 81-88 apolipoprotein B Homo sapiens 14-30 11672445-1 2001 A tripartite motif located in the centre of the 7.5 kb exon 26 of apolipoprotein B (apoB) mRNA directs editosome assembly and site-specific cytidine-to-uridine editing at nucleotide 6666. Uridine 152-159 apolipoprotein B Homo sapiens 66-82 11672445-1 2001 A tripartite motif located in the centre of the 7.5 kb exon 26 of apolipoprotein B (apoB) mRNA directs editosome assembly and site-specific cytidine-to-uridine editing at nucleotide 6666. Uridine 152-159 apolipoprotein B Homo sapiens 84-88 11072063-0 2000 RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA. Uridine 25-32 apolipoprotein B Homo sapiens 47-63 22549984-1 2012 Apolipoprotein B (apo B) messenger RNA (mRNA)-editing, catalytic polypeptide (APOBEC) cytidine deaminases (CDAs), which can insert mutations into DNA and/or RNA as a result of their ability to deaminate cytidine (C) to uridine (U), originated from a branch of the zinc-dependent deaminase superfamily at the beginning of vertebrate radiation. Uridine 219-226 apolipoprotein B Homo sapiens 0-16 21258325-1 2011 Apolipoprotein B-editing enzyme, catalytic polypeptide-1 (APOBEC1) is a cytidine deaminase initially identified by its activity in converting a specific cytidine (C) to uridine (U) in apolipoprotein B (apoB) mRNA transcripts in the small intestine. Uridine 169-176 apolipoprotein B Homo sapiens 184-200 21258325-1 2011 Apolipoprotein B-editing enzyme, catalytic polypeptide-1 (APOBEC1) is a cytidine deaminase initially identified by its activity in converting a specific cytidine (C) to uridine (U) in apolipoprotein B (apoB) mRNA transcripts in the small intestine. Uridine 169-176 apolipoprotein B Homo sapiens 202-206 11815617-1 2002 Apolipoprotein B (apoB) mRNA editing involves site-specific deamination of cytidine to form uridine, resulting in the production of an in-frame stop codon. Uridine 92-99 apolipoprotein B Homo sapiens 0-16 11815617-1 2002 Apolipoprotein B (apoB) mRNA editing involves site-specific deamination of cytidine to form uridine, resulting in the production of an in-frame stop codon. Uridine 92-99 apolipoprotein B Homo sapiens 18-22 11426934-0 2001 Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein B mRNA. Uridine 90-97 apolipoprotein B Homo sapiens 109-125 11264987-1 2001 A site-specific post-transcriptional cytidine to uridine deamination reaction is responsible for the production of apolipoprotein B48 in the mammalian small intestine. Uridine 49-56 apolipoprotein B Homo sapiens 115-133