PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12922945-13 2003 The present results suggest that PTU decreases the progesterone release by granulosa cells via a thyroid-independent mechanism involving the inhibition of post-cAMP pathway, and the activities of intracellular calcium, steroidogenic enzyme, and StAR protein functions. Propylthiouracil 33-36 steroidogenic acute regulatory protein Rattus norvegicus 245-249 12135875-9 2002 In addition to inhibiting hormone secretion, PTU also regulated steroidogenesis by diminishing mRNA expression of StAR. Propylthiouracil 45-48 steroidogenic acute regulatory protein Rattus norvegicus 114-118 12135875-10 2002 These results suggest that PTU acts directly on rat Leydig cells to diminish testosterone production by inhibiting P450(scc) function and StAR expression. Propylthiouracil 27-30 steroidogenic acute regulatory protein Rattus norvegicus 138-142 20924043-0 2010 Stimulatory effects of propylthiouracil on pregnenolone production through upregulation of steroidogenic acute regulatory protein expression in rat granulosa cells. Propylthiouracil 23-39 steroidogenic acute regulatory protein Rattus norvegicus 91-129 20924043-5 2010 Interestingly, the levels of steroidogenic acute regulatory protein (StAR) in both total cell lysate and the mitochondrial fraction were significantly increased by PTU treatment. Propylthiouracil 164-167 steroidogenic acute regulatory protein Rattus norvegicus 29-67 20924043-5 2010 Interestingly, the levels of steroidogenic acute regulatory protein (StAR) in both total cell lysate and the mitochondrial fraction were significantly increased by PTU treatment. Propylthiouracil 164-167 steroidogenic acute regulatory protein Rattus norvegicus 69-73