PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7887985-2 1995 6-Propylthiouracil (PTU), a widely used antithyroid drug for the treatment of Graves" disease, is also a potent inhibitor of Type I iodothyronine deiodinase (ID-1). Propylthiouracil 0-18 inhibitor of DNA binding 1, HLH protein Rattus norvegicus 158-162 7887985-2 1995 6-Propylthiouracil (PTU), a widely used antithyroid drug for the treatment of Graves" disease, is also a potent inhibitor of Type I iodothyronine deiodinase (ID-1). Propylthiouracil 20-23 inhibitor of DNA binding 1, HLH protein Rattus norvegicus 158-162 7887985-3 1995 Inhibition of ID-1 was attributed initially to the formation of a mixed disulfide between PTU and a putative cysteine residue at the active site. Propylthiouracil 90-93 inhibitor of DNA binding 1, HLH protein Rattus norvegicus 14-18 7887985-5 1995 It seemed possible, therefore, that the selenium analog of PTU (PSeU) might be a more potent inhibitor of ID-1 than PTU. Propylthiouracil 59-62 inhibitor of DNA binding 1, HLH protein Rattus norvegicus 106-110 7524506-13 1994 As an inhibitor of ID-1, MSeI is much less than 1% as potent as PTU. Propylthiouracil 64-67 inhibitor of DNA binding 1, HLH protein Rattus norvegicus 19-23