PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16571093-0 2006 Serum thyrotropin receptor antibodies concentrations in patients with Graves" disease before, at the end of methimazole treatment, and after drug withdrawal: evidence that the activity of thyrotropin receptor antibody and/or thyroid response modify during the observation period. Methimazole 108-119 thyroid stimulating hormone receptor Homo sapiens 6-26 18964302-3 2009 Using a bioassay involving Chinese hamster ovary cells transfected with the human thyrotropin receptor, we found that the stimulatory capacity of TRAbs was reduced markedly, by 66+/-22%, upon treatment with rituximab and methimazole for 21 days (p<0.0001), compared to an increase by 33% on average (NS) in patients receiving methimazole alone (p=0.04 between groups). Methimazole 221-232 thyroid stimulating hormone receptor Homo sapiens 82-102 18964302-3 2009 Using a bioassay involving Chinese hamster ovary cells transfected with the human thyrotropin receptor, we found that the stimulatory capacity of TRAbs was reduced markedly, by 66+/-22%, upon treatment with rituximab and methimazole for 21 days (p<0.0001), compared to an increase by 33% on average (NS) in patients receiving methimazole alone (p=0.04 between groups). Methimazole 329-340 thyroid stimulating hormone receptor Homo sapiens 82-102 16571093-0 2006 Serum thyrotropin receptor antibodies concentrations in patients with Graves" disease before, at the end of methimazole treatment, and after drug withdrawal: evidence that the activity of thyrotropin receptor antibody and/or thyroid response modify during the observation period. Methimazole 108-119 thyroid stimulating hormone receptor Homo sapiens 188-208 9309534-8 1997 The last patient developed TSH-receptor antibodies and Graves" disease, requiring methimazole therapy. Methimazole 82-93 thyroid stimulating hormone receptor Homo sapiens 27-39 9222097-6 1997 In addition, serum anti-TSH receptor antibody levels were directly correlated with the absolute numbers of T cells bound to IL-2 (r = 0.565, P < 0.05) and to IL-6 (r = 0.653), P = 0.02) in the hyperthyroid untreated patients, but not in long-term remission euthyroid GD patients or in patients treated with methimazole. Methimazole 310-321 thyroid stimulating hormone receptor Homo sapiens 24-36 8784084-0 1996 Effect of methimazole with or without exogenous L-thyroxine on serum concentrations of thyrotropin (TSH) receptor antibodies in patients with Graves" disease. Methimazole 10-21 thyroid stimulating hormone receptor Homo sapiens 100-113 7551709-1 1995 Regulation of anti-TSH receptor antibody (anti-TSH-R antibody) in Graves" patients (n = 11) by anti-idiotypic antibody was studied using patients sera before and after one year of Methimazole treatment. Methimazole 180-191 thyroid stimulating hormone receptor Homo sapiens 19-31 7551709-1 1995 Regulation of anti-TSH receptor antibody (anti-TSH-R antibody) in Graves" patients (n = 11) by anti-idiotypic antibody was studied using patients sera before and after one year of Methimazole treatment. Methimazole 180-191 thyroid stimulating hormone receptor Homo sapiens 47-52 2946953-9 1987 Methimazole treatment was accompanied by a gradual reduction in circulating levels of thyrotropin-receptor, microsomal, and thyroglobulin autoantibodies. Methimazole 0-11 thyroid stimulating hormone receptor Homo sapiens 86-106 34544941-1 2022 A 28-year-old Japanese woman positive for TSH receptor antibody and anti-nuclear antibody complained of difficulty seeing nearby objects, severe throbbing retro-orbital pain, diplopia, blepharoptosis and upward gaze palsy when she became hypothyroid during treatment with 30 mg methylmercaptoimidazole for Graves" hyperthyroidism. Methimazole 278-301 thyroid stimulating hormone receptor Homo sapiens 42-54 35228417-0 2022 A Case of Graves" Disease with Thymic Hyperplasia: The Response of the Thyroid Function, Thyrotropin Receptor Autoantibody, and Thymic Size to Thiamazole Treatment. Methimazole 143-153 thyroid stimulating hormone receptor Homo sapiens 89-109 35228417-4 2022 The thyroid function and thyroid-stimulating hormone receptor antibody (TRAb) were normalized one and five months after thiamazole initiation, respectively. Methimazole 120-130 thyroid stimulating hormone receptor Homo sapiens 25-61 2896115-3 1987 After 12 months methimazole therapy 25 patients had TSH-receptor antibodies (66%) within the normal range. Methimazole 16-27 thyroid stimulating hormone receptor Homo sapiens 52-64 2869050-0 1986 Methimazole, but not betamethasone, prevents 131I treatment-induced rises in thyrotropin receptor autoantibodies in hyperthyroid Graves" disease. Methimazole 0-11 thyroid stimulating hormone receptor Homo sapiens 77-97 30753531-14 2019 Subsequent to 12-month methimazole treatment, samples from euthyroid GD + GO patients were still TSH-R-Ab positive at the high dilution of 1:243. Methimazole 23-34 thyroid stimulating hormone receptor Homo sapiens 97-102 34027861-0 2021 The Relationship between Third-generation TSH Receptor Antibody Positivity and Cumulative Methimazole Dose Used until Remission in Graves" Disease. Methimazole 90-101 thyroid stimulating hormone receptor Homo sapiens 42-54 34027861-1 2021 OBJECTIVE: To determine the relationship between the positivity of third-generation TSH receptor antibody (TRAb) at the time of diagnosis and the cumulative methimazole dose used until remission in patients with Graves" disease. Methimazole 157-168 thyroid stimulating hormone receptor Homo sapiens 84-96 30705666-11 2018 A blood sample showed overt hyperthyroidism and the persistence of anti-TSH receptor antibodies (TRAb) during treatment with methimazole. Methimazole 125-136 thyroid stimulating hormone receptor Homo sapiens 72-84 28162094-8 2017 CONCLUSIONS: The possible explanations for serial changes in the thyroid-stimulating hormone-binding inhibitory immunoglobulin results in our patient include the presence of thyroid-stimulating hormone receptor antibody, which is bioactive but less reactive on thyroid-stimulating hormone-binding inhibitory immunoglobulin assays, or the effect of reduced levels of circulating thyroid-stimulating hormone receptor antibody upon improvement of thyroid autoimmunity with thiamazole treatment. Methimazole 470-480 thyroid stimulating hormone receptor Homo sapiens 174-210 27927064-2 2017 Former studies have shown Yingliu mixture combined with methimazole (Y-M) can effectively improve thyroid function and decrease thyrotropin-receptor antibody level. Methimazole 56-67 thyroid stimulating hormone receptor Homo sapiens 128-148