PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28653416-10 2017 Recently, the structure of the complex of LPO with a potent antithyroid drug, 1-methylimidazole-2-thiol (methimazole, MMZ) was also determined. Methimazole 78-103 lactoperoxidase Homo sapiens 42-45 28653416-10 2017 Recently, the structure of the complex of LPO with a potent antithyroid drug, 1-methylimidazole-2-thiol (methimazole, MMZ) was also determined. Methimazole 105-116 lactoperoxidase Homo sapiens 42-45 28653416-10 2017 Recently, the structure of the complex of LPO with a potent antithyroid drug, 1-methylimidazole-2-thiol (methimazole, MMZ) was also determined. Methimazole 118-121 lactoperoxidase Homo sapiens 42-45 28653416-11 2017 It showed that MMZ bound to LPO in the substrate-binding site on the distal heme side with 2 orientations. Methimazole 15-18 lactoperoxidase Homo sapiens 28-31 27398304-0 2016 Dual binding mode of antithyroid drug methimazole to mammalian heme peroxidases - structural determination of the lactoperoxidase-methimazole complex at 1.97 A resolution. Methimazole 38-49 lactoperoxidase Homo sapiens 114-129 27398304-0 2016 Dual binding mode of antithyroid drug methimazole to mammalian heme peroxidases - structural determination of the lactoperoxidase-methimazole complex at 1.97 A resolution. Methimazole 130-141 lactoperoxidase Homo sapiens 114-129 27398304-4 2016 In order to determine the mode of binding of antithyroid drugs to thyroid peroxidase, we have determined the crystal structure of LPO complexed with an antithyroid drug, methimazole (MMZ) at 1.97 A resolution. Methimazole 170-181 lactoperoxidase Homo sapiens 130-133 27398304-4 2016 In order to determine the mode of binding of antithyroid drugs to thyroid peroxidase, we have determined the crystal structure of LPO complexed with an antithyroid drug, methimazole (MMZ) at 1.97 A resolution. Methimazole 183-186 lactoperoxidase Homo sapiens 130-133 16855736-1 2006 The inhibition of lactoperoxidase (LPO)-catalyzed iodination of l-tyrosine by the anti-thyroid drug methimazole (MMI) and its selenium analogue (MSeI) is described. Methimazole 100-111 lactoperoxidase Homo sapiens 18-33 16855736-1 2006 The inhibition of lactoperoxidase (LPO)-catalyzed iodination of l-tyrosine by the anti-thyroid drug methimazole (MMI) and its selenium analogue (MSeI) is described. Methimazole 100-111 lactoperoxidase Homo sapiens 35-38