PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20837888-6 2010 Endothelial-specific overexpression of CYP4A2 resulted in increased expression of vascular angiotensin-converting enzyme (ACE) and angiotensin II type 1 receptor and increased levels of plasma and tissue angiotensin II; all were attenuated by treatment with HET0016, an inhibitor of 20-HETE synthesis, or with 20-hydroxyeicosa-6(Z), 15(Z)-dienoic acid. Hydroxyeicosatetraenoic Acids 286-290 cytochrome P450, family 4, subfamily a, polypeptide 2 Rattus norvegicus 39-45 16543501-4 2006 Relative to data in control rats, arteries from Adv-CYP4A2-transduced rats produced more 20-HETE (129+/-10 versus 97+/-7 pmol/mg protein, P<0.01) and less nitric oxide (NO; 4.2+/-1.6 versus 8.4+/-1 nmol nitrite+nitrate/mg; P<0.05). Hydroxyeicosatetraenoic Acids 91-96 cytochrome P450, family 4, subfamily a, polypeptide 2 Rattus norvegicus 52-58