PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17640979-8 2007 We found that HETEs enhanced IL-1-induced COX-2 mRNA levels in CMF as the result of increased p38, MK-2, and HuR activity, increasing message stability greater than that observed with IL-1 alone. Hydroxyeicosatetraenoic Acids 14-19 interleukin 1 alpha Homo sapiens 29-33 8557627-3 1996 While exploring effects of IL-1 on islet arachidonic acid metabolism, we found that IL-1 increases islet production of the 12-lipoxygenase product 12-hydroxyeicosatetraenoic acid 12-(HETE). Hydroxyeicosatetraenoic Acids 183-187 interleukin 1 alpha Homo sapiens 84-88 8395696-5 1993 In the G292 cells, IL-1 alpha (50 U/ml) induced a 10-fold increase in PGE2 production at all the incubation times tested, and a significant two-fold increase in 5 hydroxyeicosatetraenoic acid (HETE) formation after 48 h. These effects were not seen in SaOS-2 cells under identical conditions. Hydroxyeicosatetraenoic Acids 163-191 interleukin 1 alpha Homo sapiens 19-29 8395696-5 1993 In the G292 cells, IL-1 alpha (50 U/ml) induced a 10-fold increase in PGE2 production at all the incubation times tested, and a significant two-fold increase in 5 hydroxyeicosatetraenoic acid (HETE) formation after 48 h. These effects were not seen in SaOS-2 cells under identical conditions. Hydroxyeicosatetraenoic Acids 193-197 interleukin 1 alpha Homo sapiens 19-29 17640979-8 2007 We found that HETEs enhanced IL-1-induced COX-2 mRNA levels in CMF as the result of increased p38, MK-2, and HuR activity, increasing message stability greater than that observed with IL-1 alone. Hydroxyeicosatetraenoic Acids 14-19 interleukin 1 alpha Homo sapiens 184-188