PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11483407-11	2001	NF-kappaB DNA-protein binding and ICAM-1 promoter activity were enhanced by TNF-alpha and these effects were inhibited by D 609, calphostin C, or tyrphostin 23, but not by PD 98059 or SB 203580.	Antimony	184-186	tumor necrosis factor	Homo sapiens	76-85	
22002864-3	2012	In this study, we found that inhibition of p38 MAPK with SB-203580 (SB) reduced H(2)O(2)-stimulated secretion of TNF-alpha, whereas pre-activation of p38 MAPK with sodium arsenite (SA) enhanced H(2)O(2)-stimulated secretion of TNF-alpha.	Antimony	57-59	tumor necrosis factor	Homo sapiens	113-122	
22002864-4	2012	In addition, pretreatment of cells with TNF-alpha increased basal and H(2)O(2)-stimulated p38 MAPK and apoptosis of cardiac myocytes, and p38 MAPK-associated apoptosis of cardiac myocytes induced by TNF-alpha was blocked by inhibition of p38 MAPK with SB.	Antimony	252-254	tumor necrosis factor	Homo sapiens	40-49	
18603920-9	2006	Recently, another substance known as Cytokines e.g. IL-6, Tumour necrosis factor (TNF), have also been labelled to be responsible for depressed excretory function of liver and may lead to increase in SB level without rise in liver enzymes.	Antimony	200-202	tumor necrosis factor	Homo sapiens	58-80	
18603920-9	2006	Recently, another substance known as Cytokines e.g. IL-6, Tumour necrosis factor (TNF), have also been labelled to be responsible for depressed excretory function of liver and may lead to increase in SB level without rise in liver enzymes.	Antimony	200-202	tumor necrosis factor	Homo sapiens	82-85	
15138590-11	2004	Treatment of MCF-7TN-R cells with SB partially restored sensitivity to TNF-induced cell death.	Antimony	34-36	tumor necrosis factor	Homo sapiens	71-74	
12637577-2	2003	Here we show unequivocally that the production of interleukin (IL)-1beta, IL-6, IL-10, and tumor necrosis factor alpha (TNFalpha) requires p38 MAPK activity by demonstrating that the inhibitory effects of SB 203580 were reversed by expression of an SB 203580-resistant form of p38alpha (SBR-p38alpha) that fails to bind to SB 203580.	Antimony	205-207	tumor necrosis factor	Homo sapiens	91-118	
12637577-2	2003	Here we show unequivocally that the production of interleukin (IL)-1beta, IL-6, IL-10, and tumor necrosis factor alpha (TNFalpha) requires p38 MAPK activity by demonstrating that the inhibitory effects of SB 203580 were reversed by expression of an SB 203580-resistant form of p38alpha (SBR-p38alpha) that fails to bind to SB 203580.	Antimony	205-207	tumor necrosis factor	Homo sapiens	120-128	
12637577-2	2003	Here we show unequivocally that the production of interleukin (IL)-1beta, IL-6, IL-10, and tumor necrosis factor alpha (TNFalpha) requires p38 MAPK activity by demonstrating that the inhibitory effects of SB 203580 were reversed by expression of an SB 203580-resistant form of p38alpha (SBR-p38alpha) that fails to bind to SB 203580.	Antimony	249-251	tumor necrosis factor	Homo sapiens	120-128	
9772703-5	1996	SB(12.5-100 micrograms.ml-1) was also shown to markedly reduce TNF cytotoxicity on human hepatic cell line GSG-7701 and mouse fibroblastic cell line L929 cells concentration-dependently.	Antimony	0-2	tumor necrosis factor	Homo sapiens	63-66