PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12763029-5 2003 Pretreatment with the p38 MAPK inhibitors SB203580 (10 microM) (SB) or SKF-86002 (10 microM) (SKF) potently inhibited AngII-induced p38 MAPK activation, but enhanced AngII-mediated ERK1/2 activation. Antimony 42-44 mitogen-activated protein kinase 3 Homo sapiens 26-30 12763029-5 2003 Pretreatment with the p38 MAPK inhibitors SB203580 (10 microM) (SB) or SKF-86002 (10 microM) (SKF) potently inhibited AngII-induced p38 MAPK activation, but enhanced AngII-mediated ERK1/2 activation. Antimony 42-44 mitogen-activated protein kinase 3 Homo sapiens 136-140 12763029-5 2003 Pretreatment with the p38 MAPK inhibitors SB203580 (10 microM) (SB) or SKF-86002 (10 microM) (SKF) potently inhibited AngII-induced p38 MAPK activation, but enhanced AngII-mediated ERK1/2 activation. Antimony 42-44 mitogen-activated protein kinase 3 Homo sapiens 181-187 12876384-12 2003 Interestingly, the SB compound also significantly inhibited FAK phosphorylation at Y397 (23 +/- 3% in adherent, 30 +/- 4% in non-adherent cells at 30 minutes and 35 +/- 4% in adherent, 46 +/- 14% in non-adherent cells after 6 hours, p<0.05 for each) and greatly enhanced phosphorylation of ERK1/2, a putative anti-apoptotic component of the MAPK cascade. Antimony 19-21 mitogen-activated protein kinase 3 Homo sapiens 293-299 12876384-12 2003 Interestingly, the SB compound also significantly inhibited FAK phosphorylation at Y397 (23 +/- 3% in adherent, 30 +/- 4% in non-adherent cells at 30 minutes and 35 +/- 4% in adherent, 46 +/- 14% in non-adherent cells after 6 hours, p<0.05 for each) and greatly enhanced phosphorylation of ERK1/2, a putative anti-apoptotic component of the MAPK cascade. Antimony 19-21 mitogen-activated protein kinase 3 Homo sapiens 344-348 11676560-9 2001 Based on the ability of SB and PD to respectively block LPS-inducible tyrosine phosphorylation of p38 MAPK and Erk1/2, it was evident that tyrosine phosphorylation of MAPKs is required for mediating LPS-inducible mTF synthesis and upregulation. Antimony 24-26 mitogen-activated protein kinase 3 Homo sapiens 111-117