PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31408586-10	2019	Moreover, lycopene promotes IL-4-induced M2 polarization by increasing the phosphorylation levels of STAT6 and Akt in Raw 264.7 macrophages.	Lycopene	10-18	thymoma viral proto-oncogene 1	Mus musculus	111-114	
31006097-7	2019	Furthermore, lycopene reduced the ratios of Bax:Bcl-2 and cleaved caspase-3:caspase-3 and the level of cytochrome C, increased the levels of synaptophysin (SYP) and postsynaptic density 95 (PSD95) and activated the PI3K/Akt pathway.	Lycopene	13-21	thymoma viral proto-oncogene 1	Mus musculus	220-223	
31006097-8	2019	In conclusion, lycopene attenuated oxidative stress and reduced t-BHP-induced cell apoptosis, and the mechanism is likely related to activation of the PI3K/Akt pathway.	Lycopene	15-23	thymoma viral proto-oncogene 1	Mus musculus	156-159	
24943973-10	2014	Further investigation revealed that lycopene could activate phosphoinositide-3 kinase (PI3K)/Akt.	Lycopene	36-44	thymoma viral proto-oncogene 1	Mus musculus	93-96	
24943973-11	2014	Pretreatment with PI3K/Akt inhibitors prevented the protective effect of lycopene on MSCs.	Lycopene	73-81	thymoma viral proto-oncogene 1	Mus musculus	23-26	
32253029-0	2020	Effects of lycopene on vascular remodeling through the LXR-PI3K-AKT signaling pathway in APP/PS1 mice.	Lycopene	11-19	thymoma viral proto-oncogene 1	Mus musculus	64-67	
31006097-0	2019	Lycopene protects against t-BHP-induced neuronal oxidative damage and apoptosis via activation of the PI3K/Akt pathway.	Lycopene	0-8	thymoma viral proto-oncogene 1	Mus musculus	107-110	
30948928-11	2019	Upon IFNgamma stimulation, lycopene diminished PD-L1 expression via activating JAK and repressing phosphorylation of AKT.	Lycopene	27-35	thymoma viral proto-oncogene 1	Mus musculus	117-120