PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28386381-8	2017	RESULTS: In cells treated with lycopene and LPS, the mRNA expression of TNF-alpha, IL-1beta, IL-6, iNOS, and COX-2 were decreased significantly in a dose-dependent manner (P < 0.05).	Lycopene	31-39	interleukin 1 beta	Homo sapiens	83-91	
28386381-11	2017	CONCLUSIONS: Lycopene restrains NF-kappaB and JNK activation, which causes inflammation, and suppresses the expression of TNF-alpha, IL-1beta, IL-6, COX-2, and iNOS in SW480 human colorectal cancer cells.	Lycopene	13-21	interleukin 1 beta	Homo sapiens	133-141	
18389438-6	2008	Lycopene induced a dose-dependent increase in IL1beta, and TNFalpha production and a decrease in IL-2, IL-10 and IFNgamma secretion, whereas that of IL-6 and IL-1ra was not affected.	Lycopene	0-8	interleukin 1 beta	Homo sapiens	46-53	
27609268-10	2016	Furthermore, lycopene decreased LPS-induced expression of IL-1beta and HO-1 in the hippocampus together with decreasing level of IL-6 and TNF-alpha in the plasma.	Lycopene	13-21	interleukin 1 beta	Homo sapiens	58-66	
22152988-3	2012	The objective of the present study was to investigate whether lycopene and beta-carotene in micelles (M), at concentrations that could be reached via the diet (10-25 mug/ml) could aid in the reduction of TNF-alpha plus IL-1beta-induced inflammation of Caco-2 human epithelial cells.	Lycopene	62-70	interleukin 1 beta	Homo sapiens	219-227	
10856518-11	2000	While other carotenoids were ineffective, lycopene attenuated both IL-1beta-stimulated and spontaneous HAEC adhesion to U937 monocytic cells by 20 and 25%, respectively.	Lycopene	42-50	interleukin 1 beta	Homo sapiens	67-75