PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27928873-0	2017	Lycopene inhibits regulator of calcineurin 1-mediated apoptosis by reducing oxidative stress and down-regulating Nucling in neuronal cells.	Lycopene	0-8	regulator of calcineurin 1	Homo sapiens	18-44	
27928873-4	2017	The present study is to investigate whether lycopene inhibits apoptosis by reducing ROS levels, NF-kappaB activation, expression of the apoptosis regulator Nucling, cell viability, and indices of apoptosis (cytochrome c release, caspase-3 activation) in RCAN1-overexpressing neuronal cells.	Lycopene	44-52	regulator of calcineurin 1	Homo sapiens	254-259	
27928873-6	2017	Lycopene decreased intracellular and mitochondrial ROS levels, NF-kappaB activity, and Nucling expression while it reversed decrease in mitochondrial membrane potential, mitochondrial respiration, and glycolytic function in RCAN1-overexpressing cells.	Lycopene	0-8	regulator of calcineurin 1	Homo sapiens	224-229	
27928873-7	2017	Lycopene inhibited cell death, DNA fragmentation, caspase-3 activation, and cytochrome c release in RCAN1-overexpressing cells.	Lycopene	0-8	regulator of calcineurin 1	Homo sapiens	100-105	
27928873-8	2017	CONCLUSION: Lycopene inhibits RCAN1-mediated apoptosis by reducing ROS levels and by inhibiting NF-kappaB activation, Nucling induction, and the increase in apoptotic indices in neuronal cells.	Lycopene	12-20	regulator of calcineurin 1	Homo sapiens	30-35