PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24971153-5 2014 Moreover, lycopene treatment prevented the increase in the phosphorylation of serine-threonine kinase Akt and glycogen synthase kinase-3beta (GSK-3 beta ) caused by U-II without affecting the protein levels of the phosphatase and tensin homolog deleted on chromosome 10 (PTEN). Lycopene 10-18 phosphatase and tensin homolog Rattus norvegicus 271-275 24971153-6 2014 However, lycopene increased the PTEN activity level, suggesting that lycopene prevents ROS-induced PTEN inactivation. Lycopene 9-17 phosphatase and tensin homolog Rattus norvegicus 32-36 24971153-6 2014 However, lycopene increased the PTEN activity level, suggesting that lycopene prevents ROS-induced PTEN inactivation. Lycopene 69-77 phosphatase and tensin homolog Rattus norvegicus 32-36 24971153-6 2014 However, lycopene increased the PTEN activity level, suggesting that lycopene prevents ROS-induced PTEN inactivation. Lycopene 69-77 phosphatase and tensin homolog Rattus norvegicus 99-103 24971153-7 2014 These findings imply that lycopene yields antihypertrophic effects that can prevent the activation of the Akt/GSK-3 beta hypertrophic pathway by modulating PTEN inactivation through U-II treatment. Lycopene 26-34 phosphatase and tensin homolog Rattus norvegicus 156-160