PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21232531-1	2011	Retinol dehydrogenase 12 (RDH12) is a microsomal enzyme that catalyzes the reduction of all-trans-retinaldehyde to all-trans-retinol when expressed in cells.	Retinaldehyde	88-111	retinol dehydrogenase 12	Homo sapiens	0-24	
31237438-4	2019	In the retina, RDH12 plays a critical role in reducing toxic retinaldehydes generated by visual cycle activity that is required for the light response of the photoreceptor cells.	Retinaldehyde	61-75	retinol dehydrogenase 12	Homo sapiens	15-20	
21232531-1	2011	Retinol dehydrogenase 12 (RDH12) is a microsomal enzyme that catalyzes the reduction of all-trans-retinaldehyde to all-trans-retinol when expressed in cells.	Retinaldehyde	88-111	retinol dehydrogenase 12	Homo sapiens	26-31	
12226107-7	2002	Furthermore, photoreceptor RDH12 could be involved in the production of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments.	Retinaldehyde	72-86	retinol dehydrogenase 12	Homo sapiens	27-32	
18396173-3	2008	Our previous study suggested that RDH12 protects cells against toxic levels of retinaldehyde and retinoic acid [S.A. Lee, O.V.	Retinaldehyde	79-92	retinol dehydrogenase 12	Homo sapiens	34-39	
18396173-10	2008	At high concentrations, nonanal inhibited the activity of RDH12 towards retinaldehyde, suggesting that nonanal was metabolized by RDH12.	Retinaldehyde	72-85	retinol dehydrogenase 12	Homo sapiens	58-63	
18396173-10	2008	At high concentrations, nonanal inhibited the activity of RDH12 towards retinaldehyde, suggesting that nonanal was metabolized by RDH12.	Retinaldehyde	72-85	retinol dehydrogenase 12	Homo sapiens	130-135	
18396173-12	2008	Thus, the results of this study showed that RDH12 is more effective in protection against retinaldehyde than against medium-chain aldehydes, and that medium-chain aldehydes, especially 4-hydroxynonenal, severely disrupt cellular retinoid homeostasis.	Retinaldehyde	90-103	retinol dehydrogenase 12	Homo sapiens	44-49