PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33495337-6 2021 Finally, we identified a previously unrecognized, OCT3-dependent pathway of doxorubicin-induced cardiotoxicity that results in a downstream signaling cascade involving the calcium-binding proteins S100A8 and S100A9. Calcium 172-179 S100 calcium binding protein A9 Homo sapiens 208-214 2478889-6 1989 All the proteins have an Mr of approximately 10,000 with the exception of p14 which has a longer C-terminal sequence after the second calcium-binding domain. Calcium 134-141 S100 calcium binding protein A9 Homo sapiens 74-77 33174028-1 2020 S100 calcium binding protein A8 (S100A8) and A9 (S100A9) belong to the S100 family of calcium-binding proteins and have important roles in inflammation. Calcium 5-12 S100 calcium binding protein A9 Homo sapiens 49-55 32805279-2 2020 The S100 calcium binding proteins S100A8 and S100A9, and their extracellular complex form, S100A8-A9, are found in high amounts in human breast milk. Calcium 9-16 S100 calcium binding protein A9 Homo sapiens 45-51 33523865-2 2021 Here, we show that the calcium-dependent cytokines S100A8 and S100A9 are recruited to numerous promoters and enhancers in a model of breast cellular transformation. Calcium 23-30 S100 calcium binding protein A9 Homo sapiens 62-68 30586702-13 2019 VEGFR1 inhibition by VEGF165b results in S100A8/S100A9-mediated calcium influx to induce an M1-like phenotype that impairs ischemic muscle revascularization and perfusion recovery. Calcium 64-71 S100 calcium binding protein A9 Homo sapiens 48-54 32879128-1 2020 OBJECTIVES: Lymph node metastasis affects the initial treatment strategy for cervical cancer and is hard to be diagnosed in clinical practice.This paper aims to explore the relationship between calcium-binding A9 (S100A9) and lymph node metastasis (LNM) in cervical cancer, and to determine the predictive value of S100A9 for LNM in cervical cancer. Calcium 194-201 S100 calcium binding protein A9 Homo sapiens 214-220 32879128-1 2020 OBJECTIVES: Lymph node metastasis affects the initial treatment strategy for cervical cancer and is hard to be diagnosed in clinical practice.This paper aims to explore the relationship between calcium-binding A9 (S100A9) and lymph node metastasis (LNM) in cervical cancer, and to determine the predictive value of S100A9 for LNM in cervical cancer. Calcium 194-201 S100 calcium binding protein A9 Homo sapiens 315-321 32202636-7 2020 Our RNA-seq and ChIP-seq analysis indicate that S100a9, the S100 calcium-binding protein, is a target gene of Setd2 and that the addition of recombinant S100a9 weakens the effect of Setd2 deficiency in the NHD13+ HSPCs. Calcium 65-72 S100 calcium binding protein A9 Homo sapiens 48-54 32202636-7 2020 Our RNA-seq and ChIP-seq analysis indicate that S100a9, the S100 calcium-binding protein, is a target gene of Setd2 and that the addition of recombinant S100a9 weakens the effect of Setd2 deficiency in the NHD13+ HSPCs. Calcium 65-72 S100 calcium binding protein A9 Homo sapiens 153-159 32503348-5 2020 By combining the unbiased PTX with mRNA expression analysis and literature-based predictions of pro-malignant functions, we nominated the two calcium-binding proteins S100A8 (MRP8) and S100A9 (MRP14) as well as galactin-3-binding protein LGALS3BP (MAC-2-BP) as putative determinants of pancreatic TICs. Calcium 142-149 S100 calcium binding protein A9 Homo sapiens 185-191 32503348-5 2020 By combining the unbiased PTX with mRNA expression analysis and literature-based predictions of pro-malignant functions, we nominated the two calcium-binding proteins S100A8 (MRP8) and S100A9 (MRP14) as well as galactin-3-binding protein LGALS3BP (MAC-2-BP) as putative determinants of pancreatic TICs. Calcium 142-149 S100 calcium binding protein A9 Homo sapiens 193-198 31055998-1 2019 OBJECTIVE: S100A9 is a calcium- and zinc-binding molecule of S100 family. Calcium 23-30 S100 calcium binding protein A9 Homo sapiens 11-17 30266587-1 2018 S100A8/A9, a heterodimer complex composed of calcium-binding proteins S100A8 and S100A9, is significantly increased in the serum of multiple sclerosis (MS) patients. Calcium 45-52 S100 calcium binding protein A9 Homo sapiens 81-87 29568473-11 2017 As an example for the latter case, the pro-inflammatory calcium binding protein S100A9 is shown not to incorporate into the beta-sheets of Abeta42. Calcium 56-63 S100 calcium binding protein A9 Homo sapiens 80-86 29933628-10 2018 The results suggest that the calcium-binding proteins S100A8 and S100A9 in myeloid cells have an immune regulatory effect. Calcium 29-36 S100 calcium binding protein A9 Homo sapiens 65-71 29733516-1 2018 BACKGROUND: The purpose of this study was to evaluate the correlation between calcium-binding protein S100A8 and S100A9 expression in non-small cell lung cancer (NSCLC) and patients" clinical features. Calcium 78-85 S100 calcium binding protein A9 Homo sapiens 113-119 29933628-0 2018 Calcium-Binding Proteins S100A8 and S100A9: Investigation of Their Immune Regulatory Effect in Myeloid Cells. Calcium 0-7 S100 calcium binding protein A9 Homo sapiens 36-42 29933628-1 2018 High expression levels of the calcium-binding proteins S100A8 and S100A9 in myeloid cells in kidney transplant rejections are associated with a favorable outcome. Calcium 30-37 S100 calcium binding protein A9 Homo sapiens 66-72 29301628-6 2018 RESULTS: Platelet RNA sequence profiling mapped a robust up-regulation of myeloid-related protein (MRP)-14 mRNA, a potent calcium binding protein heterodimer, in PAD. Calcium 122-129 S100 calcium binding protein A9 Homo sapiens 74-106 28550118-6 2017 Moreover, upstream and downstream signaling events activated by MSUs in human neutrophils were also potentiated by S100A9, including the mobilization of intracellular calcium stores, tyrosine phosphorylation, the serine phosphorylation of PKC substrates, Akt, and p38. Calcium 167-174 S100 calcium binding protein A9 Homo sapiens 115-121 28276321-5 2017 Among the differential proteins identified, calcium-binding protein S100A9 was overexpressed in HPC tissues compared with normal adjacent tissues, and S100A9 expression in metastatic tissues and advanced tumor tissues was higher than in nonmetastatic tissues and early tumor tissues. Calcium 44-51 S100 calcium binding protein A9 Homo sapiens 68-74 28063140-1 2017 S100A9, a calcium-binding protein, participates in the inflammatory process and development of various tumors, thus attracting much attention in the field of cancer biology. Calcium 10-17 S100 calcium binding protein A9 Homo sapiens 0-6 29296934-5 2016 This antibody, termed G213, reacted with clusters of neutrophils located in the central area of granulomas, and a biochemical analysis identified the G213-reactive antigen as S100A9, a calcium-binding protein of the S100 family, which was expressed abundantly in neutrophils. Calcium 185-192 S100 calcium binding protein A9 Homo sapiens 175-181 27382389-1 2016 PURPOSE: The S100 gene family, which comprises over 20 members, including S100A1, S100A2, S100A8, S100A9, profilaggrin, and hornerin encodes low molecular weight calcium-binding proteins with physiological and pathological roles in keratinization. Calcium 162-169 S100 calcium binding protein A9 Homo sapiens 98-104 26892330-5 2016 Amyloidal plaques were enriched in the deamidated variant of protein S100A9, and structural analysis indicated that both the low- and high-affinity calcium binding motifs of S100A9 were deamidated exclusively in the aggregated fraction, suggesting altered charge state and function of this protein in brain tissues affected by dementia. Calcium 148-155 S100 calcium binding protein A9 Homo sapiens 69-75 26933915-1 2016 Calgranulin B is a small, calcium-binding protein expressed in neutrophils that is secreted into the tumor microenvironment in cancer cases. Calcium 26-33 S100 calcium binding protein A9 Homo sapiens 0-13 26892330-5 2016 Amyloidal plaques were enriched in the deamidated variant of protein S100A9, and structural analysis indicated that both the low- and high-affinity calcium binding motifs of S100A9 were deamidated exclusively in the aggregated fraction, suggesting altered charge state and function of this protein in brain tissues affected by dementia. Calcium 148-155 S100 calcium binding protein A9 Homo sapiens 174-180 26892330-7 2016 CONCLUSION: UC-coupled proteomics revealed that brain amyloidal plaques are enriched in deamidated proteins, and suggested that altered charge state and calcium-binding capacity of S100A9 may enhance protein aggregation and promote neurodegeneration in the human brain. Calcium 153-160 S100 calcium binding protein A9 Homo sapiens 181-187 26508452-2 2015 Two calcium-binding proteins S100A8 and S100A9 act as important mediators in acute and chronic inflammation. Calcium 4-11 S100 calcium binding protein A9 Homo sapiens 40-46 24691441-1 2014 Expression of the gene encoding the S100 calcium-modulated protein family member MRP-14 (also known as S100A9) is elevated in platelets from patients presenting with acute myocardial infarction (MI) compared with those from patients with stable coronary artery disease; however, a causal role for MRP-14 in acute coronary syndromes has not been established. Calcium 41-48 S100 calcium binding protein A9 Homo sapiens 81-87 26038301-1 2015 S100A8, S100A9, and calprotectin (the S100A8/S100A9 complex) are calcium-binding proteins that promote extracellular pro-inflammatory functions and may play an important role in periodontal disease. Calcium 65-72 S100 calcium binding protein A9 Homo sapiens 8-14 26038301-1 2015 S100A8, S100A9, and calprotectin (the S100A8/S100A9 complex) are calcium-binding proteins that promote extracellular pro-inflammatory functions and may play an important role in periodontal disease. Calcium 65-72 S100 calcium binding protein A9 Homo sapiens 45-51 26315114-1 2015 S100A9 is a calcium-binding protein with two EF-hands and frequently deregulated in several cancer types, however, with no clear role in oral cancer. Calcium 12-19 S100 calcium binding protein A9 Homo sapiens 0-6 25907296-1 2015 S100A9 belongs to the S100 family of calcium-binding proteins and is over-expressed in many human tumors including hepatocellular carcinoma (HCC). Calcium 37-44 S100 calcium binding protein A9 Homo sapiens 0-6 25535818-3 2015 Calprotectin (MRP8/MRP14) is a complex of calcium- and zinc-binding proteins that belong to the S100 protein family. Calcium 42-49 S100 calcium binding protein A9 Homo sapiens 19-24 26448179-3 2015 S100A9 is a calcium-binding protein that is associated with inflammation and expressed not only in myeloid cells but also in some tumours. Calcium 12-19 S100 calcium binding protein A9 Homo sapiens 0-6 25488653-2 2015 Our data reveal a rich diversity of proteins that are dynamically modulated, and we selectively highlight a family of calcium binding proteins (S-100 molecules) including calcyclin (S100-A6), calgranulins A (S100-A8) and B (S100-A9), and calgizzarin (S100-A11). Calcium 118-125 S100 calcium binding protein A9 Homo sapiens 224-231 24691441-1 2014 Expression of the gene encoding the S100 calcium-modulated protein family member MRP-14 (also known as S100A9) is elevated in platelets from patients presenting with acute myocardial infarction (MI) compared with those from patients with stable coronary artery disease; however, a causal role for MRP-14 in acute coronary syndromes has not been established. Calcium 41-48 S100 calcium binding protein A9 Homo sapiens 103-109 24691441-1 2014 Expression of the gene encoding the S100 calcium-modulated protein family member MRP-14 (also known as S100A9) is elevated in platelets from patients presenting with acute myocardial infarction (MI) compared with those from patients with stable coronary artery disease; however, a causal role for MRP-14 in acute coronary syndromes has not been established. Calcium 41-48 S100 calcium binding protein A9 Homo sapiens 297-303 23456298-1 2013 S100A8 and S100A9 (S100A8/A9) are low-molecular weight members of the S100 family of calcium-binding proteins. Calcium 85-92 S100 calcium binding protein A9 Homo sapiens 11-17 23563247-1 2013 S100A9 is a calcium-binding protein and subunit of antimicrobial calprotectin complex (S100A8/A9). Calcium 12-19 S100 calcium binding protein A9 Homo sapiens 0-6 23682982-1 2013 S100A9 belongs to the S100 family of calcium-binding proteins and plays a key role in many inflammatory conditions. Calcium 37-44 S100 calcium binding protein A9 Homo sapiens 0-6 23829781-6 2013 The Sap2p prepropeptide coding sequence was linked to that of two mammalian calcium-binding proteins, S100A8 and S100A9, which are associated with symptomatic vaginal candidiasis. Calcium 76-83 S100 calcium binding protein A9 Homo sapiens 113-119 24595267-10 2014 The results also showed the calcium dependency in S100A8- and S100A9-evoked endothelial response, indicating that calcium dependency on formation of S100A8 or A9 dimmers might be the prerequisite for this endothelial functional alteration. Calcium 28-35 S100 calcium binding protein A9 Homo sapiens 62-68 24595267-10 2014 The results also showed the calcium dependency in S100A8- and S100A9-evoked endothelial response, indicating that calcium dependency on formation of S100A8 or A9 dimmers might be the prerequisite for this endothelial functional alteration. Calcium 114-121 S100 calcium binding protein A9 Homo sapiens 62-68 24156302-5 2013 We found that the CD85j receptor interacts with a calcium-binding proteins of the S100 family; namely, S100A9. Calcium 50-57 S100 calcium binding protein A9 Homo sapiens 103-109 23456298-1 2013 S100A8 and S100A9 (S100A8/A9) are low-molecular weight members of the S100 family of calcium-binding proteins. Calcium 85-92 S100 calcium binding protein A9 Homo sapiens 19-28 23483999-1 2013 Amyloid aggregates of the calcium-binding EF-hand proteins, S100A8 and S100A9, have been found in the corpora amylacea of patients with prostate cancer and may play a role in carcinogenesis. Calcium 26-33 S100 calcium binding protein A9 Homo sapiens 71-77 23123827-1 2013 S100A9 is a calcium binding protein with multiple ligands and post-translation modifications that is involved in inflammatory events and the initial development of the cancer cell through to the development of metastatic disease. Calcium 12-19 S100 calcium binding protein A9 Homo sapiens 0-6 22144572-1 2011 BACKGROUND: The calcium-binding proteins myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) form MRP-8/14 heterodimers (S100A8/A9, calprotectin) that regulate myeloid cell function and inflammatory responses and serve as early serum markers for monitoring acute allograft rejection. Calcium 16-23 S100 calcium binding protein A9 Homo sapiens 86-92 22691358-0 2012 [Expression and clinical significance of calcium-binding protein S100A9 in breast cancer]. Calcium 41-48 S100 calcium binding protein A9 Homo sapiens 65-71 22691358-1 2012 AIM: To investigate the expression and clinical significance of calcium-binding protein S100A9 in the patients of breast cancer. Calcium 65-72 S100 calcium binding protein A9 Homo sapiens 89-95 22808130-1 2012 S100A8 and S100A9 are two calcium binding Myeloid Related Proteins, and important mediators of inflammatory diseases. Calcium 26-33 S100 calcium binding protein A9 Homo sapiens 11-17 22144572-1 2011 BACKGROUND: The calcium-binding proteins myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) form MRP-8/14 heterodimers (S100A8/A9, calprotectin) that regulate myeloid cell function and inflammatory responses and serve as early serum markers for monitoring acute allograft rejection. Calcium 16-23 S100 calcium binding protein A9 Homo sapiens 94-100 21492422-2 2011 The heterodimer of the cytosolic calcium-binding proteins S100A8 and S100A9 (S100A8/A9) is secreted by activated polymorphonuclear neutrophils (PMNs) and monocytes and serves as a serum marker for several inflammatory diseases. Calcium 33-40 S100 calcium binding protein A9 Homo sapiens 69-75 21592353-1 2011 BACKGROUND: Myeloid-related protein 8/14 (MRP8/14) is a stable heterodimer formed by two different calcium-binding proteins (MRP8 and MRP14). Calcium 99-106 S100 calcium binding protein A9 Homo sapiens 134-139 21492422-2 2011 The heterodimer of the cytosolic calcium-binding proteins S100A8 and S100A9 (S100A8/A9) is secreted by activated polymorphonuclear neutrophils (PMNs) and monocytes and serves as a serum marker for several inflammatory diseases. Calcium 33-40 S100 calcium binding protein A9 Homo sapiens 77-86 20630697-3 2010 The calcium-binding proteins S100A8 and S100A9 are abundant cytosolic constituents of human neutrophils. Calcium 4-11 S100 calcium binding protein A9 Homo sapiens 40-46 20422274-1 2011 Calgranulin B is a small calcium-binding protein with several immunological functions mainly involved in chronic inflammation and cancer. Calcium 25-32 S100 calcium binding protein A9 Homo sapiens 0-13 17095618-1 2007 Activated phagocytes express considerable amounts of MRP8 and MRP14, 2 calcium-binding S100 proteins forming stable heterodimers that are specifically secreted at inflammatory sites in many diseases. Calcium 71-78 S100 calcium binding protein A9 Homo sapiens 62-67 19656587-4 2010 Here, we demonstrate that the calcium-binding protein S100A9, normally abundant in the cytoplasm of neutrophils and also released by apoptotic neutrophils, is involved in the suppression of macrophages after the uptake of apoptotic neutrophils. Calcium 30-37 S100 calcium binding protein A9 Homo sapiens 54-60 19656587-7 2010 Finally, we demonstrate that the calcium-binding property of S100A9 might play a role in the suppression process, since the stimulation of intracellular calcium release with ionomycin significantly reversed the effects of the uptake of apoptotic neutrophils in macrophages. Calcium 33-40 S100 calcium binding protein A9 Homo sapiens 61-67 19656587-7 2010 Finally, we demonstrate that the calcium-binding property of S100A9 might play a role in the suppression process, since the stimulation of intracellular calcium release with ionomycin significantly reversed the effects of the uptake of apoptotic neutrophils in macrophages. Calcium 153-160 S100 calcium binding protein A9 Homo sapiens 61-67 17429438-1 2007 The calcium- and arachidonic acid (AA)-binding proteins S100A8 and S100A9 are involved in nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation in phagocytes. Calcium 4-11 S100 calcium binding protein A9 Homo sapiens 67-73 19201880-1 2009 The S100 calcium-binding proteins S100A8 and S100A9 are elevated systemically in patients with viral infections. Calcium 9-16 S100 calcium binding protein A9 Homo sapiens 45-51 19079333-1 2009 Expressed by squamous mucosal keratinocytes, calprotectin is a complex of two EF-hand calcium-binding proteins of the S100 subfamily (S100A8 and S100A9) with significant antimicrobial activity. Calcium 86-93 S100 calcium binding protein A9 Homo sapiens 145-151 17636430-1 2007 S100A8 and S100A9 are calcium-binding proteins expressed in myeloid cells and are markers of numerous inflammatory diseases in humans. Calcium 22-29 S100 calcium binding protein A9 Homo sapiens 11-17 17197440-10 2007 We hypothesize that calcium binds to S100A8/S100A9 complexes and alters their composition, thus enabling S100A8 to interact with the telomerase complex and inhibit its activity. Calcium 20-27 S100 calcium binding protein A9 Homo sapiens 44-50 17050004-1 2006 S100A8 and S100A9 are two proinflammatory molecules belonging to the S100 family of calcium-binding proteins. Calcium 84-91 S100 calcium binding protein A9 Homo sapiens 11-17 17138858-1 2007 The calcium-binding proteins S100A8 and S100A9 and their heterocomplex calprotectin are abundant cytosolic constituents in human neutrophils, constitutively expressed by mucosal epithelium and in association with inflammation by epidermal keratinocytes. Calcium 4-11 S100 calcium binding protein A9 Homo sapiens 40-46 17237603-7 2007 Among the proteins, we focused on one of the up-regulated proteins, S100A9 calcium binding protein (S100A9), and investigated proteome changes brought by a recombinant S100A9 in a human synovial sarcoma cell line (SW982), a human chondrosarcoma cell line (OUMS-27), and a human T leukemia cell line (Jurkat). Calcium 75-82 S100 calcium binding protein A9 Homo sapiens 68-74 17237603-7 2007 Among the proteins, we focused on one of the up-regulated proteins, S100A9 calcium binding protein (S100A9), and investigated proteome changes brought by a recombinant S100A9 in a human synovial sarcoma cell line (SW982), a human chondrosarcoma cell line (OUMS-27), and a human T leukemia cell line (Jurkat). Calcium 75-82 S100 calcium binding protein A9 Homo sapiens 100-106 17237603-7 2007 Among the proteins, we focused on one of the up-regulated proteins, S100A9 calcium binding protein (S100A9), and investigated proteome changes brought by a recombinant S100A9 in a human synovial sarcoma cell line (SW982), a human chondrosarcoma cell line (OUMS-27), and a human T leukemia cell line (Jurkat). Calcium 75-82 S100 calcium binding protein A9 Homo sapiens 100-106 17050004-8 2006 Here we demonstrate for the first time by different biophysical methods (MALDI-MS, ESI-MS, fluorescence spectroscopy) that zinc-binding, like calcium, induces (S100A8/S100A9)(2)-tetramers. Calcium 142-149 S100 calcium binding protein A9 Homo sapiens 167-173 17050004-11 2006 Thus, like calcium, zinc acts as a regulatory factor in S100A8/S100A9-dependent signaling pathways. Calcium 11-18 S100 calcium binding protein A9 Homo sapiens 63-69 16191197-1 2005 BACKGROUND: Myeloid-related protein 8 (MRP8) and MRP14 are S100 family calcium binding proteins that form a heterodimer known as calprotectin or MRP8/14 that is present in the cytosol of neutrophils and monocytes. Calcium 71-78 S100 calcium binding protein A9 Homo sapiens 49-54 16327171-1 2005 S100A9 is a calcium binding protein found in high amounts in granulocytes and monocytes. Calcium 12-19 S100 calcium binding protein A9 Homo sapiens 0-6 16288014-2 2005 Here, we identify S100A7 (psoriasin), S100A8, and S100A9, members of the S100A family of calcium-binding proteins, as novel BRCA1-repressed targets. Calcium 89-96 S100 calcium binding protein A9 Homo sapiens 50-56 16792753-9 2006 CONCLUSIONS: Our data demonstrate that hyperproliferation and abnormal differentiation of psoriatic skin is associated with a massive upregulation and secretion of S100A8 and S100A9, suggesting not only a prominent role of these molecules during intracellular calcium-dependent signalling but also implying distinct extracellular functions. Calcium 260-267 S100 calcium binding protein A9 Homo sapiens 175-181 16690079-0 2006 Calcium-dependent tetramer formation of S100A8 and S100A9 is essential for biological activity. Calcium 0-7 S100 calcium binding protein A9 Homo sapiens 51-57 16690079-3 2006 The heterodimers of S100A8 and S100A9 represent the major calcium-binding proteins in phagocytes. Calcium 58-65 S100 calcium binding protein A9 Homo sapiens 31-37 16690079-5 2006 Calcium binding induces formation of (S100A8/S100A9)2 tetramers. Calcium 0-7 S100 calcium binding protein A9 Homo sapiens 45-51 16690079-7 2006 To investigate the importance of higher-order oligomerization for S100 proteins, we created a set of mutations within S100A9 (N69A, E78A, N69A+E78A) destroying the high-affinity C-terminal calcium-binding site (EF-hand II). Calcium 189-196 S100 calcium binding protein A9 Homo sapiens 118-124 16690079-9 2006 In contrast, mass spectrometric analysis and density gradient centrifugation revealed that calcium-induced association of (S100A8/S100A9)2 tetramers was strictly dependent on a functional EF-hand II in S100A9. Calcium 91-98 S100 calcium binding protein A9 Homo sapiens 130-136 16690079-9 2006 In contrast, mass spectrometric analysis and density gradient centrifugation revealed that calcium-induced association of (S100A8/S100A9)2 tetramers was strictly dependent on a functional EF-hand II in S100A9. Calcium 91-98 S100 calcium binding protein A9 Homo sapiens 202-208 16690079-11 2006 Thus, our data demonstrate that calcium-dependent formation of (S100A8/S100A9)2 tetramers is an essential prerequisite for biological function. Calcium 32-39 S100 calcium binding protein A9 Homo sapiens 71-77 12719414-3 2003 Myeloid-related proteins MRP8 and MRP14 of the S100 family are EF-hand calcium-binding proteins. Calcium 71-78 S100 calcium binding protein A9 Homo sapiens 34-39 15740587-4 2005 Using Western blot analysis and quantitative reverse transcriptase-polymerase chain reaction (RT-PCR), both S100A7 and S100A9 were shown to be induced in normal primary keratinocytes (HEKn), when differentiation was promoted by high extracellular calcium, loss of contact with extracellular matrix and confluent conditions, as previously reported for S100A7 in mammary epithelial cells. Calcium 247-254 S100 calcium binding protein A9 Homo sapiens 119-125 16259107-1 2005 S100A9, a calcium-binding protein, is associated with myeloid cell differentiation and is expressed in some adenocarcinomas as well as in squamous epithelia and squamous cell carcinoma. Calcium 10-17 S100 calcium binding protein A9 Homo sapiens 0-6 15304364-5 2004 S100A9 (MRP14) and S100A8 (MRP8) are translocated into detergent resistant lipid structures only after calcium activation of the neutrophils. Calcium 103-110 S100 calcium binding protein A9 Homo sapiens 0-6 15304364-5 2004 S100A9 (MRP14) and S100A8 (MRP8) are translocated into detergent resistant lipid structures only after calcium activation of the neutrophils. Calcium 103-110 S100 calcium binding protein A9 Homo sapiens 8-13 15040889-1 2004 Migration inhibitory factor-related protein 14 (MRP14) is one of calcium-binding proteins, referred as S100A9. Calcium 65-72 S100 calcium binding protein A9 Homo sapiens 0-46 15040889-1 2004 Migration inhibitory factor-related protein 14 (MRP14) is one of calcium-binding proteins, referred as S100A9. Calcium 65-72 S100 calcium binding protein A9 Homo sapiens 48-53 15040889-1 2004 Migration inhibitory factor-related protein 14 (MRP14) is one of calcium-binding proteins, referred as S100A9. Calcium 65-72 S100 calcium binding protein A9 Homo sapiens 103-109 15237925-3 2004 The small calcium binding protein S100A9 (MRP14) was identified as a discriminatory marker protein in SF by global proteomic analysis. Calcium 10-17 S100 calcium binding protein A9 Homo sapiens 34-40 15237925-3 2004 The small calcium binding protein S100A9 (MRP14) was identified as a discriminatory marker protein in SF by global proteomic analysis. Calcium 10-17 S100 calcium binding protein A9 Homo sapiens 42-47 12937135-0 2003 Expression of calcium-binding proteins MRP8 and MRP14 in inflammatory muscle diseases. Calcium 14-21 S100 calcium binding protein A9 Homo sapiens 48-53 12937135-3 2003 Expression of myeloid-related proteins MRP8 and MRP14, two calcium-binding S100-proteins, characterizes a proinflammatory subtype of macrophages. Calcium 59-66 S100 calcium binding protein A9 Homo sapiens 48-53 15927886-0 2005 Molecular basis of the complex formation between the two calcium-binding proteins S100A8 (MRP8) and S100A9 (MRP14). Calcium 57-64 S100 calcium binding protein A9 Homo sapiens 100-106 15927886-0 2005 Molecular basis of the complex formation between the two calcium-binding proteins S100A8 (MRP8) and S100A9 (MRP14). Calcium 57-64 S100 calcium binding protein A9 Homo sapiens 108-113 15613338-2 2005 Two S100 family calcium-binding proteins, macrophage inhibitory-related factor protein 8 (MRP-8) and MRP-14, form a protein complex, MRP-8/14, that inactivates CKII. Calcium 16-23 S100 calcium binding protein A9 Homo sapiens 101-107 15377837-3 2004 We show that expression of the calcium-binding protein S100A9 is strongly induced by OM in MCF-7 cells and this induction is markedly reduced in MCF-7-dnStat3 cells that express a dominant negative mutant of STAT3. Calcium 31-38 S100 calcium binding protein A9 Homo sapiens 55-61 14597726-7 2004 The correlation of MRP8 and MRP14 expression with disease activity indicates that these calcium-binding proteins are of pathophysiological relevance in GN. Calcium 88-95 S100 calcium binding protein A9 Homo sapiens 28-33 12719414-9 2003 Moreover, MRP8/MRP14 initiated oxidase activation on its own, through a calcium-dependent specific interaction with cytochrome b558 as shown by atomic force microscopy and a structure-function relationship investigation. Calcium 72-79 S100 calcium binding protein A9 Homo sapiens 15-20 12167632-1 2002 S100A9, also referred to as MRP14, is a calcium-binding protein whose expression is tightly regulated during differentiation of myeloid cells. Calcium 40-47 S100 calcium binding protein A9 Homo sapiens 0-6 12480428-1 2002 BACKGROUND: Calprotectin (complex of S100A8 and S100A9) is the major calcium and zinc-binding protein of phagocytes. Calcium 69-76 S100 calcium binding protein A9 Homo sapiens 48-54 12167632-1 2002 S100A9, also referred to as MRP14, is a calcium-binding protein whose expression is tightly regulated during differentiation of myeloid cells. Calcium 40-47 S100 calcium binding protein A9 Homo sapiens 28-33 12384771-4 2002 This cluster contains 13 genes encoding S100 calcium-binding proteins, some of which ( S100A7, S100A8 and S100A9) are known to be up-regulated in individual patient keratinocytes. Calcium 45-52 S100 calcium binding protein A9 Homo sapiens 106-112 12489193-0 2002 S100A8 and S100A9 calcium-binding proteins: localization within normal and cyclosporin A-induced overgrowth gingiva. Calcium 18-25 S100 calcium binding protein A9 Homo sapiens 11-17 12489193-1 2002 S100A8 and S100A9, also called myeloid related protein (MRP) 8 and 14, are calcium-binding proteins highly expressed in neutrophils, in which they play a key role in the inflammatory progression. Calcium 75-82 S100 calcium binding protein A9 Homo sapiens 11-17 11168370-2 2001 The S100 calcium-binding proteins MRP-8 (S100A8) and MRP-14 (S100A9) form a heterodimeric complex in the cytosol of monocyte and neutrophil cell types circulating in peripheral blood. Calcium 9-16 S100 calcium binding protein A9 Homo sapiens 53-59 11518789-1 2001 Upon interaction with activated endothelium, monocytes and neutrophils form complexes of myeloid-related protein 8 (MRP8) (S100A8) and MRP14 (S100A9), two members of the calcium-binding S100 family that are secreted during transendothelial migration. Calcium 170-177 S100 calcium binding protein A9 Homo sapiens 135-140 11518789-1 2001 Upon interaction with activated endothelium, monocytes and neutrophils form complexes of myeloid-related protein 8 (MRP8) (S100A8) and MRP14 (S100A9), two members of the calcium-binding S100 family that are secreted during transendothelial migration. Calcium 170-177 S100 calcium binding protein A9 Homo sapiens 142-148 11564187-0 2001 Selective expression of calcium-binding proteins S100a8 and S100a9 at distinct sites of hair follicles. Calcium 24-31 S100 calcium binding protein A9 Homo sapiens 60-66 11168370-2 2001 The S100 calcium-binding proteins MRP-8 (S100A8) and MRP-14 (S100A9) form a heterodimeric complex in the cytosol of monocyte and neutrophil cell types circulating in peripheral blood. Calcium 9-16 S100 calcium binding protein A9 Homo sapiens 61-67 10976885-0 2000 Calcium-induced noncovalently linked tetramers of MRP8 and MRP14 are confirmed by electrospray ionization-mass analysis. Calcium 0-7 S100 calcium binding protein A9 Homo sapiens 59-64 11058579-1 2000 The myeloid-related proteins MRP8 (S100A8) and MRP14 (S100A9), two members of the S100 family of calcium-binding proteins, are co-expressed and form a cell-surface and cytoskeleton-associated heterodimer upon calcium mobilization which is recognized by the mAb 27E10. Calcium 97-104 S100 calcium binding protein A9 Homo sapiens 47-52 11058579-1 2000 The myeloid-related proteins MRP8 (S100A8) and MRP14 (S100A9), two members of the S100 family of calcium-binding proteins, are co-expressed and form a cell-surface and cytoskeleton-associated heterodimer upon calcium mobilization which is recognized by the mAb 27E10. Calcium 97-104 S100 calcium binding protein A9 Homo sapiens 54-60 11058579-1 2000 The myeloid-related proteins MRP8 (S100A8) and MRP14 (S100A9), two members of the S100 family of calcium-binding proteins, are co-expressed and form a cell-surface and cytoskeleton-associated heterodimer upon calcium mobilization which is recognized by the mAb 27E10. Calcium 209-216 S100 calcium binding protein A9 Homo sapiens 47-52 11058579-1 2000 The myeloid-related proteins MRP8 (S100A8) and MRP14 (S100A9), two members of the S100 family of calcium-binding proteins, are co-expressed and form a cell-surface and cytoskeleton-associated heterodimer upon calcium mobilization which is recognized by the mAb 27E10. Calcium 209-216 S100 calcium binding protein A9 Homo sapiens 54-60 10976885-2 2000 MRP8, MRP14*, and MRP14, isolated from human granulocytes or monocytes, are known to form noncovalently associated complexes; the exact stoichiometries of these complexes in the presence of calcium are still controversially discussed in the literature. Calcium 190-197 S100 calcium binding protein A9 Homo sapiens 6-11 10976885-2 2000 MRP8, MRP14*, and MRP14, isolated from human granulocytes or monocytes, are known to form noncovalently associated complexes; the exact stoichiometries of these complexes in the presence of calcium are still controversially discussed in the literature. Calcium 190-197 S100 calcium binding protein A9 Homo sapiens 18-23 10976885-1 2000 Proteins of the S100- family such as MRP8 (S100A8) and MRP14 (S100A9)-and its isoform MRP14*-show two calcium-binding sites (EF hands) per protein chain. Calcium 102-109 S100 calcium binding protein A9 Homo sapiens 55-60 10976885-3 2000 The present electrospray ionization-mass spectrometry (ESI-MS) study shows that MRP8, MRP14*, and MRP14 exist as heterodimers MRP8/14* and MRP8/14, respectively, in the absence of calcium confirming both a recent nuclear magnetic resonance study and a biochemical study on this topic. Calcium 180-187 S100 calcium binding protein A9 Homo sapiens 86-91 10976885-3 2000 The present electrospray ionization-mass spectrometry (ESI-MS) study shows that MRP8, MRP14*, and MRP14 exist as heterodimers MRP8/14* and MRP8/14, respectively, in the absence of calcium confirming both a recent nuclear magnetic resonance study and a biochemical study on this topic. Calcium 180-187 S100 calcium binding protein A9 Homo sapiens 98-103 10976885-1 2000 Proteins of the S100- family such as MRP8 (S100A8) and MRP14 (S100A9)-and its isoform MRP14*-show two calcium-binding sites (EF hands) per protein chain. Calcium 102-109 S100 calcium binding protein A9 Homo sapiens 62-68 10976885-4 2000 Furthermore, this ESI-MS study confirms the previously published matrix-assisted laser desorption ionization (MALDI)-MS study, which states that the MRP8/14* and MRP8/14 heterodimeric complexes tetramerize to heterotetramers (MRP8/14*)2, (MRP8/14*)(MRP8/14), and (MRP8/14)2, respectively, in the presence of calcium. Calcium 308-315 S100 calcium binding protein A9 Homo sapiens 226-234 10976885-1 2000 Proteins of the S100- family such as MRP8 (S100A8) and MRP14 (S100A9)-and its isoform MRP14*-show two calcium-binding sites (EF hands) per protein chain. Calcium 102-109 S100 calcium binding protein A9 Homo sapiens 86-91 10536818-0 1999 Calcium-induced noncovalently linked tetramers of MRP8 and MRP14 detected by ultraviolet matrix-assisted laser desorption/ionization mass spectrometry. Calcium 0-7 S100 calcium binding protein A9 Homo sapiens 59-64 10612291-4 1999 Conversely, the expression of a novel variant of heat shock protein70 and several members of the S100 protein family of calcium-binding proteins (two isoforms of S100A9, S100A8, S100A11 and S100A6) were upregulated in transformed colon mucosa. Calcium 120-127 S100 calcium binding protein A9 Homo sapiens 162-168 10551823-0 1999 The two calcium-binding proteins, S100A8 and S100A9, are involved in the metabolism of arachidonic acid in human neutrophils. Calcium 8-15 S100 calcium binding protein A9 Homo sapiens 45-51 10728975-0 2000 Human gingival crevicular fluid contains MRP8 (S100A8) and MRP14 (S100A9), two calcium-binding proteins of the S100 family. Calcium 79-86 S100 calcium binding protein A9 Homo sapiens 59-64 10728975-0 2000 Human gingival crevicular fluid contains MRP8 (S100A8) and MRP14 (S100A9), two calcium-binding proteins of the S100 family. Calcium 79-86 S100 calcium binding protein A9 Homo sapiens 66-72 10536818-8 1999 Calcium-induced stabilization of the MRP8/MRP14 complexes was confirmed by DSC studies. Calcium 0-7 S100 calcium binding protein A9 Homo sapiens 42-47 10536818-1 1999 MRP8 and MRP14 are members of the S100 family of calcium-binding proteins which play an important role during calcium-induced activation of phagocytes. Calcium 49-56 S100 calcium binding protein A9 Homo sapiens 9-14 10536818-4 1999 In the present study we show for the first time by ultraviolet matrix-assisted laser desorption/ionization mass spectrometry (UV-MALDI-MS) the calcium-induced formation of noncovalently associated (MRP8/MRP14)2 tetramers. Calcium 143-150 S100 calcium binding protein A9 Homo sapiens 203-208 10536818-6 1999 MRP14 showed a higher affinity for calcium than MRP8. Calcium 35-42 S100 calcium binding protein A9 Homo sapiens 0-5 10399866-0 1999 Activation of macrophages/microglia with the calcium-binding proteins MRP14 and MRP8 is related to the lesional activities in the spinal cord of HTLV-I associated myelopathy. Calcium 45-52 S100 calcium binding protein A9 Homo sapiens 70-75 10464253-4 1999 S100A12, MRP8, and MRP14 translocate simultaneously from the cytosol to cytoskeletal and membrane structures in a calcium-dependent manner. Calcium 114-121 S100 calcium binding protein A9 Homo sapiens 19-24 10571075-1 1999 Analysis of the calcium-induced arachidonic acid (AA) binding to S100A8/A9 revealed that maximal AA binding was achieved at molar ratios of 1 mol S100A8 and 1 mol S100A9 and for values greater than 3 calciums per EF-hand. Calcium 16-23 S100 calcium binding protein A9 Homo sapiens 163-169 9920411-1 1998 The two migration inhibitory factor- (MIF)-related protein-8 (MRP8; S100A8) and MRP14 (S100A9) are two calcium-binding proteins of the S100 family. Calcium 103-110 S100 calcium binding protein A9 Homo sapiens 87-93 10344284-1 1999 The expression of calcium-binding protein S100A9 was investigated in 23 matched sets of colorectal carcinoma and normal colon mucosa using two-dimensional gel electrophoresis. Calcium 18-25 S100 calcium binding protein A9 Homo sapiens 42-48 9920411-1 1998 The two migration inhibitory factor- (MIF)-related protein-8 (MRP8; S100A8) and MRP14 (S100A9) are two calcium-binding proteins of the S100 family. Calcium 103-110 S100 calcium binding protein A9 Homo sapiens 80-85 9693055-1 1998 A method is described for purification of P6, MRP8, and MRP14, three calcium-binding proteins assigned to the S100 protein family. Calcium 69-76 S100 calcium binding protein A9 Homo sapiens 56-61 9083074-0 1997 A heterocomplex formed by the calcium-binding proteins MRP8 (S100A8) and MRP14 (S100A9) binds unsaturated fatty acids with high affinity. Calcium 30-37 S100 calcium binding protein A9 Homo sapiens 73-78 9570563-1 1998 The 14-kDa myeloid-related protein (MRP-14) and its heterodimeric partner, MRP-8, are members of the S100 family of calcium-binding proteins (S100A9 and S100A8, respectively). Calcium 116-123 S100 calcium binding protein A9 Homo sapiens 36-42 9083090-0 1997 Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. Calcium 43-50 S100 calcium binding protein A9 Homo sapiens 36-41 9083074-0 1997 A heterocomplex formed by the calcium-binding proteins MRP8 (S100A8) and MRP14 (S100A9) binds unsaturated fatty acids with high affinity. Calcium 30-37 S100 calcium binding protein A9 Homo sapiens 80-86 8898915-1 1996 The myeloid-related proteins MRP-14 and MRP-8 and also p6, three calcium-binding proteins of the S100 family, translocate to the membrane during human neutrophil activation with stimuli known to require extracellular calcium for activity. Calcium 217-224 S100 calcium binding protein A9 Homo sapiens 29-35 8989565-3 1997 As a marker for the activation of these "brain macrophages," we have used the macrophage inhibitor factor-related-proteins MRP-8 and MRP-14, which belong to the calcium binding S-100 protein family. Calcium 161-168 S100 calcium binding protein A9 Homo sapiens 133-139 8898915-4 1996 Three isoforms of MRP-14 were markedly phosphorylated in the membrane and in the cytosol upon activation with extracellular calcium-dependent stimuli, such as opsonized zymosan, the calcium ionophore A23187, N-formylmethionylleucylphenylalanine in the presence of cytochalasin B and arachidonic acid, or upon extracellular calcium-independent stimulation (PMA). Calcium 124-131 S100 calcium binding protein A9 Homo sapiens 18-24 8898915-4 1996 Three isoforms of MRP-14 were markedly phosphorylated in the membrane and in the cytosol upon activation with extracellular calcium-dependent stimuli, such as opsonized zymosan, the calcium ionophore A23187, N-formylmethionylleucylphenylalanine in the presence of cytochalasin B and arachidonic acid, or upon extracellular calcium-independent stimulation (PMA). Calcium 182-189 S100 calcium binding protein A9 Homo sapiens 18-24 8898915-4 1996 Three isoforms of MRP-14 were markedly phosphorylated in the membrane and in the cytosol upon activation with extracellular calcium-dependent stimuli, such as opsonized zymosan, the calcium ionophore A23187, N-formylmethionylleucylphenylalanine in the presence of cytochalasin B and arachidonic acid, or upon extracellular calcium-independent stimulation (PMA). Calcium 182-189 S100 calcium binding protein A9 Homo sapiens 18-24 8934661-1 1996 Mac 387, a murine mAb, was previously described to detect a complex form of MRP-14 and MRP-8, two calcium-binding proteins of the S100 family, but recent experiments suggested that Mac 387 recognized only MRP-14. Calcium 98-105 S100 calcium binding protein A9 Homo sapiens 0-7 8645219-1 1996 MRP14 (macrophage migration-inhibitory factor-related protein of molecular mass 14 kDa) is an S100 calcium binding protein constitutively expressed in human neutrophils which may be associated with cellular activation/inflammation. Calcium 99-106 S100 calcium binding protein A9 Homo sapiens 0-5 8934661-1 1996 Mac 387, a murine mAb, was previously described to detect a complex form of MRP-14 and MRP-8, two calcium-binding proteins of the S100 family, but recent experiments suggested that Mac 387 recognized only MRP-14. Calcium 98-105 S100 calcium binding protein A9 Homo sapiens 181-188 8624844-1 1996 Calgranulin A (CAGA) and calgranulin B (CAGB) are two S100-like calcium-binding proteins that in human, bovine and mouse granulocytes are associated into a heterocomplex. Calcium 64-71 S100 calcium binding protein A9 Homo sapiens 25-38 8964612-1 1996 We developed a quantitative enzyme immunoassay for human MRP-8/MRP-14, neutrophil cytosolic proteins with calcium-binding and bacteriastatic properties. Calcium 106-113 S100 calcium binding protein A9 Homo sapiens 63-69 8558004-10 1996 This might be caused by altered calcium binding, and indeed, using isoelectric focusing and 45Ca2+ overlay the MRP14 band containing phosphorylated MRP14 revealed increased Ca2+ binding compared with bands containing other MRP14 isoforms. Calcium 32-39 S100 calcium binding protein A9 Homo sapiens 111-116 8624844-13 1996 Unlike the homodimer, CAGA/CAGB was bound to a Phenyl Superose column in a calcium-dependent manner. Calcium 75-82 S100 calcium binding protein A9 Homo sapiens 27-31 8624844-1 1996 Calgranulin A (CAGA) and calgranulin B (CAGB) are two S100-like calcium-binding proteins that in human, bovine and mouse granulocytes are associated into a heterocomplex. Calcium 64-71 S100 calcium binding protein A9 Homo sapiens 40-44 7762618-1 1995 A complex of two calcium binding proteins, MRP8 [also called cystic fibrosis (CF) antigen] and MRP14, proteins known to be expressed in cells of myeloid origin, has been shown to be present in higher amounts in the serum of CF patients and heterozygotes compared with normal subjects. Calcium 17-24 S100 calcium binding protein A9 Homo sapiens 95-100 7542868-0 1995 Increase of calcium levels in epithelial cells induces translocation of calcium-binding proteins migration inhibitory factor-related protein 8 (MRP8) and MRP14 to keratin intermediate filaments. Calcium 12-19 S100 calcium binding protein A9 Homo sapiens 154-159 7890287-0 1995 Immunohistochemical demonstration of the calcium-binding proteins MRP8 and MRP14 and their heterodimer (27E10 antigen) in Crohn"s disease. Calcium 41-48 S100 calcium binding protein A9 Homo sapiens 75-80 8120141-3 1994 Depending on the state of activation, microglia become positive for the myeloid cell-specific calcium binding protein MRP14, LCA with CD45RO determinant, interferon-alpha, and an antigen recognized by monoclonal antibody 27E10. Calcium 94-101 S100 calcium binding protein A9 Homo sapiens 118-123 7829973-0 1995 Heterodimers of the calcium-binding proteins MRP8 and MRP14 are expressed on the surface of human monocytes upon adherence to fibronectin and collagen. Calcium 20-27 S100 calcium binding protein A9 Homo sapiens 54-59 8053890-0 1994 Expression of the calcium-binding proteins MRP8 and MRP14 in monocytes is regulated by a calcium-induced suppressor mechanism. Calcium 18-25 S100 calcium binding protein A9 Homo sapiens 52-57 8053890-0 1994 Expression of the calcium-binding proteins MRP8 and MRP14 in monocytes is regulated by a calcium-induced suppressor mechanism. Calcium 89-96 S100 calcium binding protein A9 Homo sapiens 52-57 8053890-1 1994 MRP8 and MRP14 are two calcium-binding proteins of the S-100 family the expression of which is restricted to distinct stages of monocytic differentiation. Calcium 23-30 S100 calcium binding protein A9 Homo sapiens 9-14 8053890-6 1994 Elevation of intracellular calcium levels by A23187, as well as by thapsigargin, was found to lead to specific down-regulation of MRP8/MRP14 mRNA which is in contrast with data reported for inflammatory factors such as interleukin-1 or tumour necrosis factor alpha. Calcium 27-34 S100 calcium binding protein A9 Homo sapiens 135-140 8053890-8 1994 Finally, we demonstrated that calcium-mediated down-regulation of MRP8-MRP14 can be antagonized by cycloheximide, suggesting that a calcium-induced repressor protein is responsible for suppression of MRP8-MRP14 at the transcriptional level. Calcium 30-37 S100 calcium binding protein A9 Homo sapiens 71-76 8053890-8 1994 Finally, we demonstrated that calcium-mediated down-regulation of MRP8-MRP14 can be antagonized by cycloheximide, suggesting that a calcium-induced repressor protein is responsible for suppression of MRP8-MRP14 at the transcriptional level. Calcium 30-37 S100 calcium binding protein A9 Homo sapiens 205-210 8053890-8 1994 Finally, we demonstrated that calcium-mediated down-regulation of MRP8-MRP14 can be antagonized by cycloheximide, suggesting that a calcium-induced repressor protein is responsible for suppression of MRP8-MRP14 at the transcriptional level. Calcium 132-139 S100 calcium binding protein A9 Homo sapiens 71-76 8053890-8 1994 Finally, we demonstrated that calcium-mediated down-regulation of MRP8-MRP14 can be antagonized by cycloheximide, suggesting that a calcium-induced repressor protein is responsible for suppression of MRP8-MRP14 at the transcriptional level. Calcium 132-139 S100 calcium binding protein A9 Homo sapiens 205-210 7517672-0 1994 Increased coexpression of CFTR and S100 calcium binding proteins MRP8 and MRP14 mRNAs in cystic fibrosis human tracheal gland cells. Calcium 40-47 S100 calcium binding protein A9 Homo sapiens 74-79 8440321-1 1993 The calcium-binding proteins MRP8 and MRP14 present in mature monomyelocytic cells are induced during differentiation and may mediate the growth arrest in differentiating HL-60 cells. Calcium 4-11 S100 calcium binding protein A9 Homo sapiens 38-43 7507970-2 1994 MAC387 has been described to show a similar reaction pattern as antisera to a complex formed by the calcium-binding proteins MRP8 and MRP14. Calcium 100-107 S100 calcium binding protein A9 Homo sapiens 0-6 7507970-2 1994 MAC387 has been described to show a similar reaction pattern as antisera to a complex formed by the calcium-binding proteins MRP8 and MRP14. Calcium 100-107 S100 calcium binding protein A9 Homo sapiens 134-139 8400238-0 1993 MRP8 and MRP14, S-100-like proteins associated with myeloid differentiation, are translocated to plasma membrane and intermediate filaments in a calcium-dependent manner. Calcium 145-152 S100 calcium binding protein A9 Homo sapiens 9-14 8384844-0 1993 Expression of calcium-binding proteins MRP8 and MRP14 is associated with distinct monocytic differentiation pathways in HL-60 cells. Calcium 14-21 S100 calcium binding protein A9 Homo sapiens 48-53 8384844-1 1993 MRP8 and MRP14 are two calcium-binding proteins of the S-100 family which are expressed during distinct stages of monocytic maturation. Calcium 23-30 S100 calcium binding protein A9 Homo sapiens 9-14 8384844-5 1993 Western blot analysis revealed that formation of MRP8/MRP14 to biologically active complexes which has previously been shown to be a calcium-mediated process is not dependent on the differentiation stages of HL-60 cells. Calcium 133-140 S100 calcium binding protein A9 Homo sapiens 54-59 8071083-0 1994 Ultrastructural localization of the S-100-like proteins MRP8 and MRP14 in monocytes is calcium-dependent. Calcium 87-94 S100 calcium binding protein A9 Homo sapiens 65-70 1478921-0 1992 Regulation of myeloid-specific calcium binding protein synthesis by cytosolic protein kinase C. Two calcium binding proteins, MRP-8 and MRP-14, are specifically synthesized in human myeloid cells. Calcium 31-38 S100 calcium binding protein A9 Homo sapiens 136-142 1490735-2 1992 The CF-antigen has been shown to consist of the two calcium-binding proteins MRP8 and MRP14. Calcium 52-59 S100 calcium binding protein A9 Homo sapiens 86-91 8445331-3 1993 Both MRP-8 and MRP-14 display features characteristic of members of the S100 family of calcium-binding proteins. Calcium 87-94 S100 calcium binding protein A9 Homo sapiens 15-21 1373330-1 1992 MRP8 and MRP14 are two S100-like calcium-binding proteins of unknown function, associated with numbers of human inflammatory disorders. Calcium 33-40 S100 calcium binding protein A9 Homo sapiens 9-14 1378023-0 1992 The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions. Calcium 4-11 S100 calcium binding protein A9 Homo sapiens 38-43 26998104-1 2016 S100A8 and S100A9 are calcium-binding proteins that are secreted primarily by granulocytes and monocytes, and are upregulated during the inflammatory response. Calcium 22-29 S100 calcium binding protein A9 Homo sapiens 11-17 1524561-0 1992 The calcium binding proteins MRP8 and MRP14 in acute and chronic inflammation. Calcium 4-11 S100 calcium binding protein A9 Homo sapiens 38-43 2212622-1 1990 Mac387 monoclonal antibody (MAb) recognizes two calcium binding, myeloid-associated proteins, now termed calgranulins, expressed at high levels by neutrophils and monocytes. Calcium 48-55 S100 calcium binding protein A9 Homo sapiens 0-6 2199095-0 1990 Differential expression of the calcium-binding proteins MRP8 and MRP14 in granulomatous conditions: an immunohistochemical study. Calcium 31-38 S100 calcium binding protein A9 Homo sapiens 65-70 2199095-1 1990 MRP14 and MRP8 are well-characterized calcium-binding proteins present in myeloid cells and mononuclear phagocytes. Calcium 38-45 S100 calcium binding protein A9 Homo sapiens 0-5 1288418-1 1992 The expression of the heterodimeric complex of the calcium-binding proteins MRP-8 and MRP-14 was investigated in various inflammatory dermatoses using immunohistochemical staining with the monoclonal antibody 27E10. Calcium 51-58 S100 calcium binding protein A9 Homo sapiens 86-92 2071612-0 1991 Calcium-dependent complex assembly of the myeloic differentiation proteins MRP-8 and MRP-14. Calcium 0-7 S100 calcium binding protein A9 Homo sapiens 85-91 2071612-1 1991 MRP-8 and MRP-14 are calcium-binding proteins belonging to the S-100 protein family which have been shown to be associated with specific stages of myeloic/monocytic cell differentiation. Calcium 21-28 S100 calcium binding protein A9 Homo sapiens 10-16 33801279-3 2021 In particular, S100A8 and S100A9 in monomeric, homodimeric, or heterodimeric forms are able to modulate the survival and the sensitivity to chemotherapy of leukemic clones through their action on the regulation of intracellular calcium, on oxidative stress, on the activation of apoptosis, and thanks to their implications, on cell death regulation by autophagy and pyroptosis. Calcium 228-235 S100 calcium binding protein A9 Homo sapiens 26-32 34519180-4 2021 S100A9 is a calcium-binding protein implicated in tumor metastasis, progression, and aggressiveness that modulates the tumor microenvironment into an immunosuppressive state. Calcium 12-19 S100 calcium binding protein A9 Homo sapiens 0-6 34614509-3 2021 Using transcriptomic analyses and functional validation studies, we identified the calcium-binding proteins, S100A8 and S100A9 (S100A8/A9), as contributors to gilteritinib resistance in FLT3-ITD+ AML. Calcium 83-90 S100 calcium binding protein A9 Homo sapiens 120-126 34614509-3 2021 Using transcriptomic analyses and functional validation studies, we identified the calcium-binding proteins, S100A8 and S100A9 (S100A8/A9), as contributors to gilteritinib resistance in FLT3-ITD+ AML. Calcium 83-90 S100 calcium binding protein A9 Homo sapiens 128-137 34154976-3 2021 The objective of this study was to clarify whether S100A8 and S100A9, which are calcium-binding proteins mainly produced by activated neutrophils, are significant prognostic biomarkers in AE-IPF. Calcium 80-87 S100 calcium binding protein A9 Homo sapiens 62-68 34681835-2 2021 S100A8 and S100A9 are calcium-binding proteins playing essential roles in the regulation of inflammation and fibrous tissue formation, and they might modulate the paracrine effect of hMSCs. Calcium 22-29 S100 calcium binding protein A9 Homo sapiens 11-17 34376762-5 2021 The analysis yielded seven SARS-CoV-2 specific genes including CSF2 (GM-CSF) (colony-stimulating factor 2) and calcium-binding proteins (such as S100A8 and S100A9), which are known to be involved in respiratory diseases. Calcium 111-118 S100 calcium binding protein A9 Homo sapiens 156-162 35129008-4 2022 Results showed that the intracellular Ca2+ chelator, BAPTA, could completely inhibit 50-Hz MF-induced cell proliferation, whereas NIF, the inhibitor of L-type calcium channel, only partly blocked it. Calcium 159-166 S100 calcium binding protein A9 Homo sapiens 130-133 35217896-2 2022 In the current study, the involvement of S100 calcium binding protein S100A4, S100A9, and S100A10 in the inflammatory settings of COVID-19 patients were evaluated. Calcium 46-53 S100 calcium binding protein A9 Homo sapiens 78-84 34360737-4 2021 S100A9 is a calcium-binding, pro-inflammation protein, which is also found in such amyloid plaques. Calcium 12-19 S100 calcium binding protein A9 Homo sapiens 0-6 35390134-3 2022 We found 2 small intracellular calcium-sensing molecules, S100A8 and S100A9, among the top genes being upregulated in primary AML blasts upon stromal contact. Calcium 31-38 S100 calcium binding protein A9 Homo sapiens 69-75