PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31841141-0	2021	RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes.	Calcium	46-50	gap junction protein, alpha 3	Mus musculus	15-19	
31841141-11	2021	TRANSLATIONAL PERSPECTIVE: We here provide detailed evidence that Cx43 hemichannels can be opened by concomitant RyR activation and [Ca2+]i elevation, two fundamental players in cardiomyocyte excitation-contraction coupling.	Calcium	133-137	gap junction protein, alpha 3	Mus musculus	66-70	
31841141-12	2021	Recent work in a plakophillin-2 deficient mouse model for ARVC indicated RyR2-linked Ca2+ dysregulations that were suppressed by the Cx43 hemichannel inhibitor Gap19.	Calcium	85-89	gap junction protein, alpha 3	Mus musculus	133-137	
31841141-13	2021	Our present work delineates the necessary conditions to activate Cx43 hemichannels in RyR2- and Ca2+-dependent manners and provides a new peptide tool, RyRHCIp, that inhibits hemichannel opening by acting at this crucial RyR-hemichannel axis.	Calcium	96-100	gap junction protein, alpha 3	Mus musculus	65-69	
22033928-6	2011	Here we demonstrate that Cx43 hemichannels, but not CD38, import cADPR to increase intracellular calcium through RyR.	Calcium	97-104	gap junction protein, alpha 3	Mus musculus	25-29	
22033928-7	2011	We also demonstrate that physiological stimulation such as Fcgamma receptor (FcgammaR) ligation induces calcium mobilization through three sequential steps, Cx43-mediated NAD(+) export, CD38-mediated generation of cADPR and Cx43-mediated cADPR import in J774 cells.	Calcium	104-111	gap junction protein, alpha 3	Mus musculus	157-161	
22033928-7	2011	We also demonstrate that physiological stimulation such as Fcgamma receptor (FcgammaR) ligation induces calcium mobilization through three sequential steps, Cx43-mediated NAD(+) export, CD38-mediated generation of cADPR and Cx43-mediated cADPR import in J774 cells.	Calcium	104-111	gap junction protein, alpha 3	Mus musculus	224-228	
22033928-10	2011	Cx43 knockdown blocked extracellular cADPR import and extracellular cADPR-induced calcium mobilization in J774 cells.	Calcium	82-89	gap junction protein, alpha 3	Mus musculus	0-4	
34465795-6	2021	This study indicates that the spatial and temporal calcium precipitation is an age-related event associated with age-related nuclear cataract formation in Cx46KO mice, and further suggests that the loss of Cx46 promotes calcium precipitates in the lens core, which is a new mechanism that likely contributes to the pathological light scattering in this age-related cataract model.	Calcium	51-58	gap junction protein, alpha 3	Mus musculus	155-159	
34465795-6	2021	This study indicates that the spatial and temporal calcium precipitation is an age-related event associated with age-related nuclear cataract formation in Cx46KO mice, and further suggests that the loss of Cx46 promotes calcium precipitates in the lens core, which is a new mechanism that likely contributes to the pathological light scattering in this age-related cataract model.	Calcium	51-58	gap junction protein, alpha 3	Mus musculus	206-210	
34465795-6	2021	This study indicates that the spatial and temporal calcium precipitation is an age-related event associated with age-related nuclear cataract formation in Cx46KO mice, and further suggests that the loss of Cx46 promotes calcium precipitates in the lens core, which is a new mechanism that likely contributes to the pathological light scattering in this age-related cataract model.	Calcium	220-227	gap junction protein, alpha 3	Mus musculus	206-210	
22033928-11	2011	Cx43 overexpression in Cx43-negative cells conferred extracellular cADPR-induced calcium mobilization by the mediation of cADPR import.	Calcium	81-88	gap junction protein, alpha 3	Mus musculus	0-4	
22033928-11	2011	Cx43 overexpression in Cx43-negative cells conferred extracellular cADPR-induced calcium mobilization by the mediation of cADPR import.	Calcium	81-88	gap junction protein, alpha 3	Mus musculus	23-27	
22033928-12	2011	Our data suggest that Cx43 has a dual function exporting NAD(+) and importing cADPR into the cell to activate intracellular calcium mobilization.	Calcium	124-131	gap junction protein, alpha 3	Mus musculus	22-26	
17665084-7	2007	We also found that both SEMA3F and Cx43 moved from the cytoplasm to the plasma membrane in a mouse papilloma cell line when E-cadherin became functional after transferring the cells from low- to high-calcium conditions.	Calcium	200-207	gap junction protein, alpha 3	Mus musculus	35-39	
14622192-4	2003	In astrocytes, deletion of Cx43-coding DNA led to attenuated gap junctional coupling and impaired propagation of calcium waves, known to influence neuronal activity.	Calcium	113-120	gap junction protein, alpha 3	Mus musculus	27-31	
9700490-0	1998	Calcium waves between astrocytes from Cx43 knockout mice.	Calcium	0-7	gap junction protein, alpha 3	Mus musculus	38-42	
9302074-11	1997	These results suggest that gap junctional intercellular communication mediated by Cx43 is not critical for astrocyte differentiation but is likely involved in the regulation of intercellular calcium signaling and cell growth.	Calcium	191-198	gap junction protein, alpha 3	Mus musculus	82-86