PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9062551-4 1995 When comparing women affected by PIH with HPW, we observed (i) reduced Na+/K+ ATPase activity and enhanced Ca2+ ATPase activity and intraplatelet calcium concentrations, (ii) an increased membrane fluidity, (iii) an increased cholesterol concentration and ratio between unsaturated and saturated fatty acids, (iv) a reduction of the IMP number and the DF. Calcium 146-153 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 33-36 10027129-0 1998 Calcium supplementation in pregnancy to prevent pregnancy induced hypertension (PIH). Calcium 0-7 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 80-83 10027129-2 1998 The findings showed the lowering of blood pressure and prevention of PIH in those receiving Calcium Supplementation. Calcium 92-99 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 69-72 10027129-6 1998 The objective of this review is to show the rationale for supplementation of calcium during pregnancy to prevent PIH, hence the discussion on the latest investigations regarding etiology of PIH and the relation of Calcium to this causation. Calcium 77-84 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 113-116 10027129-10 1998 The conclusion of this review is Calcium supplementation helps those with high risk to develop PIH especially in countries where the calcium intake is low. Calcium 33-40 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 95-98 9596863-1 1997 OBJECTIVE: To evaluate the magnesium and calcium concentration of peripheral serum and mononuclear in patients with pregnancy induced hypertension (PIH). Calcium 41-48 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 148-151 9596863-5 1997 CONCLUSION: The decrease of magnesium and calcium concentration may be one of the important factors responsible for the pathophysiologic changes of PIH. Calcium 42-49 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 148-151 9289428-5 1996 It was stated that due to renal impairment observed during PIH, calcium urine excretion and calcium concentration in blood serum are decreased while serum inorganic phosphorus levels are increased. Calcium 64-71 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 59-62 9289428-5 1996 It was stated that due to renal impairment observed during PIH, calcium urine excretion and calcium concentration in blood serum are decreased while serum inorganic phosphorus levels are increased. Calcium 92-99 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 59-62 10799415-1 2000 The evidence that calcium plays a role in the etiology, prevention, and treatment of pregnancy-induced hypertension (PIH) is reviewed. Calcium 18-25 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 117-120 10799415-3 2000 Epidemiologic data suggest an inverse correlation between dietary calcium intake and incidence of PIH. Calcium 66-73 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 98-101 10799415-6 2000 However, high-risk groups, such as pregnant teens, populations with inadequate calcium intake, and women at risk of developing PIH, may benefit from consuming additional dietary calcium. Calcium 178-185 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 127-130 11479954-1 1999 OBJECTIVE: To assess the efficacy of urinary calcium and albumin output in 24 hours for prediction of the occurrence of pregnancy induced hypertension (PIH). Calcium 45-52 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 152-155 11479954-5 1999 RESULTS: The patients in whom PIH developed later (n = 14) had significant lower urinary calcium excretion [(1.43 +/- 0.37) mmol/24 h VS (3.26 +/- 0.75) mmol/24 h] and higher microalbuminuria [(12.68 +/- 6.81) micrograms/24 h VS (6.08 +/- 3.48) micrograms/24 h] as compared with the group which remained normal (n = 84). Calcium 89-96 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 30-33 10806665-1 1998 OBJECTIVE: To study the changes of calcium and magnesium levels in patients with pregnancy induced hypertension (PIH) and the therapeutic effect of magnesium sulfate (MgSO4). Calcium 35-42 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 113-116 10806665-3 1998 RESULT: Plasma calcium decreased significantly in moderate and severe PIH patients, but calcium increased and magnesium decreased in their erythrocytes. Calcium 15-22 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 70-73 9070385-3 1996 Specifically, clinical studies have shown that supplementation with calcium can significantly reduce the frequency of PIH, especially in populations with a low calcium intake. Calcium 68-75 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 118-121 9070385-3 1996 Specifically, clinical studies have shown that supplementation with calcium can significantly reduce the frequency of PIH, especially in populations with a low calcium intake. Calcium 160-167 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 118-121 9070385-4 1996 We have suggested that, in such a population, calcium supplementation is a safe and effective measure for reducing the incidence of PIH. Calcium 46-53 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 132-135 9070385-5 1996 Calcium supplementation reduces the risk of PIH by maintaining the serum ionized calcium level which is crucial for the production of endothelial nitric oxide, the increased generation of which maintains the vasodilatation that is characteristic of normal pregnancy. Calcium 0-7 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 44-47 9070385-5 1996 Calcium supplementation reduces the risk of PIH by maintaining the serum ionized calcium level which is crucial for the production of endothelial nitric oxide, the increased generation of which maintains the vasodilatation that is characteristic of normal pregnancy. Calcium 81-88 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 44-47 8151605-8 1994 The reduction of the antioxidant buffering level could account for several important pathophysiological features of PIH, such as the elevation of intracellular calcium, decreased red blood cell deformability and endothelial damage. Calcium 160-167 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 116-119 8745492-1 1995 OBJECTIVE: To study the predictive value of urinary calcium excretion on occurrence of pregnancy-induced hypertension (PIH). Calcium 52-59 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 119-122 8745492-4 1995 3 mmol/L of urinary calcium concentration and 0.04 of Ca/Cr ratio were chosen as predictive thresholds for development of PIH, with sensitivity of 76.2%, 81.0% and specificity of 97.5%, 98.2% respectively. Calcium 20-27 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 122-125 8745492-5 1995 CONCLUSIONS: Low urinary calcium excretion is a valuable marker for prediction of PIH. Calcium 25-32 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 82-85 8524183-3 1995 Specifically, clinical studies have shown that supplementation with calcium can significantly reduce the frequency of PIH, specially in populations with a low calcium intake. Calcium 68-75 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 118-121 8524183-3 1995 Specifically, clinical studies have shown that supplementation with calcium can significantly reduce the frequency of PIH, specially in populations with a low calcium intake. Calcium 159-166 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 118-121 8524183-4 1995 We have suggested that, in such a population, calcium supplementation is a safe and effective measure for reducing the frequency of PIH. Calcium 46-53 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 132-135 8524183-5 1995 Thus, the purpose of this article is to advance a hypothesis about the mechanism by which calcium supplementation reduces the risk of PIH. Calcium 90-97 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 134-137 8524183-6 1995 We propose that dietary calcium supplementation reduces the frequency of PIH by maintaining the serum ionized calcium level which is crucial for the production of endothelial nitric oxide, the increased generation of which maintains the vasodilatation that is characteristic of normal pregnancy. Calcium 24-31 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 73-76 8524183-6 1995 We propose that dietary calcium supplementation reduces the frequency of PIH by maintaining the serum ionized calcium level which is crucial for the production of endothelial nitric oxide, the increased generation of which maintains the vasodilatation that is characteristic of normal pregnancy. Calcium 110-117 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 73-76 8590367-0 1995 Prevention of pregnancy-induced hypertension by calcium dietary supplement: a preliminary report. Calcium 48-55 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 14-44 8590367-1 1995 OBJECTIVE: The purpose of this study is to clarify whether the taking of a calcium dietary supplement is able to prevent the development of pregnancy-induced hypertension (PIH) in Japanese people. Calcium 75-82 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 140-170 8590367-1 1995 OBJECTIVE: The purpose of this study is to clarify whether the taking of a calcium dietary supplement is able to prevent the development of pregnancy-induced hypertension (PIH) in Japanese people. Calcium 75-82 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 172-175 7752984-3 1995 Significantly lower serum total calcium, urinary calcium and magnesium excretions and plasma renin activity were evident in women with PIH. Calcium 32-39 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 135-138 7752984-3 1995 Significantly lower serum total calcium, urinary calcium and magnesium excretions and plasma renin activity were evident in women with PIH. Calcium 49-56 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 135-138 7712843-7 1995 Supplementation of 2g of calcium daily showed significant results in lowering the incidence of PIH (P < 0.05) without any adverse effects. Calcium 25-32 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 95-98 7712843-9 1995 200 cases with intake of 2g calcium were compared with corresponding non-calcium supplementation cases, and the incidence of PIH was 7.5% and 16.5% (P < 0.005) respectively. Calcium 28-35 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 125-128 7712843-10 1995 Mediating parathyroid hormone and renin activity are thought to be the effect of calcium on decreasing the incidence of PIH. Calcium 81-88 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 120-123 8590367-6 1995 The urinary excretion of sodium and calcium and serum free calcium at the 28th GW were much lower in a woman with PIH, despite of the taking of a calcium supplement, than in the normotensive calcium group. Calcium 36-43 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 114-117 8590367-6 1995 The urinary excretion of sodium and calcium and serum free calcium at the 28th GW were much lower in a woman with PIH, despite of the taking of a calcium supplement, than in the normotensive calcium group. Calcium 59-66 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 114-117 8590367-6 1995 The urinary excretion of sodium and calcium and serum free calcium at the 28th GW were much lower in a woman with PIH, despite of the taking of a calcium supplement, than in the normotensive calcium group. Calcium 59-66 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 114-117 8590367-6 1995 The urinary excretion of sodium and calcium and serum free calcium at the 28th GW were much lower in a woman with PIH, despite of the taking of a calcium supplement, than in the normotensive calcium group. Calcium 59-66 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 114-117 8590367-7 1995 Also, the parathyroid hormone level at the 28th GW was higher in the calcium-taking woman with PIH than in the normotensive calcium group. Calcium 69-76 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 95-98 8590367-8 1995 CONCLUSION: Our preliminary study suggests that among the possible effects of taking a calcium supplement are a decrease in blood pressure and the prevention of PIH in Japanese people, and that calcium metabolism might be related to the development of PIH. Calcium 87-94 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 161-164 8590367-8 1995 CONCLUSION: Our preliminary study suggests that among the possible effects of taking a calcium supplement are a decrease in blood pressure and the prevention of PIH in Japanese people, and that calcium metabolism might be related to the development of PIH. Calcium 87-94 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 252-255 8590367-8 1995 CONCLUSION: Our preliminary study suggests that among the possible effects of taking a calcium supplement are a decrease in blood pressure and the prevention of PIH in Japanese people, and that calcium metabolism might be related to the development of PIH. Calcium 194-201 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 252-255 8187916-8 1994 This increased immunologic activity is in accordance with some important changes seen in PIH, such as an increase in intracellular calcium, the presence of blood-borne mitogenic factor and a decrease in prostaglandin E series. Calcium 131-138 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 89-92 8313732-1 1993 In this paper the relationship between calcium and pregnancy induced hypertension (PIH) was prospectively studied. Calcium 39-46 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 83-86 8313732-9 1993 Supplement of calcium during pregnancy may benefit by reduction of PIH incidence. Calcium 14-21 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 67-70 1818715-4 1991 Elucidation of the pathophysiology of PIH has been enhanced by investigations of altered platelet calcium metabolism, the renin-aldosterone-angiotensin system, and other potent vasopressors. Calcium 98-105 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 38-41 8343236-5 1993 Correlative studies showed PIH having a negative correlation between blood pressure and plasma corrected calcium (r = -0.43, P < .05), which is in agreement with epidemiological studies of essential hypertension. Calcium 105-112 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 27-30 1460361-4 1992 In the primiparous group with no family history 58% of the patients with a low calcium/creatine ratio eventually developed PIH. Calcium 79-86 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 123-126 1460361-5 1992 Using a receiver operator curve, we calculated a predictive threshold calcium value for PIH of 0.06 at six month"s pregnancy. Calcium 70-77 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 88-91 1460361-6 1992 Thus urinary calcium excretion may be a useful early marker for PIH. Calcium 13-20 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 64-67 1639963-3 1992 PIH has been postulated to be the end result of endothelial cell damage and aberrant calcium metabolism. Calcium 85-92 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 0-3 1542820-8 1992 The efficacy and the potential advantages of this oral calcium antagonist, as shown in these preliminary findings, should stimulate further controlled investigation of this agent in PIH. Calcium 55-62 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 182-185 1783100-11 1991 These data suggest that the increase of p-[Ca2+]i and r-[Na+]i in PIH is important in the initiation and maintenance of hypertension by influencing peripheral vascular resistance, and also various factors in the serum of PIH women may contribute to the accumulation of intracellular ionized calcium in patients with PIH. Calcium 291-298 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 66-69 1783100-11 1991 These data suggest that the increase of p-[Ca2+]i and r-[Na+]i in PIH is important in the initiation and maintenance of hypertension by influencing peripheral vascular resistance, and also various factors in the serum of PIH women may contribute to the accumulation of intracellular ionized calcium in patients with PIH. Calcium 291-298 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 221-224 1783100-11 1991 These data suggest that the increase of p-[Ca2+]i and r-[Na+]i in PIH is important in the initiation and maintenance of hypertension by influencing peripheral vascular resistance, and also various factors in the serum of PIH women may contribute to the accumulation of intracellular ionized calcium in patients with PIH. Calcium 291-298 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 221-224 8287719-4 1993 By contrast, calcium metabolism imbalance was seen in patients with moderate and severe PIH. Calcium 13-20 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 88-91 8287719-6 1993 The pattern of calcium metabolism in normal pregnancy was summarized, and the pathogenesis of PIH related to calcium metabolism was discussed. Calcium 109-116 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 94-97 8287719-7 1993 The study provides an important basis for calcium supplementation during pregnancy and for using calcium antagonists to treat PIH patient. Calcium 97-104 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 126-129 1893237-2 1991 This article reviews work indicating that dietary calcium supplementation can sharply reduce the PIH incidence among pregnant women whose regular diet is calcium-poor. Calcium 50-57 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 97-100 1828158-3 1991 Recently a causal relationship has been suggested between dietary calcium deficiency and PIH, with the proposal that calcium supplements be given throughout pregnancy in order to prevent the disease. Calcium 66-73 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 89-92 1828158-4 1991 This article reviews a series of clinical tests carried out over a six-year period which have demonstrated that calcium supplementation is an effective low-cost measure for reducing the frequency of PIH in women whose intake of the mineral is low. Calcium 112-119 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 199-202 1828158-5 1991 It is not yet known how calcium reduces the risk of PIH. Calcium 24-31 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 52-55 1893237-2 1991 This article reviews work indicating that dietary calcium supplementation can sharply reduce the PIH incidence among pregnant women whose regular diet is calcium-poor. Calcium 154-161 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 97-100 1893237-3 1991 It also describes physiologic conditions prevailing during pregnancy that could explain calcium"s major role in PIH--as well as supplemental calcium"s great potential for preventing PIH among people with low-calcium diets. Calcium 88-95 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 112-115 1893237-3 1991 It also describes physiologic conditions prevailing during pregnancy that could explain calcium"s major role in PIH--as well as supplemental calcium"s great potential for preventing PIH among people with low-calcium diets. Calcium 141-148 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 182-185 1893237-3 1991 It also describes physiologic conditions prevailing during pregnancy that could explain calcium"s major role in PIH--as well as supplemental calcium"s great potential for preventing PIH among people with low-calcium diets. Calcium 141-148 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 182-185 2591603-2 1989 However, it might be decreased in women with pregnancy induced hypertension (PIH) by estimating serum calcium levels, serum levels of calcium regulating hormones and calcium secretion into the urine. Calcium 102-109 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 77-80 2692881-2 1989 In comparison with normal pregnant women and normal non-pregnant women, women with PIH showed an increase in heart rate, suggesting an increased peripheral sympathetic tone, and an initial derangement in renal function as shown by the increase in serum uric acid and reduction in sodium excretion and total and fractional calcium excretion at any given level of sodium excretion. Calcium 322-329 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 83-86 2591603-2 1989 However, it might be decreased in women with pregnancy induced hypertension (PIH) by estimating serum calcium levels, serum levels of calcium regulating hormones and calcium secretion into the urine. Calcium 134-141 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 77-80 2591603-2 1989 However, it might be decreased in women with pregnancy induced hypertension (PIH) by estimating serum calcium levels, serum levels of calcium regulating hormones and calcium secretion into the urine. Calcium 134-141 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 77-80 30990249-9 2019 Calcium supplementation and lowering the BMI might have the potential benefit on reducing the prevalence of PIH in selected women. Calcium 0-7 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 108-111 3781066-1 1986 Serum concentrations of total calcium, ionized calcium and inorganic phosphorus in severe PIH were significantly lower than those in normal pregnancy during the 3rd trimester of pregnancy and continued to be low even at puerperium. Calcium 30-37 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 90-93 3781066-1 1986 Serum concentrations of total calcium, ionized calcium and inorganic phosphorus in severe PIH were significantly lower than those in normal pregnancy during the 3rd trimester of pregnancy and continued to be low even at puerperium. Calcium 47-54 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 90-93 30766591-1 2018 Background: Calcium is a major nutrient implicated in pregnancy-induced hypertension (PIH). Calcium 12-19 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 86-89 30766591-2 2018 Aside dietary sources, geophagia has been reported to provide calcium needed to prevent PIH. Calcium 62-69 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 88-91 28035193-2 2016 Calcium supplementation has been shown to reduce the risk of PE/E for pregnant women and preterm birth. Calcium 0-7 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 61-65 30332997-1 2018 BACKGROUND: Evidence suggests that daily supplementation of 1500 to 2000 mg of calcium during pregnancy reduces pregnancy-induced hypertension (PIH). Calcium 79-86 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 144-147 30332997-2 2018 However, the evidence on the efficacy of low-dose calcium supplementation on PIH is limited. Calcium 50-57 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 77-80 30332997-5 2018 The modified Poisson regression model was used to estimate the association (risk ratio) between consumption of calcium tablets and PIH. Calcium 111-118 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 131-134 30332997-7 2018 CONCLUSIONS: Daily supplementation of 500 mg oral calcium during pregnancy for at least 180 tablets is associated with a considerably reduced risk of PIH, but this study is unable to confirm whether this association is causal. Calcium 50-57 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 150-153 28035193-3 2016 This study presents findings from a cost-effectiveness analysis of a pilot project, which provided calcium supplementation through the public sector to pregnant women during antenatal care for PE/E prevention as compared to existing PE/E management in Nepal. Calcium 99-106 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 193-197 28035193-13 2016 CONCLUSIONS: Calcium supplementation for pregnant mothers for prevention of PE/E provided with MgSO4 for treatment holds promise for the cost-effective reduction of maternal and neonatal morbidity and mortality associated with PE/E. Calcium 13-20 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 76-80 28035193-13 2016 CONCLUSIONS: Calcium supplementation for pregnant mothers for prevention of PE/E provided with MgSO4 for treatment holds promise for the cost-effective reduction of maternal and neonatal morbidity and mortality associated with PE/E. Calcium 13-20 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 227-231 25410280-9 2014 Women with hypertensive disorders (PE and PIH) had significantly lower serum calcium and magnesium levels than those in the control group (p < 0.0001 each). Calcium 77-84 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 42-45 26930501-1 2016 OBJECTIVE: The relationship between serum zinc, magnesium, and calcium levels and pregnancy-induced hypertension (PIH) is controversial. Calcium 63-70 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 114-117 26930501-6 2016 The results of the meta-analysis indicated that patients with PIH had lower serum zinc (SMD = -1.14; 95% CI] = -1.69, -0.59; P < 0.05), calcium (MD = -0.26; 95% CI = -0.36, -0.15; P < 0.05), and magnesium concentration (MD = -0.0.06; 95% CI = -0.08, -0.05; P < 0.05) than healthy gravidas. Calcium 139-146 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 62-65 26930501-7 2016 CONCLUSION: Our research suggests that serum zinc, calcium, and magnesium concentrations may have an effect on PIH. Calcium 51-58 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 111-114 25410280-13 2014 CONCLUSION: In this study population, serum calcium and magnesium levels are lower in PIH and PE than in normal pregnancy. Calcium 44-51 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 86-89 21209254-6 2011 The Sweet Pee mutants had improved glucose tolerance, higher urinary excretion of calcium and magnesium, and growth retardation. Calcium 82-89 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 10-13 16580574-1 2006 BACKGROUND: The aim of the present study was to determine whether the beneficial effect of oral supplementation with calcium and conjugated linoleic acid (CLA) in the reduction of the incidence of pregnancy-induced hypertension (PIH) is related with changes in plasma levels of prostanoids, renin, angiotensin II, calciotropic hormones, and plasma and intracellular ionized free calcium. Calcium 117-124 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 229-232 16580574-1 2006 BACKGROUND: The aim of the present study was to determine whether the beneficial effect of oral supplementation with calcium and conjugated linoleic acid (CLA) in the reduction of the incidence of pregnancy-induced hypertension (PIH) is related with changes in plasma levels of prostanoids, renin, angiotensin II, calciotropic hormones, and plasma and intracellular ionized free calcium. Calcium 379-386 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 229-232 16580574-7 2006 The women who developed PIH (n = 12) presented a significant increase in the concentrations of intracellular calcium after interventions (120 nmol/L [range 89.2 to 240 nmol/L] v 137.5 nmol/L [range 89.2 to 138 nmol/L; P = .02). Calcium 109-116 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 24-27 16580574-8 2006 CONCLUSIONS: Calcium and CLA supplementation during pregnancy reduces the incidence of PIH, and decreases the intracellular concentration of ionized free calcium in peripheral blood lymphocytes. Calcium 13-20 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 87-90 16243339-1 2005 OBJECTIVE: To determine the effect of dietary supplementation of calcium plus conjugated linoleic acid (calcium-CLA) in reducing the incidence of vascular endothelial dysfunction in pregnant women at high risk of developing pregnancy-induced hypertension (PIH). Calcium 65-72 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 256-259