PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7723245-1	1995	beta 2-microglobulin (beta 2m) induces an osteoclast-mediated net calcium efflux from neonatal mouse calvariae which occurs only after 48 hours of incubation, suggesting that beta 2m acts via other growth factors.	Calcium	66-73	beta-2 microglobulin	Mus musculus	0-20	
10760095-5	2000	RESULTS: In calvariae, beta2m induced a time- and dose-dependent calcium release, which was maximum following a 48-hour incubation at a concentration of 10-5 mol/L.	Calcium	65-72	beta-2 microglobulin	Mus musculus	23-29	
7723245-1	1995	beta 2-microglobulin (beta 2m) induces an osteoclast-mediated net calcium efflux from neonatal mouse calvariae which occurs only after 48 hours of incubation, suggesting that beta 2m acts via other growth factors.	Calcium	66-73	beta-2 microglobulin	Mus musculus	22-29	
7723245-1	1995	beta 2-microglobulin (beta 2m) induces an osteoclast-mediated net calcium efflux from neonatal mouse calvariae which occurs only after 48 hours of incubation, suggesting that beta 2m acts via other growth factors.	Calcium	66-73	beta-2 microglobulin	Mus musculus	175-182	
7723245-4	1995	However, the difference (delta) between the calcium efflux induced in calvariae incubated with and without beta 2m in basal medium and that in calvariae incubated with and without beta 2m in indomethacin supplemented medium was similar, suggesting a prostaglandin independent mechanism.	Calcium	44-51	beta-2 microglobulin	Mus musculus	107-114	
7723245-6	1995	In contrast, pre-incubating calvariae with either anti-IL-1 beta or IL-1 beta RA did not alter basal calcium efflux but completely blocked the beta 2m induced calcium efflux.	Calcium	159-166	beta-2 microglobulin	Mus musculus	143-150	
7723245-8	1995	Thus, the beta 2m-induced calcium efflux observed in neonatal mouse calvariae is dependent on interleukin-1 beta but not prostaglandins.	Calcium	26-33	beta-2 microglobulin	Mus musculus	10-17	
1415583-0	1992	Beta 2-microglobulin induces calcium efflux from cultured neonatal mouse calvariae.	Calcium	29-36	beta-2 microglobulin	Mus musculus	0-20	
1415583-4	1992	Following a 48-h but not 3- or 24-h incubation, beta 2M (10(-8)-10(-6) M) induced a net calcium efflux.	Calcium	88-95	beta-2 microglobulin	Mus musculus	48-55	
1415583-8	1992	Calcitonin, an osteoclast inhibitor, blocked the beta 2M-induced calcium efflux and beta-glucuronidase release, suggesting osteoclast involvement.	Calcium	65-72	beta-2 microglobulin	Mus musculus	49-56	
1415583-9	1992	Thus beta 2M induces a dose- and time-dependent, cell-mediated calcium efflux from neonatal mouse calvariae that involves osteoclast stimulation.	Calcium	63-70	beta-2 microglobulin	Mus musculus	5-12