PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25815641-2	2015	Recently, calcium (Ca(2+))/calmodulin(CaM)-dependent protein kinase II (CaMKII) has emerged as a critical regulator of Na(V)1.5 function through phosphorylation of multiple residues including S516, T594, and S571, and these phosphorylation events may be important for the genesis of acquired arrhythmias, which occur in heart failure.	Calcium	10-17	immunoglobulin lambda variable 2-18	Homo sapiens	119-127	
21167176-1	2011	The function of the human voltage-gated sodium channel Na(V)1.5 is regulated in part by intracellular calcium signals.	Calcium	102-109	immunoglobulin lambda variable 2-18	Homo sapiens	55-63	
21167176-2	2011	The ubiquitous calcium sensor protein calmodulin (CaM) is an important part of the complex calcium-sensing apparatus in Na(V)1.5.	Calcium	15-22	immunoglobulin lambda variable 2-18	Homo sapiens	120-128	
21167176-7	2011	Sequence similarities between voltage-gated sodium channels and voltage-gated calcium channels suggest that the structure of the CaM-Na(V)1.5 IQ motif complex can serve as a general model for the interaction between CaM and ion channel IQ motifs under low-calcium conditions.	Calcium	78-85	immunoglobulin lambda variable 2-18	Homo sapiens	133-141