PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1541903-6	1992	In analyzing the signal induced by anti-class II MHC mAb"s we have demonstrated that cross-linking of the class II MHC antigens with intact mAb"s, or with F(ab")2 fragments of anti-class II MHC mAb"s and F(ab")2 fragments of rabbit antimouse (RAM) immunoglobulin G, produced an intracellular calcium rise.	Calcium	292-299	major histocompatibility complex, class I, C	Homo sapiens	49-52	
1541903-6	1992	In analyzing the signal induced by anti-class II MHC mAb"s we have demonstrated that cross-linking of the class II MHC antigens with intact mAb"s, or with F(ab")2 fragments of anti-class II MHC mAb"s and F(ab")2 fragments of rabbit antimouse (RAM) immunoglobulin G, produced an intracellular calcium rise.	Calcium	292-299	major histocompatibility complex, class I, C	Homo sapiens	115-118	
1541903-6	1992	In analyzing the signal induced by anti-class II MHC mAb"s we have demonstrated that cross-linking of the class II MHC antigens with intact mAb"s, or with F(ab")2 fragments of anti-class II MHC mAb"s and F(ab")2 fragments of rabbit antimouse (RAM) immunoglobulin G, produced an intracellular calcium rise.	Calcium	292-299	major histocompatibility complex, class I, C	Homo sapiens	115-118	
2469725-1	1989	Cross-linking class I MHC molecules on human T cell clones by reacting them with various mAb directed at either monomorphic or polymorphic determinants on class I MHC molecules followed by cross-linking with GaMIg stimulated a rise in intracellular free calcium concentration ([Ca2+]i), and induced proliferation and IL-2 production.	Calcium	254-261	major histocompatibility complex, class I, C	Homo sapiens	22-25	
2469725-1	1989	Cross-linking class I MHC molecules on human T cell clones by reacting them with various mAb directed at either monomorphic or polymorphic determinants on class I MHC molecules followed by cross-linking with GaMIg stimulated a rise in intracellular free calcium concentration ([Ca2+]i), and induced proliferation and IL-2 production.	Calcium	254-261	major histocompatibility complex, class I, C	Homo sapiens	163-166	
2450913-10	1988	Finally it was demonstrated that adding GaMIg to T4 cells reacted with mAb to class I MHC Ag but not CD11a resulted in an increase in intracellular calcium concentration.	Calcium	148-155	major histocompatibility complex, class I, C	Homo sapiens	86-89	
2450913-11	1988	The data demonstrate that cross-linking class I MHC molecules results in the generation of at least one activation signal, a rise in intracellular calcium concentration, and, thereby, stimulates human T4 cells.	Calcium	147-154	major histocompatibility complex, class I, C	Homo sapiens	48-51	
16766611-3	2006	Specificity characteristics improve as the time window for detection increases, saturating for time periods on the timescale of downregulation; thus, the calcium spike (30 s) has low specificity but a sensitivity to single-peptide MHC ligands, while the cytokine threshold (1 h) can distinguish ligands with a 30% variation in the complex lifetime.	Calcium	154-161	major histocompatibility complex, class I, C	Homo sapiens	231-234	
16860761-3	2006	Calcium signaling via TCR was blocked within 2 min by anti-MHCp treatment and 1 min by latrunculin-A treatment.	Calcium	0-7	major histocompatibility complex, class I, C	Homo sapiens	59-63	
12690105-1	2003	Recognition by CD8+ cytotoxic T lymphocytes (CTLs) of antigenic peptides bound to major histocompatibility class (MHC) I molecules on target cells leads to sustained calcium mobilization and CTL degranulation resulting in perforin-dependent killing.	Calcium	166-173	major histocompatibility complex, class I, C	Homo sapiens	114-117	
9742454-2	1998	To date, the amino-acid sequence of the MHC of calcium-regulated myosins is known only for two closely related species of scallops.	Calcium	47-54	major histocompatibility complex, class I, C	Homo sapiens	40-43	
9742454-7	1998	The deduced amino-acid sequence shows the squid MHC to be 72-73% identical and 86-87% similar to the calcium-regulated scallop MHCs cloned previously.	Calcium	101-108	major histocompatibility complex, class I, C	Homo sapiens	48-51	
21563272-8	2011	MHC and ICAM-1 molecules anchored on the bilayer diffused freely and stimulated T cell calcium flux and adhesion, respectively.	Calcium	87-94	major histocompatibility complex, class I, C	Homo sapiens	0-3