PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16005069-10 2005 In BV-2 cells and primary astrocytes, the expression of TNFalpha and IL-1beta analyzed by real-time polymerase chain reaction was downregulated at 6 or 24 h. In all cell types tested the FB1 treatment caused accumulation of free sphinganine and decrease in free sphingosine levels at selected time points. safingol 229-240 interleukin 1 beta Mus musculus 69-77