PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14597763-7 2003 In Arnt-null epidermis, 4-sphingenine was largely replaced by sphinganine and the amounts of ceramides with 4-hydroxysphinganine were greatly decreased, suggesting deficiency of dihydroceramide desaturases that catalyze the formation of both 4-sphingenyl and 4-hydroxysphinganyl moieties. safingol 62-73 aryl hydrocarbon receptor nuclear translocator Mus musculus 3-7