PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12868960-6 2003 Interestingly, IFN-gamma led to an induction of the CNT1- and CNT2-related nucleoside transport activities independent of STAT1, thus ensuring the supply of extracellular nucleosides for the STAT1-independent RNA synthesis. Nucleosides 75-85 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 Mus musculus 52-56 20060452-2 2010 Here, using a clone of mouse CNT1 (mCNT1), we investigated its transport characteristics and substrate specificity for synthetic nucleoside analogues, and compared them with those of human CNT1 (hCNT1). Nucleosides 129-139 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 Mus musculus 29-33 20060452-2 2010 Here, using a clone of mouse CNT1 (mCNT1), we investigated its transport characteristics and substrate specificity for synthetic nucleoside analogues, and compared them with those of human CNT1 (hCNT1). Nucleosides 129-139 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 Mus musculus 35-40 20060452-3 2010 In mCNT1-transfected Cos-7 cells, pyrimidine, but not purine, nucleosides showed sodium- and concentration-dependent uptake, and uridine uptake was competitively inhibited by uridine analogues, the rank order of the inhibitory effects being 5-bromouridine>3"-deoxyuridine>2"-deoxyuridine. Nucleosides 62-73 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 Mus musculus 3-8 20060452-4 2010 cis- and trans-Inhibition studies involving synthetic nucleoside drugs revealed that gemcitabine and zidovudine greatly inhibited [(3)H]uridine uptake mediated by mCNT1 in the both cases, while cytarabine and zalcitabine showed small cis-inhibitory effect, and no trans-inhibitory effect on the uptake. Nucleosides 54-64 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 Mus musculus 163-168 12868960-6 2003 Interestingly, IFN-gamma led to an induction of the CNT1- and CNT2-related nucleoside transport activities independent of STAT1, thus ensuring the supply of extracellular nucleosides for the STAT1-independent RNA synthesis. Nucleosides 171-182 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 Mus musculus 52-56