PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29323872-1 2018 Fludarabine, a nucleoside analogue antimetabolite, has complicated pharmacokinetics requiring facilitated transmembrane transport and intracellular conversion to triphosphate nucleotide form (Ara-FATP), causing it to be susceptible to emergence of drug resistance. Nucleosides 15-25 solute carrier family 27 member 1 Homo sapiens 196-200 29323872-4 2018 We show that Ara-FATP has limited cytotoxic activity toward investigated cells relative to free nucleoside (Ara-FA), but complexation with the glycodendrimer (which does not otherwise influence cellular metabolism) drastically increases its toxicity. Nucleosides 96-106 solute carrier family 27 member 1 Homo sapiens 17-21