PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35565857-0 2022 Piceatannol SNEDDS Attenuates Estradiol-Induced Endometrial Hyperplasia in Rats by Modulation of NF-kappaB and Nrf2/HO-1 Axes. 3,3',4,5'-tetrahydroxystilbene 0-11 heme oxygenase 1 Rattus norvegicus 116-120 33519479-0 2020 Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NFkappaB Axis. 3,3',4,5'-tetrahydroxystilbene 0-11 heme oxygenase 1 Rattus norvegicus 103-107 31197431-0 2019 Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-kappaB inflammatory cascade. 3,3',4,5'-tetrahydroxystilbene 0-11 heme oxygenase 1 Rattus norvegicus 77-81 31197431-11 2019 Therefore, PIC may protect against cisplatin-induced nephrotoxicity by modulating Nrf2/HO-1 signaling and hindering the inflammatory and apoptotic pathways. 3,3',4,5'-tetrahydroxystilbene 11-14 heme oxygenase 1 Rattus norvegicus 87-91 22022464-3 2011 The aim of this study is to elucidate whether Akt/HO-1 plays any role in astringinin-mediated attenuation of hepatic injury following trauma-hemorrhage. 3,3',4,5'-tetrahydroxystilbene 73-84 heme oxygenase 1 Rattus norvegicus 50-54 31323227-0 2019 Piceatannol alleviates inflammation and oxidative stress via modulation of the Nrf2/HO-1 and NF-kappaB pathways in diabetic cardiomyopathy. 3,3',4,5'-tetrahydroxystilbene 0-11 heme oxygenase 1 Rattus norvegicus 84-88 31323227-10 2019 Importantly, knockdown of Nrf2 suppressed PIC-mediated activation of the Nrf2/HO-1 pathway and abolished its anti-inflammatory effects. 3,3',4,5'-tetrahydroxystilbene 42-45 heme oxygenase 1 Rattus norvegicus 78-82 22022464-9 2011 Astringinin treatment also increased hepatic Akt activation and HO-1 expression as compared with vehicle-treated trauma-hemorrhaged rats. 3,3',4,5'-tetrahydroxystilbene 0-11 heme oxygenase 1 Rattus norvegicus 64-68 22022464-11 2011 These findings collectively suggest that the salutary effects of astringinin administration on attenuation of hepatic injury after trauma-hemorrhage are likely mediated via Akt dependent HO-1 up-regulation. 3,3',4,5'-tetrahydroxystilbene 65-76 heme oxygenase 1 Rattus norvegicus 187-191