PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19887493-5	2010	Western blot analysis showed that PDGF-BB-induced phosphorylation of Akt, p70S6K, and p38 was inhibited by piceatannol, but not resveratrol.	3,3',4,5'-tetrahydroxystilbene	107-118	mitogen-activated protein kinase 14	Homo sapiens	86-89	
22705645-6	2012	Piceatannol treatment induced p38 MAPK phosphorylation but inactivation of Akt and ERK.	3,3',4,5'-tetrahydroxystilbene	0-11	mitogen-activated protein kinase 14	Homo sapiens	30-33	
20580678-0	2010	Piceatannol induces Fas and FasL up-regulation in human leukemia U937 cells via Ca2+/p38alpha MAPK-mediated activation of c-Jun and ATF-2 pathways.	3,3',4,5'-tetrahydroxystilbene	0-11	mitogen-activated protein kinase 14	Homo sapiens	85-93	
20580678-2	2010	Piceatannol-induced apoptotic death of human leukemia U937 cells was characterized by increase in intracellular Ca(2+) concentration ([Ca(2+)]i), ERK inactivation, p38 MPAK activation, degradation of procaspase-8 and production of t-Bid.	3,3',4,5'-tetrahydroxystilbene	0-11	mitogen-activated protein kinase 14	Homo sapiens	164-167	
20580678-5	2010	Abolition of piceatannol-induced increase in [Ca(2+)]i abrogated p38 MAPK activation and up-regulation of Fas and FasL expression, but restored ERK activation and viability of piceatannol-treated cells.	3,3',4,5'-tetrahydroxystilbene	13-24	mitogen-activated protein kinase 14	Homo sapiens	65-68	
20580678-6	2010	Suppression of p38alpha MAPK or transfection of constitutively active MEK1 abolished piceatannol-induced Fas and FasL up-regulation.	3,3',4,5'-tetrahydroxystilbene	85-96	mitogen-activated protein kinase 14	Homo sapiens	15-23	
20580678-7	2010	Piceatannol treatment repressed ERK-mediated c-Fos phosphorylation but evoked p38alpha MAPK-mediated c-Jun and ATF-2 phosphorylation.	3,3',4,5'-tetrahydroxystilbene	0-11	mitogen-activated protein kinase 14	Homo sapiens	78-86	
20580678-9	2010	Taken together, our data indicate that Fas/FasL up-regulation in piceatannol-treated U937 cells is elicited by Ca(2+)/p38alpha MAPK-mediated activation of c-Jun and ATF-2, and suggest that autocrine Fas-mediated apoptotic mechanism is involved in piceatannol-induced cell death.	3,3',4,5'-tetrahydroxystilbene	65-76	mitogen-activated protein kinase 14	Homo sapiens	118-126	
20580678-9	2010	Taken together, our data indicate that Fas/FasL up-regulation in piceatannol-treated U937 cells is elicited by Ca(2+)/p38alpha MAPK-mediated activation of c-Jun and ATF-2, and suggest that autocrine Fas-mediated apoptotic mechanism is involved in piceatannol-induced cell death.	3,3',4,5'-tetrahydroxystilbene	247-258	mitogen-activated protein kinase 14	Homo sapiens	118-126	
14691575-8	2004	How-ever, phosphorylation of p38MAPK was prevented by the tyro-sine kinase Syk inhibitor piceatannol.	3,3',4,5'-tetrahydroxystilbene	89-100	mitogen-activated protein kinase 14	Homo sapiens	29-36	
12038794-6	2002	Both 8-iso-PGF2alpha and U46619-induced p38 MAP kinase phosphorylation in suspended platelets and this was inhibited by piceatannol, indicating that Syk activation occurs upstream of p38 MAP kinase phosphorylation.	3,3',4,5'-tetrahydroxystilbene	120-131	mitogen-activated protein kinase 14	Homo sapiens	40-43	
30066852-9	2018	Combined treatment with resveratrol and piceatannol also decreased tumor cell survival as indicated by the upregulation of the DNA damaging marker, gammaH2AX, the cleavage of caspase 3, the downregulation of the survival markers, p38-MAPK/c-Myc, and G1-to-S cell cycle arrest.	3,3',4,5'-tetrahydroxystilbene	40-51	mitogen-activated protein kinase 14	Homo sapiens	230-233