PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15050291-6 2004 Lowered tyrosine phosphorylation of IkappaBalpha may be due to a decrease in activity of p56(lck) and ZAP-70, since treatment with piceatannol, an inhibitor of syk and src family kinases, mimics age associated decline in tyrosine phosphorylation of IkappaBalpha in T cells from young donors. 3,3',4,5'-tetrahydroxystilbene 131-142 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 168-171 12435267-6 2003 The following observations imply that Syk is such a kinase: (i) beta(2) integrins activated Syk in a Src-dependent manner, (ii) Syk was associated with Cbl much longer than Fgr was, and (iii) the Syk inhibitor piceatannol (3,4,3",5"-tetrahydroxy- trans -stilbene) abolished the Cbl-associated kinase activity in an in vitro assay. 3,3',4,5'-tetrahydroxystilbene 210-221 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 101-104 12435267-6 2003 The following observations imply that Syk is such a kinase: (i) beta(2) integrins activated Syk in a Src-dependent manner, (ii) Syk was associated with Cbl much longer than Fgr was, and (iii) the Syk inhibitor piceatannol (3,4,3",5"-tetrahydroxy- trans -stilbene) abolished the Cbl-associated kinase activity in an in vitro assay. 3,3',4,5'-tetrahydroxystilbene 223-262 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 101-104 14982949-3 2004 We found that Src inhibitor PP2 and Syk inhibitor piceatannol inhibited phagocytosis, macrophage-inflammatory protein-1alpha (MIP-1alpha) release, as well as phosphorylation of extracellular-regulated kinase (ERK) and Akt, consistent with Src/Syk involvement early in FcgammaR signaling. 3,3',4,5'-tetrahydroxystilbene 50-61 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 239-242 21681336-8 2011 Compared with the control group, after treatment of HeLa cells with STAT3 inhibitor Piceatannol for 24, 48, 72, and 96 h, the cell viability decreased by 23.8%, 29.7%, 37.3% and 45.4% (all P < 0.05), respectively, while increase of c-SRC content could not reverse the inhibitory effect. 3,3',4,5'-tetrahydroxystilbene 84-95 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 235-240