PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12444159-12 2002 Overall, our results clearly demonstrate that hydroxyl groups of stilbenes are critical and that piceatannol, a tetrahydroxystilbene, suppresses NF-kappaB activation induced by various inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation. 3,3',4,5'-tetrahydroxystilbene 97-108 NFKB inhibitor alpha Homo sapiens 227-239 22480333-8 2012 In addition, piceatannol diminished NF-kappaB nuclear translocation through blocking the inhibitor of NF-kappaB alpha (IkappaBalpha) phosphorylation in the cytoplasm. 3,3',4,5'-tetrahydroxystilbene 13-24 NFKB inhibitor alpha Homo sapiens 119-131 15050291-6 2004 Lowered tyrosine phosphorylation of IkappaBalpha may be due to a decrease in activity of p56(lck) and ZAP-70, since treatment with piceatannol, an inhibitor of syk and src family kinases, mimics age associated decline in tyrosine phosphorylation of IkappaBalpha in T cells from young donors. 3,3',4,5'-tetrahydroxystilbene 131-142 NFKB inhibitor alpha Homo sapiens 36-48 15050291-6 2004 Lowered tyrosine phosphorylation of IkappaBalpha may be due to a decrease in activity of p56(lck) and ZAP-70, since treatment with piceatannol, an inhibitor of syk and src family kinases, mimics age associated decline in tyrosine phosphorylation of IkappaBalpha in T cells from young donors. 3,3',4,5'-tetrahydroxystilbene 131-142 NFKB inhibitor alpha Homo sapiens 249-261 12444159-0 2002 Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation. 3,3',4,5'-tetrahydroxystilbene 0-11 NFKB inhibitor alpha Homo sapiens 116-128 12444159-10 2002 When examined for the mechanism, we found that piceatannol inhibited TNF-induced IkappaBalpha phosphorylation, p65 phosphorylation, p65 nuclear translocation, and IkappaBalpha kinase activation, but had no significant effect on IkappaBalpha degradation. 3,3',4,5'-tetrahydroxystilbene 47-58 NFKB inhibitor alpha Homo sapiens 81-93 12444159-10 2002 When examined for the mechanism, we found that piceatannol inhibited TNF-induced IkappaBalpha phosphorylation, p65 phosphorylation, p65 nuclear translocation, and IkappaBalpha kinase activation, but had no significant effect on IkappaBalpha degradation. 3,3',4,5'-tetrahydroxystilbene 47-58 NFKB inhibitor alpha Homo sapiens 163-175 12444159-10 2002 When examined for the mechanism, we found that piceatannol inhibited TNF-induced IkappaBalpha phosphorylation, p65 phosphorylation, p65 nuclear translocation, and IkappaBalpha kinase activation, but had no significant effect on IkappaBalpha degradation. 3,3',4,5'-tetrahydroxystilbene 47-58 NFKB inhibitor alpha Homo sapiens 163-175