PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33266353-2 2020 Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer via down Regulation of Nuclear p65 and HIF-1alpha. 3,3',4,5'-tetrahydroxystilbene 30-41 RELA proto-oncogene, NF-kB subunit Homo sapiens 123-126 35173833-9 2022 Finally, we confirmed that reducing of nuclear factor kappa B (NF-kappaB)/p65 activation and elimination of reactive oxygen species (ROS) were involved in the protective effect of PIC against glucolipotoxicity-induced vascular barrier injury. 3,3',4,5'-tetrahydroxystilbene 180-183 RELA proto-oncogene, NF-kB subunit Homo sapiens 74-77 31906321-0 2020 Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer Via Downregulation of Nuclear p65 and HIF-1alpha. 3,3',4,5'-tetrahydroxystilbene 30-41 RELA proto-oncogene, NF-kB subunit Homo sapiens 122-125 31906321-5 2020 Our results indicate that PIC-BSA NPs were more effective in downregulating the expression of nuclear p65 and HIF-1alpha in colon cancer cells as compared to free PIC. 3,3',4,5'-tetrahydroxystilbene 26-29 RELA proto-oncogene, NF-kB subunit Homo sapiens 102-105 12444159-12 2002 Overall, our results clearly demonstrate that hydroxyl groups of stilbenes are critical and that piceatannol, a tetrahydroxystilbene, suppresses NF-kappaB activation induced by various inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation. 3,3',4,5'-tetrahydroxystilbene 97-108 RELA proto-oncogene, NF-kB subunit Homo sapiens 251-254 20155627-6 2009 Piceatannol also inhibited TPA-induced phosphorylation and degradation of Ikappa Balpha as well as nuclear translocation of the phosphorylated form of p65, the functionally active subunit of NF-kappa B. 3,3',4,5'-tetrahydroxystilbene 0-11 RELA proto-oncogene, NF-kB subunit Homo sapiens 151-154 12444159-0 2002 Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation. 3,3',4,5'-tetrahydroxystilbene 0-11 RELA proto-oncogene, NF-kB subunit Homo sapiens 140-143 12444159-10 2002 When examined for the mechanism, we found that piceatannol inhibited TNF-induced IkappaBalpha phosphorylation, p65 phosphorylation, p65 nuclear translocation, and IkappaBalpha kinase activation, but had no significant effect on IkappaBalpha degradation. 3,3',4,5'-tetrahydroxystilbene 47-58 RELA proto-oncogene, NF-kB subunit Homo sapiens 111-114 12444159-10 2002 When examined for the mechanism, we found that piceatannol inhibited TNF-induced IkappaBalpha phosphorylation, p65 phosphorylation, p65 nuclear translocation, and IkappaBalpha kinase activation, but had no significant effect on IkappaBalpha degradation. 3,3',4,5'-tetrahydroxystilbene 47-58 RELA proto-oncogene, NF-kB subunit Homo sapiens 132-135