PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19631264-3	2009	The treatment of cells with piceatannol inhibited cell proliferation by reducing extracellular signal-regulated kinase (ERK) 1/2 and JNK activity in cultured VSMC in the presence of tumor necrosis factor-alpha (TNF-alpha).	3,3',4,5'-tetrahydroxystilbene	28-39	mitogen-activated protein kinase 8	Homo sapiens	133-136	
17095576-7	2007	Piceatannol, an inhibitor of Syk tyrosine kinase, or infection of Syk small interference RNA blocked the recombinant CRP-induced RhoA activity and the phosphorylation of JNK and IRS-1.	3,3',4,5'-tetrahydroxystilbene	0-11	mitogen-activated protein kinase 8	Homo sapiens	170-173	
14699155-6	2004	Inhibition of Syk with piceatannol or PI3K with wortmannin inhibited LPS-induced JNK activation and decreased MCP-1 expression after exposure to LPS, suggesting that both Syk and PI3K reside in a signaling pathway leading to LPS-induced JNK activation in neutrophils.	3,3',4,5'-tetrahydroxystilbene	23-34	mitogen-activated protein kinase 8	Homo sapiens	81-84	
11053415-7	2001	JNK activation was attenuated by blocking antibodies to beta2 integrins, the tyrosine kinase inhibitors, genistein, and tyrphostin A9, a Pyk2-specific inhibitor, and piceatannol, a Syk-specific inhibitor.	3,3',4,5'-tetrahydroxystilbene	166-177	mitogen-activated protein kinase 8	Homo sapiens	0-3	
11154209-4	2001	SAPK1/JNK1 activation was blocked by piceatannol, indicating that it is regulated by Syk kinase, whereas SAPK2/p38 activation was inhibited by PP2, revealing an upstream regulation by Src-like kinases.	3,3',4,5'-tetrahydroxystilbene	37-48	mitogen-activated protein kinase 8	Homo sapiens	0-5	
11154209-4	2001	SAPK1/JNK1 activation was blocked by piceatannol, indicating that it is regulated by Syk kinase, whereas SAPK2/p38 activation was inhibited by PP2, revealing an upstream regulation by Src-like kinases.	3,3',4,5'-tetrahydroxystilbene	37-48	mitogen-activated protein kinase 8	Homo sapiens	6-10	
10528214-3	1999	While ERK activation is rapid and transient, peaking at 10 min, the JNK1 activation is delayed and more sustained reaching a maximum at 2 h. ERK activation was blocked by CP 118556, indicating it is regulated by a Src-like kinase, while JNK1 was inhibited by piceatannol, revealing an upstream regulation by Syk.	3,3',4,5'-tetrahydroxystilbene	259-270	mitogen-activated protein kinase 8	Homo sapiens	68-72	
32914125-6	2020	Moreover, piceatannol significantly suppressed FA-induced oxidative stress and inhibited phosphorylation of c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinases 1/2 (ERK1/2).	3,3',4,5'-tetrahydroxystilbene	10-21	mitogen-activated protein kinase 8	Homo sapiens	108-131	
32914125-6	2020	Moreover, piceatannol significantly suppressed FA-induced oxidative stress and inhibited phosphorylation of c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinases 1/2 (ERK1/2).	3,3',4,5'-tetrahydroxystilbene	10-21	mitogen-activated protein kinase 8	Homo sapiens	133-136